báo cáo hóa học:" BRCA1/2 genetic background-based therapeutic tailoring of human ovarian cancer: hope or reality?" ppt
Báo cáo hóa học: "Future research and therapeutic applications of human stem cells: general, regulatory, and bioethical aspects" ppt
... regulation for cell therapy products [117] include: i) demonstration of pre- clinical safety and efficacy; ii) no risk for donors of transmission of infectious or genetic diseases; iii) no risk for recipients ... characteristics of effi- cacy and saf ety of the new drugs based on this type of cells. Cell therapy is based on transplantation of live cells into an organism in o...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: "A randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ECOG 3899" pot
... established for the use of docetaxel chemotherapy [2]. An important mechanism of tumor resistance, which can be exploited therapeutically, is the over-expression of Bcl-2. The over-expression of Bcl-2 ... pain intensity and interference. Higher scores for BPI indicate worse pain or more interference; higher scores for the FACT and SCFS indicate better quality of life. Bcl-2 assess...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: " Quinolinic acid selectively induces apoptosis of human astrocytes: potential role in AIDS dementia complex" ppt
... competing interests. Authors' contributions GG was responsible for conception and planning of the experiments, for performing the immunocytochemical study and for writing of the manuscript. LW ... concentrations of QUIN. Numeration of apoptotic cells was assessed using double immunocytochemistry for expression of active caspase 3 and for nucleus condensation. We found that trea...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học: " Reflections on changeability versus stability of health-related quality of life: distinguishing between its environmental and genetic components" potx
... to poor quality of life and thus better target specific support and clinical man- agement interventions. The genetic information can be used to tailor individualized treatments for quality of life in ... important implications for theory, methods, and clinical practice. Implications for Theory The primary distinction of state and trait has an overarch- ing impact on the nomological ne...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học:" Species distribution and antimicrobial susceptibility of gram-negative aerobic bacteria in hospitalized cancer patients" pdf
... are potential markers for the presence of Extended-Spectrum β lactamases (ESβL). Aztreonam resistance is also a poten- tial marker for the presence of an ESβL-producing organ- ism. Levels of resistance ... coli (39% in case of leukemic patients, 33.3% in case of solid-tumor cancer patients) and Klebsiella pneumoniae (27.3% in case of leukemic patients, 47.6% in case of solid-tum...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" ApoG2 induces cell cycle arrest of nasopharyngeal carcinoma cells by suppressing the c-Myc signaling pathway" pot
... Administration approval of sorafenib and sunitinib, which target vascular endothelial growth factor receptor, platelet-derived growth factor receptor, FLT-3, and c-Kit, marks the use of a new generation of multitarget ... 1 State Key Laboratory of Oncology in South China and the Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou, PR China and 2 A...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Short-term cultured, interleukin-15 differentiated dendritic cells have potent immunostimulatory properties" ppt
... regulators of the human immune sys- tem, their use under the form of a cellular vaccine is an attractive strategy for the treatment of cancer and infec- tious diseases [3]. Since the results of the ... independent of the duration of culture (Table 2; IFN-γ short-term vs. long-term TLR-mDC: P = 0.17). The cytokine profile of IL-15 DCs was further explored by analyzing the relea...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: " HSF1 overexpression enhances oncolytic effect of replicative adenovirus" potx
... Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J Gen Virol 1977, 36:59-74. 11. Wu B, Hunt C, Morimoto R: Structure and expression of the human gene encoding major ... antitumoral efficacy of Adel55-cHSF1 in nude mice bearing Bcap37 or SW620 xenograft tumors. When tumor volumes reached about 30 mm 3 , mice were intratumorally in- jected...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Ezrin promotes invasion and metastasis of pancreatic cancer cells" ppt
... responsi- ble for RAC-dependent membrane ruffling downstream of the Ras signaling pathway [30]. It has been recentl y reported that phosphor ylation of e zrin is required for metastatic behavior of tumor ... any change of ezrin phosphorylation in either the ezrin over- expressing or the ezrin silencing MiaPaCa-2 cells. There- fore, phosphorylation of ezrin may not affect the motil...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " The “Excellence in Translational Medicine” and “Bedside-to-Bench” Awards 2008-09" pptx
... Badolato [4], recipient of the “Bedside-to-Bench Award 2008-09,” and co-workers of the University of Brescia (Brescia, Italy), poor adherence to prescriptions and the high rates of virus replication, ... Therefore, the need for improved correlates of immune reconstitution and early predictors of AR failure in HIV-infected children. Albeit, blood dendritic c ells constitute l ess t...
Ngày tải lên: 18/06/2014, 16:20