báo cáo hóa học:" ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function" pptx

... Translational Medicine Open Access Research Cyclic changes in gene expression induced by Peg-interferon alfa-2b plus ribavirin in peripheral blood monocytes (PBMC) of hepatitis C patients during the first ... relapsed by the end of treatment. Changes in Global Gene Expression Gene expression in PBMC changed dramatically and rap- idly during PEG-in...

Ngày tải lên: 18/06/2014, 15:20

... hepatic cancer, colon cancer and lung cancer. Immunostaining of prostate cancer tissue with antibodies against AMACR and PSAFigure 2 Immunostaining of prostate cancer tissue with antibodies against ... mRNA in prostate cancer line LNCaP, but only very weak expression of AMACR mRNA was observed in normal adult liver and pancreas (Figure 1A) . In contrast, t...

Ngày tải lên: 18/06/2014, 15:20

... tumor calculated in the present series was 18.72. It is interest- ing to note that for the bilateral borderline ovarian tumors the ANCA index was 24.5 whereas for the uni- lateral borderline ovarian tumors ... rominently in both overt carcinomas [37,50] and in the present series (the gains were found in 5 of 5 cases with bilateral borderl ine tumors and in 4 of 6 informative...

Ngày tải lên: 18/06/2014, 16:20

... capable of phagocytosing myelin and damaging axons. In this study, we characterize the regional, temporal and cellular expression of CCR1, CCR2 and CCR5 mRNA in the spinal cord of rats with myelin ... inflammatory activity and demyelination, as previously described by Brück et al [36]. Distribution of CCR1, CCR2 and CCR5 mRNA in the rat spinal...

Ngày tải lên: 19/06/2014, 22:20

... soon. Innate Immunity in multiple sclerosis white matter lesions: expression of natural cytotoxicity triggering receptor 1 (NCR1) Journal of Neuroinflammation 2 012 , 9 :1 doi :10 .11 86 /17 42-2094-9 -1 Pascal ... transformation in mouse and human. J Clin Invest 2 011 , 12 1 :14 56 -14 70. 37. Spits H, Di Santo JP: The expanding family of innate lym...

Ngày tải lên: 19/06/2014, 22:20

... real-time quantification RT-PCR detection of type X collagen mRNA Gene Primer Sequence Type X collagen Forward 5'-AGTGCTGTCATTGATCTCATGGA-3' Reverse 5'-TCAGAGGAATAGAGACCATTGGATT-3' 18S ... Orthopaedic Surgery and Research Open Access Research article Differential expression of type X collagen in a mechanically active 3-D chondrocyte...

Ngày tải lên: 20/06/2014, 00:20

... that transient expression of an antiviral hairpin RNA by A. tumefaciens results in resist- ance to PVY transmission by aphids. Several studies have Detection of PVY CP and PVY small interfering RNAs ... PVY transmission exhib- ited by transiently expressed IRCPPVY could reflect any kind of unspecific, defence response of plants elicited by hairpin RNA s...

Ngày tải lên: 20/06/2014, 01:20

... Research Open Access Research ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function Daniel R Christie 1 , Faheem M Shaikh 2 , ... a change in receptor conformation, by masking functional domains within the integrin heterodimer, by affecting integrin interaction with other membrane boun...

Ngày tải lên: 20/06/2014, 07:20

... CCR9 interactions support ovarian cancer cell survival and resistance to cisplatin-induced apoptosis in a PI3K-depen- dent and FAK-independent fashion Journal of Ovarian Research 2010, 3:15 Received: ... and reproduction in any medium, provided the original work is properly cited. Research CCR9 interactions support ovarian cancer cell surviva...

Ngày tải lên: 20/06/2014, 07:20

... localization of ALDH1 in normal ovaries. [A-B] Intens e staining of numerous cells of stroma (S) and surface epithelial cells (SE) was observed in normal ovary. Insets showing examples of ALDH1 stained ... apoptosis in various cell types including ovary [12-17]. In ovarian cancer the expression of the retinol binding proteins involved in RA metabolism is reduc...

Ngày tải lên: 20/06/2014, 07:20

... suggesting b1integrinhasaroleinmediating these changes. Intriguingly, these changes in protein level are not reflected at the RNA level, indicating that the effect of HOXA4 on b1 integrin and ... [17-20]. Function of HOX genes in ovarian cancer Tumour Growth In addition to phenotypic determination, HOX genes are thought to play a role in the oncogenesis of ovarian can- cer...

Ngày tải lên: 20/06/2014, 08:20

... suffers from one or more respiratory symptoms [4,5]. Respiratory symptoms are important markers of the risk of having or developing disease. Respiratory symptoms have been shown to be predictors ... respiratory symptoms are important determinants of reduced health related quality of life (HRQoL) [12-15]. The prevalence of respiratory symptoms ex...

Ngày tải lên: 20/06/2014, 16:20

... (H31 0A) antibody of diff erent tissue specimens.At×40 magnification, (a) human pancreas cancer with strong staining, (b) human pancreas cancer with moderate staining, (c) human pancreas cancer with ... ORIGINAL RESEARCH Open Access Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment Mark D Girgis 1,3 , Tove Olafsen 2...

Ngày tải lên: 20/06/2014, 22:20