... of genes that appear to be related to the anti-viral effects. These include OAS2, MX1, MX2, RIG1, genes associated with ubiquitination, and many other genes previously shown to be associated with ... differences in gene expression related to response. Considering that these trials were done a few years apart, and with different populations, there was excellent agreement in the c...
Ngày tải lên: 18/06/2014, 15:20
... gulated genes and 20 down regulated genes listed in Table S1, Additional file 1 (genes with similar or exaggerated expression in IRAK4- deficient cells compared to controls). Some of these genes ... Table 1 Gene expression by qPCR in resting or LPS-activated IRAK4-deficient monocytes relative to gene expression in unstimulated control cells Gene Name Monocytes Resting ... expres...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Copy number and gene expression differences between African American and Caucasian American prostate cancer" docx
... gains or losses are associated with gene expression changes In each noteworthy region, gene expression was com- pared between AA patients having copy number gain ver- sus those with normal copy ... to 14q32.33, was one of the top 20 genes with higher expression in AA compared to CA tumors in the Figure 5 Functional annotation analysis of genes contained within the 4 chromoso...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: "Regulatory T cell frequency in patients with melanoma with different disease stage and course, and modulating effects of high-dose interferon-a 2b treatment" pptx
... effector-memory T cells, we used CD25 expression on CD8 + cellsasaninternalcontrol.Only CD4 + cells expressing CD25 with higher intensities than the CD8 + cells were included in the gate for CD25 high cell ... for CD25 low cell s was set to include cells expressing CD25 at levels above those of the isotype control and unstained cells, but at lower expression levels than the CD25 hig...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học:" Rapid serological detection of autoantibodies associated with Sjögren''''s syndrome" docx
... a common autoimmune dis- order associated with epithelial inflammation and exo- crine gland dysfunction [5]. SjS is often associated with polyclonal B cell activation resulting in the presence ... develop- ment of such assays is that, unlike antibodies associated with infectious agents, the detection of autoantibodies associated with autoimmunity requires more sensitive test...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học: " Prospective evaluation of chronic pain associated with posterior autologous iliac crest bone graft harvest and its effect on postoperative outcome" potx
... complications are associated with worse patient- reported disability and somewhat worse physical health, but not with mental health. These findings suggest that morbidity associated with autologous ... associated with numerous disadvantages, primarily related to addi- tional morbidity incurred at the harvest site. Several stud- ies have identified a surprisingly high rate of com...
Ngày tải lên: 18/06/2014, 18:20
Báo cáo hóa học: " Open Access Cell and gene therapies: moving from research to clinic" pptx
... Access Cell and gene therapies: moving from research to clinic David F Stroncek 1* , Raj K Puri 2 Editorial Cell and gene therapy clinical trials began more than 40 years ago. At some institutions cellular ... some have been associated with unacceptable adverse out comes. However, both cell and gene therapies have now become important potential therapies for incurable diseases...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học:" Primary cultured fibroblasts derived from patients with chronic wounds: a methodology to produce human cell lines and test putative growth factor therapy such as GMCSF" ppt
... then subcultured by a rinse with Puck's saline with EDTA fol- lowed by incubation with Puck's/EDTA/Trypsin. An equal volume of growth medium with serum was added, cells were spun down, resuspended ... stimulated with TGF-β [22] and reduced proliferative response with PDFG-BB [23] as compared with controls. Fibroblasts have been isolated from venous stasis ulcers for in...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" ApoG2 induces cell cycle arrest of nasopharyngeal carcinoma cells by suppressing the c-Myc signaling pathway" pot
... purposes) Arrest of NPC cells at S phase of the cell cycle by treatment with ApoG2Figure 2 Arrest of NPC cells at S phase of the cell cycle by treatment with ApoG2. Arrest of NPC cells at S phase by ... in gossypol-induced cell cycle arrest [9,14], we hypothesized that ApoG2 can also modify some cell cycle regulators, resulting in cell cycle arrest in NPC cells. Consistent with...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo y học: "Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofolate reductase gene in selected Egyptian subjects"
... Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease. Am J Hum Genet. ... Goyette P, Rosenblatt DS, Genest J Jr, Rozen R Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronar...
Ngày tải lên: 03/11/2012, 09:49