báo cáo hóa học:" Perioperative safety of two-team simultaneous bilateral total knee arthroplasty in the obese patient" docx

Báo cáo hóa học: "Prognostic impact of clinical course-specific mRNA expression profiles in the serum of perioperative patients with esophageal cancer in the ICU: a case control study" potx

Báo cáo hóa học: "Prognostic impact of clinical course-specific mRNA expression profiles in the serum of perioperative patients with esophageal cancer in the ICU: a case control study" potx

... Depiction of the diagnostic accuracy of CRP and mRNA levels. (a) Change in circulating CRP mRNA expression during the clinical course in ICU. Upregulation of CRP mRNA was induced at POD 1 by the surgical ... prognostic indica- tor in fulminant hepatitis in patients without encephalo- pathy upon a dmission [10,11]. In the present study, we examined 11 proinflammatory ge...
Ngày tải lên : 18/06/2014, 16:20
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báo cáo hóa học:" Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines" pptx

báo cáo hóa học:" Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines" pptx

... combination with chemotherapy The effect of dasatinib in combination with chemother- apy was examined in the three dasatinib responsive cell lines, Lox-IMVI, HT144 and Malme-3M and in one of the dasatinib-resistant ... in melanoma and other solid tumours. The in vitro effects of dasatinib in melanoma cell lines observed in this study provide strong evidence for eva...
Ngày tải lên : 18/06/2014, 15:20
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Báo cáo hóa học: " Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032" potx

Báo cáo hóa học: " Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032" potx

... tested the anti-tumor effects of a specific inhibitor of Raf protein kinases, PLX4032/RG7204, in melanoma cell lines. PLX4032 decreased signaling through the MAPK pathway only in cell lines with the ... baseline pAkt detectable in M233 but not M229, as well as increase in pAkt upon PLX4032-expo- sure in the resistant M233 but not in the sensitive M229 cell line. In...
Ngày tải lên : 18/06/2014, 16:20
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Báo cáo hóa học: "High activity of sequential low dose chemo-modulating Temozolomide in combination with Fotemustine in metastatic melanoma. A feasibility study" pptx

Báo cáo hóa học: "High activity of sequential low dose chemo-modulating Temozolomide in combination with Fotemustine in metastatic melanoma. A feasibility study" pptx

... carried out the coordination of the study and drafted the manuscript. All authors read and approved the final manuscript. Competing interests The authors declare that they have no competing interests. Received: ... of tumoral associated antigens. Regarding the toxic profile, there was a signi ficant dif- ference between the two cohorts of patients, principally in terms...
Ngày tải lên : 18/06/2014, 16:20
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báo cáo hóa học: "New method of measuring wrist joint position sense avoiding cutaneous and visual inputs" docx

báo cáo hóa học: "New method of measuring wrist joint position sense avoiding cutaneous and visual inputs" docx

... have occurred at the metacarpophalangeal and interphalan- geal joints during passive movement of the wrist joint via the manipulandum. In addition, the tubular dressing placed on the fingers could ... sub- jects reproducing the extent of motion rather than joint position. Regardless of the starting position, a minimum excursion of 20° was used for all trials. All the...
Ngày tải lên : 19/06/2014, 08:20
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Báo cáo khoa học: Molecular characterization of Osh6p, an oxysterol binding protein homolog in the yeast Saccharomyces cerevisiae pot

Báo cáo khoa học: Molecular characterization of Osh6p, an oxysterol binding protein homolog in the yeast Saccharomyces cerevisiae pot

... pro- tein–protein interaction. In this study, Osh6p was demonstrated to bind a pool of phosphatidylinositol phosphates (PtdInsP) including PtdIns(4)P, PtdIns(5)P, PtdIns(3,4)P 2 and PtdIns(3,5)P 2 with ... As shown in Fig. 7, at 0 min of chase, p1 CPY was the predominant form. The p2 form was seen at the 5 min time point. At a later time (10 min), mature CPY was observed togethe...
Ngày tải lên : 07/03/2014, 21:20
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Báo cáo khoa học: Identification of a novel inner-core oligosaccharide structure in Neisseria meningitidis lipopolysaccharide docx

Báo cáo khoa học: Identification of a novel inner-core oligosaccharide structure in Neisseria meningitidis lipopolysaccharide docx

... with the observed differences in the NOE contacts for the Glc I to Hep I linkage. In all three strains examined, in which the Hep I residue of the LPS bears the additional Glc II residue at the ... except that in the meningococcal strains investigated here it is a glucose residue at the 2 position. It is intriguing that only a small number of the meningococcal...
Ngày tải lên : 08/03/2014, 02:20
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Báo cáo Y học: Functional integration of mitochondrial and hydrogenosomal ADP/ATP carriers in the Escherichia coli membrane reveals different biochemical characteristics for plants, mammals and anaerobic chytrids pdf

Báo cáo Y học: Functional integration of mitochondrial and hydrogenosomal ADP/ATP carriers in the Escherichia coli membrane reveals different biochemical characteristics for plants, mammals and anaerobic chytrids pdf

... exhibited the lowest expression level. Furthermore, Western blot analyses of purified membranes of the induced E. coli cells using an anti-His Ig have corroborated the integration of the AACs into the ... preloaded with either ADP or ATP. If a counter exchange mechanism is maintained in induced E. coli cells, then the export of adenylates by the recombinant AACs must de...
Ngày tải lên : 18/03/2014, 01:20
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Báo cáo khoa học: Differential involvement of protein kinase C alpha and epsilon in the regulated secretion of soluble amyloid precursor protein docx

Báo cáo khoa học: Differential involvement of protein kinase C alpha and epsilon in the regulated secretion of soluble amyloid precursor protein docx

... data in the literature that indicate PKCe as the only protein kinase isoform involved in the s ignalling pathway downstream of muscarinic m3 receptors in SK-N-BE(C) neuroblasto ma cells [15]. The Ó ... PKCe in the r egulated processing of APP. There is substantial evidence in the literature for a significant role of PKCe both in the regulation of APP metabolis...
Ngày tải lên : 23/03/2014, 13:20
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Báo cáo khoa học: Co-operation of domain-binding and calcium-binding sites in the activation of gelsolin pptx

Báo cáo khoa học: Co-operation of domain-binding and calcium-binding sites in the activation of gelsolin pptx

... 203–225, including one of the actin-binding sites, is in interaction with the C-terminal a-helix of G6 domain. The sequence 159–193, including the second actin interface, appears also in interaction ... to G2 domain. Footprint of G2 on gelsolin G4–6 domain Two sites within the G2 domain appear involved in the G2- G4–6 interface in the presence of EGTA (Fig. 3)....
Ngày tải lên : 31/03/2014, 01:20
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