báo cáo hóa học:" Activation of PKA, p38 MAPK and ERK1/2 by gonadotropins in cumulus cells is critical for induction of EGF-like factor and TACE/ ADAM17 gene expression during in vitro maturation of porcine COCs" doc

... p38 MAPK and ERK1/2 by gonadotropins in cumulus cells is critical for induction of EGF-like factor and TACE/ ADAM17 gene expression during in vitro maturation of porcine COCs Yasuhisa Yamashita 1 , ... that the expression of EGF-like factor and TACE /ADAM17 in cumulus cells was induced by a PKA-, p38 MAPK- and ERK...

Ngày tải lên: 20/06/2014, 07:20

... the expression of the vaccinia virus I7L gene is under the control of the tetracycline operator/repressor system. In the absence of I7L expression, processing of the major VV core proteins is inhibited ... for the processing of p4a, with processing in each of the wild type virus lanes, repressed processing with the mutant in the absence of TET and increased pr...

Ngày tải lên: 20/06/2014, 04:20

... unpublished observations). This pharmacodynamic effect on B cells is particularly interesting in light of increasing evidence that B cells can regulate tumor cellular immunity. Recent find- ings in murine models ... the inclusion of TLR9 stimulation is important for optimal activation of naïve B cells, a finding of particular impor- tance for patients with advanced...

Ngày tải lên: 18/06/2014, 15:20

... receptors in the induction of PGE 2 production by activated microglial cells. COX-2 is the inducible isoform of the enzyme responsible for the first committed step in PGE 2 synthesis, one of the major ... levels of induction, have been associated with both protective and harmful effects on neurons and glial cells [27]. In micro- glial cells, COX-2 is the ma...

Ngày tải lên: 19/06/2014, 22:20

... NADPH oxidase in the presence of glial iNOS is synergistic in killing co-cultured neuronsFigure 2 Activation of NADPH oxidase in the presence of glial iNOS is synergistic in killing co-cultured ... by microglia, is seen in post-mortem brain tissue, in transgenic models of the disease, and in culture [61]. A peptide, consisting of resi- dues 106–126 (PrP106-...

Ngày tải lên: 19/06/2014, 22:20

... Yoshida A, Ishibashi T: Induction of IL-8, MCP-1, and bFGF by TNF-alpha in retinal glial cells: implications for retinal neovascularization during post-ischemic inflammation. Graefes Arch Clin Exp ... apoptosis in this condi- tion [9]. However, TNF may also be directly involved in the formation of retinal NV in the later stages of the OIR model. In this study, we in...

Ngày tải lên: 19/06/2014, 22:20

... speed and symmetry. The training consisted of a 2-week treatment of 6 sessions. A visual biofeedback helped the subjects in maintaining a symmetrical contribution of the two legs during pedaling. ... were obtained by subtracting the mean tor- que computed during passive cycling from the torque profile calculated during each revolution of voluntary pedaling. In this way,...

Ngày tải lên: 19/06/2014, 08:20

... effects of con- ventional NSAIDs, which inhibit both isoforms of COX (constitutive and inducible). COX-2 is induced by pro- inflammatory stimuli and cytokines [25]. Inhibition of the inducible form ... DA quinones can deplete the cells of antioxidants, inactivate enzymes and increase α-synuclein protofibrils [56,63]. Induction of COX-2 results in an inflammatory casc...

Ngày tải lên: 19/06/2014, 22:20

... Qufu, Shandong, 273165, China Full list of author information is available at the end of the article Abstract In this paper, some new nonlinear delay integral inequalities on time scales are established, ... attention by many authors, and a lot of integral inequalities on time scales have been established (see [5-10] and the references therein), which are designed to unify con...

Ngày tải lên: 21/06/2014, 01:20