... immunotoxic- ity of TGN1412: a) there was a concordance in the cytok- ines induced in humans in vivo and in vitro, and b) the cytokine storm-associated response was not observed either in vivo or in vitro in ... further below the threshold. This rank of Ab-01 at the bottom of the list in terms of responses to immunoglobulin reagents in the in vitro cros...
Ngày tải lên: 18/06/2014, 16:20
... point in assessing treatment effectiveness. Recent studies have examined the role of distress or bother in assessing the impact of UI on HRQoL in com- munity dwelling women, in part to begin ... [20], the Incontinence Severity Index (ISS) [21] and the BFLUTS [22]. Instruments that examined QoL impact of urinary incontinence were the Incontinence QoL questionnaire (...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: "Single-trial classification of NIRS signals during emotional induction tasks: towards a corporeal machine interface" pptx
... component in the image. The PFC is involved in maintaining attentional demand [50], and variations in intensity and latency of hemodynamic activity across individuals might be caused by the different ... aspects of the study as physically tiring. Incorporation of on-line feedback into the experiment may help maintain the par- ticipant's concentration and improve...
Ngày tải lên: 19/06/2014, 08:20
báo cáo hóa học: " β-Amyloid promotes accumulation of lipid peroxides by inhibiting CD36-mediated clearance of oxidized lipoproteins" pot
... assess the role of CD36 and CD36/SRA-independent pathways. In the absence of CD36, oxLDL binding was not reduced by Aβ, indicating that this receptor is the target of Aβ inhibition. Binding of ... not inhibited by Aβ, assesed 125 I-oxLDL binding in Sra -/- Cd36 -/- macro- phages. No effect of Aβ was observed in these cells, dem- onstrating the specificity of...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học: " Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression" docx
... 4 Inflammatory parameters in brain cort ex after CMS. Protein expressi on of COX-2 in control and after CMS in the brain (A). Brain levels of the pro-inflammatory prostaglandin PGE 2 (B), the ... 8:151 http://www.jneuroinflammation.com/content/8/1/151 Page 11 of 14 production [46,47]. The induction of COX-2 in the CNS by stress and the increase in the PGE 2 l...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học:" Assessing the clinical utility of measuring Insulin-like Growth Factor Binding Proteins in tissues and sera of melanoma patients" potx
... purposes) Journal of Translational Medicine Open Access Research Assessing the clinical utility of measuring Insulin-like Growth Factor Binding Proteins in tissues and sera of melanoma patients Jessie ... receptor; (IGFBP-3): Insulin-like Growth Factor Binding Protein-3; (IGFBP-4): Insulin-like Growth Factor Binding; Protein-4; (MAPK): Mitogen-activated protein kinase; (IMCG): In...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học: " Assessing the empirical validity of alternative multi-attribute utility measures in the maternity context" potx
... widely applied in the broader health-related quality of life literature [35-40]. It is defined as the ratio of the square of the t-statistic of the comparator instrument (assumed to be the SF-6D utility score ... [20]. The main focus of the study centred on the empirical validity of the utility scores generated by the EQ-5D and SF-6D. Given the absence...
Ngày tải lên: 18/06/2014, 18:20
báo cáo hóa học:" Anti-angiogenic effect of high doses of ascorbic acid" pptx
... detection, cells were incubated in PBS with 10 mM glucose containing 5 μM DAF-FM-DA for 30 min at 37°C. After the incubation, cells were washed and incubated in the presence of either: inhibitors, stimu- lators, ... proportional to the amount of ATP present in the cells. The amount of ATP produced was determined from a standard curve by measuring the level of lumin...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Whole blood assessment of antigen specific cellular immune response by real time quantitative PCR: a versatile monitoring and discovery tool" potx
... responses in large groups of vaccinated individuals. On the other hand, the power of this method as discovery tool should also be underlined. Our data document for the first time that in vaccinated individuals ... panel A), thus ruling out the possibility of a prevailing allospe- cific responsiveness from host WB T cells. In line with these data, the extent of the in...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells" pptx
... upregulation of genes involved in reverse cholesterol transport (RCT), including ABCA1 and ABCG1 transporters, in macrophage and intestine. Anti- atherosclerotic effects of synthetic LXR agonists in murine ... in washing buffer (PBS, 0.1% Tween20). To determine the equivalence of protein loading between samples, actin protein in each sample was detected by Western blotti...
Ngày tải lên: 18/06/2014, 15:20