... decreased the percentage of cells in S phase and increased the percentage of cells in the G0/G1 phase, indicating a cell cycle arrest at the G1-S checkpoint. The percentage of cells in G0/G1 phase increases ... MAM assisted in conception of study and aided in the drafting of the manuscript. JMD coordinated the study and provided funding of the stud- ie...
Ngày tải lên: 20/06/2014, 07:20
... (corresponding to the increase of the velocity), which causes the nanofluid to rotate mainly around the inside wall of the square cav- ity. In addition, it can be seen that the temperature iso- therms become ... Technology, Harbin 150001, China 2 Institute of Particle Science and Engineering, University of Leeds, Leeds LS2 9JT, UK Authors’ contributions YRH conceived of...
Ngày tải lên: 21/06/2014, 05:20
báo cáo hóa học:" A novel role of HLA class I in the pathology of medulloblastoma" docx
... to the combined epitope contributed by the α2 and α3 domains of the heavy chain and β2m, dependent on the presence of pep- tides in the peptide-binding groove [40-42]. The levels of open conformers ... Beta2- microglobulin promotes the growth of human renal cell car- cinoma through the activation of the protein kinase A, cyclic AMP-responsive element-binding prot...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: "TAp73 is one of the genes responsible for the lack of response to chemotherapy depending on B-Raf mutational status" pot
... involved in the lack of response to oxaliplatin in monotherapy or combined with cetuximab. Background The incidence of colorectal cancer has been increasing in the last few years, while the age of ... [1]. The advances in the treatment of this disease include studies of single- agen ts vs. combination treatment with 5-FU/leucovorin, irinotecan, oxal iplatin, and...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " An exploratory investigation of the influence of publication on translational medicine research" pot
... Cree Abstract Background: Changes in clinical practice are brought about by the weight of clinical evidence for and against an intervention. Clinical evidence of efficacy relies on the dissemination of research results, ... modelling. The challenge is to ensure that the benefits of translational research are delivered as changes in clinical practice. Changes in...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: " A psychometric evaluation of the PedsQL™ Family Impact Module in parents of children with sickle cell disease" pptx
... mild disease. The Institutional Review Board of the Children's Hospital of Wisconsin/Medical College of Wisconsin approved the study and informed consent was obtained from the par- ents. Outcome ... limitations should be considered in evaluat- ing these study results. The parents were involved in the study during a routine clinic visit and so the reported scores a...
Ngày tải lên: 18/06/2014, 18:20
báo cáo hóa học: " Development and validation of the Treatment Related Impact Measure of Weight (TRIM-Weight)" pdf
... 8:19 http://www.hqlo.com/content/8/1/19 Page 3 of 11 based approach. Since longitudinal data are not being used, one must be cautious in the interpretation of the results in relation to minimally important differences. As these findings ... structure, using 0.40 as the minimum factor loading to be eligible as an i tem for a giv en fac- tor, as well as taking into consideration...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " Cross-diagnostic validity of the Nottingham health profile index of distress (NHPD)" doc
... disability in patients with arthrosis of the hip joint. Reliability of the Swedish version of the Nottingham Health Profile. Int Disabil Stud 1988, 10(4):159-163. 35. Andrich D, Sheridan B, Luo G: Interpreting ... with the model, Rasch derived measures have the same meaning throughout the range of measurement and the relative locations of any two items (or persons) a...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " Internal construct validity of the Warwick-Edinburgh Mental Well-being Scale (WEMWBS): a Rasch analysis using data from the Scottish Health Education Population Survey" potx
... where missing values are present. However, the precision of the estimate is reduced to an extent depending on the number of missing items. The Rasch model In satisfying the axioms of conjoint measurement ... Alpha [10]. In order to obtain robust estimates of the internal con- struct validity of the scale, the total data set is randomised into two further sets of...
Ngày tải lên: 18/06/2014, 19:20