... [17]. Tremelimumab is a fully human IgG2 monoclonal antibody with high binding affinity for human CTLA-4 [18]. This anti- body is in late stages of clinical development in patients with metastatic melanoma ... Access Research CTLA4 blockade increases Th17 cells in patients with metastatic melanoma Erika von Euw 1 , Thinle Chodon 2 , Narsis Attar 2 , Jason Jalil 1 , Richard...
Ngày tải lên: 18/06/2014, 15:20
... statistical analyses and revised the manuscript critically. All authors read and approved the final manuscript. Additional material Acknowledgements We thank the members of the staff at the learning ... of the variables [54]. The patients included in this study were awaiting participation in a pulmonary rehabilitation programme, and were thus not a representative sample of all COPD...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: "Emotional and rational disease acceptance in patients with depression and alcohol addiction" doc
... Education and training help patients to develop living patterns that incorporate self-management. According to this informa- tive strategy, the patients learn about causes and sources, and what ... regarded as a coping style with an attitude of fatalistic resignation, but as a complex and active process of dealing with a chronic disease. One may assume that an emotional acceptan...
Ngày tải lên: 18/06/2014, 22:20
báo cáo hóa học: " Disability and quality of life in patients with fibromyalgia" doc
... unequal regarding the male/female ratio. In addition, although all patients had a chronic pain condition, patients with fibromyalgia and CLBP had pain for a longer period in comparison with CRPS patients. ... musculoskeletal pain: Evidence for an invariant two- factor model of the Tampa Scale for Kinesiophobia across pain diagnoses and Dutch, Swedish, and Canadian samples. Pa...
Ngày tải lên: 18/06/2014, 22:20
Báo cáo hóa học: " Dual task interference during gait in patients with unilateral vestibular disorders" ppt
... of aging as previously suggested [20]. The main finding was that patients demonstrated a significant worsening of back- ward counting during gait, compared to backward counting in single task ... head rotations while walking in dark was also demon- strated [9]. However, in our study, the between-groups Table 1 Gait parameters values in each task by group, mean ± standard deviation...
Ngày tải lên: 19/06/2014, 08:20
báo cáo hóa học: " Health-related quality of life in children with cystic fibrosis: validation of the German CFQ-R" potx
... with age appropriate versions [11-13]. It was originally devel- oped in France and then translated into several languages. Translation into German followed international recom- mendations and was ... fact that measures for HRQoL are not able to record all impacts of a disease on daily life, they allow investigations in large populations. Considering the advances in CF therapy and w...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " Replication of the association of HLA-B7 with Alzheimer''''s disease: a role for homozygosity?" pptx
... Lehmann* - donald.lehmann@pharm.ox.ac.uk; Martin CNM Barnardo - Martin.Barnardo@orh.nhs.uk; Susan Fuggle - Susan.Fuggle@nds.ox.ac.uk; Isabel Quiroga - isabelquiroga@hotmail.com; Andrew Sutherland ... beck@sanger.ac.uk; A David Smith - david.smith@pharm.ox.ac.uk * Corresponding author Abstract Background: There are reasons to expect an association with Alzheimer's disease (AD) wit...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học: " Does quality of life among breast cancer survivors one year after diagnosis differ depending on urban and non-urban residence? A comparative study" potx
... 2008. 2. Australian Institute of Health and Welfare (AIHW), Australasian Association of Cancer Registries (AACR): Cancer in Australia: An overview, 2006. Canberra: AIHW 2007. 3. Youlden D, Baade P, ... of Australia: Mapping Rural and Regional Oncology Services in Australia. COSA 2006. 13. NHMRC National Breast Cancer Centre: Clinical Practice Guidelines for the Management of Early Breast...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " Does angiotensin-1 converting enzyme genotype influence motor or cognitive development after pre-term birth?" docx
... (RAS), cleaves angiotensin I to yield the potent vasoconstrictor angi- otensin II. In addition, ACE degrades vasodilator kinins. In these ways, endocrine RAS plays an important role in circulatory ... 'D' allele) of a 284-base-pair fragment in the human ACE gene is associ- ated with lower ACE activity in organs including both cir- culating inflammatory cells [11] and t...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học:" Molecular Etiology of Hearing Impairment in Inner Mongolia: mutations in SLC26A4 gene and relevant phenotype analysis" ppt
... different populations a Chinese a Chinese a Taiwanese a Korean a Japanese a French a Caucasian European a US a Total number of patients 135 NSHI (20 EVA) 95 EVA 38 EVA 26 EVA 10 PS + 32 EVA 30 PS ... including 22 patients carrying bi-allelic GJB2 mutations or one patient carrying a known GJB2 dominant mutation as well as one patient with mtDNA 155 5A& gt;G mutati...
Ngày tải lên: 18/06/2014, 15:20