báo cáo hóa học:" Importance of disulphide bonds for vaccinia virus L1R protein function" docx

... (pfu/ml)pL1RC34/49SC34/57SC34/116SC34/136SC34/158SC49/57SC49/116SC49/136SC49/158SC57/116SC57/136SC57/158SC116/136SC116/158SC136/158S1.0×1041.0×1051.0×1061.0×1071.0×108 Virus Titer (pfu/ml)A)B)C)BioMed CentralPage 1 of 5(page number not for citation purposes)Virology JournalOpen AccessShort report Importance of disulphide bonds for vaccinia virus L1R ... suggest that protein disulphide isomerases may be involved in reorganization of disulfide bonds within the L1R protein. Findings Vaccinia virus (VV) continues to be the model organism for the investigation ... encoded protein disulphide isomerase is required for proper disulphide pairing in active L1R. It is conceiva-ble that cyteine-57 forms an incorrect disulphide pairingas an intermediate. Protein disulphide...

Báo cáo sinh học: "Importance of disulphide bonds for vaccinia virus L1R protein function" pot

... membrane of the ERGIC, the bonds are isomer-BioMed CentralPage 1 of 5(page number not for citation purposes)Virology JournalOpen AccessShort report Importance of disulphide bonds for vaccinia virus ... encoded protein disulphide isomerase is required for proper disulphide pairing in active L1R. It is conceiva-ble that cyteine-57 forms an incorrect disulphide pairingas an intermediate. Protein disulphide ... solely in the lumen of the ER.This study has shown that only two of the three intramo-lecular disulphide bonds are essential for L1R to performits function in formation of infectious IMV particles.Cysteine...

Báo cáo hóa học: " Effect of Interfacial Bonds on the Morphology of InAs QDs Grown on GaAs (311) B and (100) Substrates" potx

... emission of InAs QD laser around 1.3 lm for the ﬁber opticalcommunication waveband [3] and optical absorption at8–12 lm for the long-wavelength infrared detecting [4]had been achieved by means of ... andgrowth dynamic of InAs QDs grown on the alloy layer are of central importance. And much attention has been paid tothese important research ﬁelds [5–7].However, most of the studies focused ... their efforts inimproving the device performances. However, the growthmechanism of QDs is still a controversial subject, espe-cially with regard to the high index surfaces. Apparently, for the...

báo cáo hóa học:" Development of targeted therapy for ovarian cancer mediated by a plasmid expressing diphtheria toxin under the control of H19 regulatory sequences" doc

... described [24]Determination of the level of RNA products of the H19 geneThe PCR reactions were carried out in 25 μl volumes in thepresence of 6 ng/μl of each of the forward and the reverseprimers ... prep-aration).ConclusionOn the basis of this study we formed a platform for thedesign of an extensive phase I study on a larger number of human patients to test the safety of this treatment.The results obtained ... work shows the use of the regulatorysequences of the H19 gene for the development of DNA-based therapy for human ovarian cancer related ascites.The successful development of anti-tumor gene...

Báo cáo hóa học: " Evaluation of normalization methods for two-channel microRNA microarrays" ppt

... is possible for the estimated ICC to benegative due to use of method -of- moments estimation,especially when the number of technical replicates issmall. The advantage of the method -of- moments ... 8:69http://www.translational-medicine.com/content/8/1/69Page 3 of 7file 1, 2]. With the exception of the lowess metho dbased on 10% invariant set, performing some type of normalization produced a higher ICC than performingno normalization ... invariant setalso performed well for the renal cancer cell line s, butaverage observed ICCs were slightly higher for globalmedian and mean methods. The good performance of quantile normalization...

Báo cáo hóa học: " Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences" potx

... tumors treated with: 25 μg of H19-DTA, 25 μg of P4-DTA, 25 μg of H19-DTA + 25 μg of P4-DTA 25 μgofH19-DTA-P4-DTA and 50 μg of H19-DTA-P4-DTA.Amit and Hochberg Journal of Translational Medicine ... 94°C for 30 sec, 59°C for 45 sec and 72°C for 60 sec, and finally 72°C for 5 min.The PCR reactions were carried out in 25 μlvolumesinthepresenceof6ng/μl of each of the forward and thereverse ... carefully. Samples of thetumors were fixed in 4% buffered formaldehyde andprocessed for histological examination for evidence of necrosis and persistent tumor. Computerized measure-ments of tumor surface...

báo cáo hóa học: " Validation of the Clinical COPD Questionnaire (CCQ) in primary care" docx

... potential conflicts of interest related to the subject of the manuscript exist for any of the authors.References1. Global Strategy for the Diagnosis, Management and Preven-tion of Chronic Obstructive ... Quality of Life Outcomes 2009, 7:26 http://www.hqlo.com/content/7/1/26Page 2 of 9(page number not for citation purposes)Extensive questionnaires for research purposes providevaluable information, ... analyses were performed for the entire study samplewith clinical COPD (n = 111) and for the subgroup of patients with spirometry verified COPD (n = 83) whichwere the major part of the study population....

Báo cáo hóa học: " Validity of gait parameters for hip flexor contracture in patients with cerebral palsy" pot

... hipmusculature. J Biomech 1981, 14:803-812.3. Feldkamp M, Denker P: Importance of the iliopsoas muscle in soft-tissuesurgery of hip deformities in cerebral palsy children. Arch Orthop TraumaSurg ... gaitparameters of the patients, includin g gender, age,GMFCS level, cadence, step length, and walking speed,were collected. Informed consent for the retrospectivereview of the gait analy sis data of patients ... 2009,29:251-255.5. Matsuo T, Hara H, Tada S: Selective lengthening of the psoas and rectusfemoris and preservation of the iliacus for flexion deformity of the hipin cerebral palsy patients. J Pediatr Orthop...

Báo cáo hóa học: " Effects of obesity and chronic low back pain on gait" docx

... Move-ment Analysis Lab of our Institu te using an optoelectro-nic system with 6 cameras (460 VICON, Oxford MetricsLtd., Oxford, UK) with a sampling rate of 100 Hz, andtwo force platforms (Kistler, ... ends at toe-off of the same limb;Double stance phase (%gait cycle)% of gait cycle when both feet are on the groundMean velocity (1/s) mean velocity of progression normalised for individual ... position of knee joint at the beginning of gait cycleKmSt minimum of knee flexion (knee position on sagittal plane) in mid-stance, representing the extension ability of kneeduring this phase of gait...

Báo cáo hóa học: " Comparison of regression models for estimation of isometric wrist joint torques using surface electromyography" potx

... Half of the summation of PCSA values for non-primaryflexors was added to each of the two primary flexorswhile a third of the summation of PCSA values for non-primary extensors ... networksforestimationofthumb-tipforcesunderfourdifferentconfigurations. In another study, performance of a Hill-based physiological muscle model was compared to aneural network for estimation of forearm ... witnessed for forces of up to30% of the maximum isometric force [33]. These non-linear relationships can be associated with exponentialincreases in firing rate of motor units as muscle forcesincrease...

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