... Because of inconclusive results in the litera- ture regarding variables that predict HRQL in colorectal patients, we adopted an exploratory approach and evalu- ated a large number of variables, ... did using standard statistical tests for continuous and categorical data. All candidate predictor variables for the longitudinal analyses were measured either at the time of diagnosis or dur...
Ngày tải lên: 18/06/2014, 19:20
... psoriasis. Methods: Data were obtained for a secondary analysis of patients in a randomized, controlled Phase III trial evaluating the effect of adalimumab in patients with psoriasis (N = 1,205). Patients ... for patients with moderate to severe plaque psoriasis. Background: Psoriasis is a chronic, inflammatory, immune-mediated disease that has a significant impact on p...
Ngày tải lên: 18/06/2014, 19:20
Báo cáo hóa học: " Audio-Biofeedback training for posture and balance in Patients with Parkinson’s disease" doc
... balance and postural control. Average, stan- dard deviations and ranges were extracted as well as the percent change after training and at follow up from the initial baseline evaluation. Training ... continuously adjusting and challenging the patient. The rational for this training program was b ased on motor learni ng paradigms aimed at providing demanding tasks for the patient and allow- in...
Ngày tải lên: 19/06/2014, 08:20
báo cáo hóa học:" Whole blood assessment of antigen specific cellular immune response by real time quantitative PCR: a versatile monitoring and discovery tool" potx
... 163:6867-6875. 9. Kammula US, Marincola FM, Rosenberg SA: Real-time quantita- tive polymerase chain reaction assessment of immune reac- tivity in melanoma patients after tumor peptide vaccination. J Natl Cancer ... specific or a control (Melan -A/ MART-1 27–35 ) peptide at a 10 μg/ml concentration. Following 5 hour incubation at 37°C, RNAlater was added to the sam- ples and total...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Mass spectrometry-based serum proteome pattern analysis in molecular diagnostics of early stage breast cancer" pdf
... Polanska †3 , Katarzyna Behrendt 1 , Elzbieta Nowicka 1 , Anna Walaszczyk 1 , Aleksandra Chmura 1 , Regina Deja 1 , Maciej Stobiecki 2 , Andrzej Polanski 3,4 , Rafal Tarnawski 1 and Piotr Widlak* 1 Address: ... corre- sponding signal abundances, covering the range of ana- lyzed m/z values. Analysis of protein tumor markers in plasma Plasma samples were obtained after centrifugation of b...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: " Comparison of T-cell receptor repertoire restriction in blood and tumor tissue of colorectal cancer patients" docx
... beta gene usage in skin cancer. J Invest Dermatol 1994, 103:751-7. 32. Chikamatsu K, Eura M, Nakano K, Kanzaki Y, Matsuoka H, Masuyama K, Ishikawa T: Analysis of T cell receptor variability in ... Caignard A: In vivo local expansion of clonal T cell subpopulations in renal cell carcinoma. Cancer Res 1995, 55:685-90. 35. Mouri T, Nakamura S, Ohyama Y, Matsuzaki G, Shinohara M, Kish...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Epidermal growth factor receptor gene copy number in 101 advanced colorectal cancer patients treated with chemotherapy plus cetuximab" doc
... primer (5'-AGGCCTGCTGAA AATGACT- GAATA-3'), 10 pmol K-ras antisense primer (5'-CTG- TATCAAAGAATGGTCCTGCAC-3'), and 1 U of Taq polymerase (Resnova). An additional no-template control containing ... RM: FISH analysis. IS: statistical analysis. EM: DNA extraction and k-ras mutation analysis. SC: DNA extraction and k-ras mutation analysis. MGD: patho- logical sample evaluation...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Adenoviruses with an avb integrin targeting moiety in the fiber shaft or the HI-loop increase tumor specificity without compromising antitumor efficacy in magnetic resonance imaging of colorectal cancer metastases" pdf
... domain in the fiber shaft has been suggested to play a major role in viral internalization via low affinity binding with HSPG [ 27-29] and a mutatio n in this domain has been shown to decrease ... Rowinsky EK, et al: Phase I, pharmacokinetic, and pharmacodynamic study of intravenously administered Ad5CMV-p53, an adenoviral vector containing the wild- type p53 gene, in patients w...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " cDNA targets improve whole blood gene expression profiling and enhance detection of pharmocodynamic biomarkers: a quantitative platform analysis" ppt
... participated in the analysis of the SAHA data and participated in the drafting and editing of the manuscript. All authors read and approved the final manuscript. Competing interests All authors were ... arrays (see above) following the vendor’ s recommended protocols. Data processing and analysis Microarray data quality was assessed using standard metrics [26]. RMA was used for data nor...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Prognostic significance of Oct4 and Sox2 expression in hypopharyngeal squamous cell carcinoma''''" doc
... posits that tumors may be initiated and maintained by a subset of cells that maintain or acquire stem-cell properties and that each tumor contains a small subpopulation of cells that have the ability ... lified in a stepwise fashion by removing variables that had a p value ≥0.05. Only three variables remained statistically significant as independent predictors of OS and LRC in the...
Ngày tải lên: 18/06/2014, 16:20