... study and from previous ones on the role of CCR1 and its ligandCCL3 in the pathogenesis of MS [39,40,42] and EAE[22,44,46], have provided evidence for an important role of CCR1 in MS and EAE.Histopathological ... inflammation and demyelination (Fig. 2E).During the clinical remission phase (day 18), inflamma-tion and demyelination in the spinal cord were consider-ably diminished (Fig. 3G, 3I) and the number of infiltrating ... expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAESana Eltayeb1, Anna-Lena Berg*2, Hans Lassmann3,...