báo cáo hóa học:" Trastuzumab Sensitizes Ovarian Cancer Cells to EGFR-targeted Therapeutics" docx

... receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2. Cancer ... cancer: taking the HER2 protooncogene to the clinic. J Clin Immunol 1991, 11:117-127. doi: 10.1186/1757-2215-3-7 Cite this article as: Wilken et al., Trastuzumab Sensitizes Ovarian...

Ngày tải lên: 20/06/2014, 07:20

... the major factors contributing to the origin of ovarian cancer stem cells. Emerging evidence suggests that ovarian cancer stem cells are relatively resistant to conventional cytotoxic chemotherapeutic ... any cytotoxicity [19]. Genistein can also induce both apoptosis and autophagic cell death in ovarian cancer cells [20]; however the role of genistein in chemo-resistant...

Ngày tải lên: 20/06/2014, 07:20

... of Mucins in Ovarian Cancer The acquirement of an invasive phenotype is one of the pivotal features of malignant ovarian cells. In order to progress and metastasize, ovarian cancer cells must lose cell ... cancer cells [65,66]. Moreover, MUC16/CA125 expression has been shown to inhibit the cytotoxic responses of human natural killer (NK) cells and downregulate CD16 acti...

Ngày tải lên: 20/06/2014, 07:20

... medical and pathological reports to confirm the presence of ovarian cancer and/or endometriosis. Histological types of ovarian cancer were obtained for ovarian cancer asso- ciated or not associated ... with endometriosis were present, as well as 292 with ovarian cancer. A total of 41 women had ovarian cancer and endometriosis. Codes for ovarian cancer and endometriosi...

Ngày tải lên: 20/06/2014, 07:20

... Circulating endothelial cells, bone marrow- derived endothelial progenitor cells and proangiogenic hematopoietic cells in cancer: From biology to therapy. Crit Rev Oncol Hematol 2009, 69(2):108-24. 19. ... with adenoviral vectors encoding the artificial receptor (AR). The artificial receptor to target MSC to ovarian carci- noma was first constructed using the pDisplay mamma- li...

Ngày tải lên: 20/06/2014, 07:20

... microenvironment where only cancer cells can proliferate and survive. Inhibiting these pathways by blocking proton pumps and transporters may deprive cancer cells of a key mechanism of detoxification and ... cancer cells [5,6]. We propose that the development of new anti -cancer therapies should include a focus on understanding both abnormal glucose metabolism and mechanisms us...

Ngày tải lên: 18/06/2014, 16:20

... between cancer cells and their microenvironment. In the Wa shing pattern, successive waves of cancer cells may induce progressive conditioning of the microenvir- onment to facilitate cancer ce ... Li * Abstract Background: Cancer invasion results from constant interactions between cancer cells and their microenvironment. Major components of the cancer microenvironment are...

Ngày tải lên: 18/06/2014, 16:20

... stem cells are more resistant to the chemotherapeutic agents temozo- lomide, carboplatin, paclitaxel and etoposide compared to CD133 - cells [28]. Neuroblastoma and mou se ovarian cancer SP cells ... trans- formation of normal stem cells to cancerous stem cells or from the dedifferentiation and transformation of progeni- tor or terminally-differentiated cells to tumor...

Ngày tải lên: 20/06/2014, 04:20

... stem cells are more resistant to the chemotherapeutic agents temozo- lomide, carboplatin, paclitaxel and etoposide compared to CD133 - cells [28]. Neuroblastoma and mou se ovarian cancer SP cells ... trans- formation of normal stem cells to cancerous stem cells or from the dedifferentiation and transformation of progeni- tor or terminally-differentiated cells to tumor...

Ngày tải lên: 20/06/2014, 07:20

... the cancerous and normal tissues of ovaries to obtain information about ovarian cancer at molecular level with FTIR technique. Methods Tissue sampling Tissue samples of 12 cases of ovarian cancer ... normal and cancerous ovarian tissue from different patients were recorded. The infrared spectrum of ovarian cancer tissue was found to be dif- ferent from infrared spectrum of n...

Ngày tải lên: 20/06/2014, 07:20