báo cáo hóa học:" Replicative homeostasis II: Influence of polymerase fidelity on RNA virus quasispecies biology: Implications for immune recognition, viral autoimmunity and other "virus receptor" diseases" doc
báo cáo hóa học:" Replicative homeostasis II: Influence of polymerase fidelity on RNA virus quasispecies biology: Implications for immune recognition, viral autoimmunity and other "virus receptor" diseases" doc
... JournalOpen AccessHypothesis Replicative homeostasis II: Influence of polymerase fidelity on RNA virus quasispecies biology: Implications for immune recognition, viral autoimmunity and other ... diversity and immune recognition under influence of Replicative homeostasisFigure 7Conceptual progression of intracellular viral replication events, including variable RNA pol fidelity and processivity, ... processivity, restriction of antigenic diversity and immune recognition under influence of Replicative homeostasis. Panels (A->E) changing frequency distri-bution of viral RNA and protein quasispecies, ...
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Báo cáo sinh học: " Replicative homeostasis II: Influence of polymerase fidelity on RNA virus quasispecies biology: Implications for immune recognition, viral autoimmunity and other "virus receptor" diseases" pot
... CentralPage 1 of 20(page number not for citation purposes)Virology JournalOpen AccessHypothesis Replicative homeostasis II: Influence of polymerase fidelity on RNA virus quasispecies biology: Implications ... variable RNA pol fidelity and processivity, restriction of antigenic diversity and immune recognition under influence of Replicative homeostasisFigure 7Conceptual progression of intracellular viral ... genera-tion of RNA quasispecies by RNA pol, and translation of these immensely variable RNAs into protein quasispecies, suggests an immediate solution to the problem of viral autoimmunity and, by...
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báo cáo hóa học:" Replicative Homeostasis: A fundamental mechanism mediating selective viral replication and escape mutation" ppt
... number not for citation purposes)a. Constraints on viral mutationFigure 3a. Constraints on viral mutation. Inadequate polymerase fidelity will cause loss of sequence information and quasispcies ... accumulation of variant viral proteins causes progressive, direct, inhibition of RNA pol and also block EnvWt :RNA pol interactions that increasereplication and mutation. Progressive blockade of RNA polby ... phenomenon probably respon-sible for attenuation of virulence of serially passaged virus cultures. By contrast, in dilute viral culture, where viral envelope and polymerase exist in low concentrations,high...
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Báo cáo hóa học: "Multicenter phase II study of matured dendritic cells pulsed with melanoma cell line lysates in patients with advanced melanoma" potx
... clearcorrelation between results of immune monitoring and clinical benefit in terms of tumor responses. This lack of correlation of immune parameters and response mayrelate to the likely low sensitivity of ... rol(objective responses by RECIST plus SD beyond 8weeks)rateof20%,anullresponserateof5%,atypeone error of 0. 10, and a type two error of 0.10. As such,continuation to the second stage required one patientoutofthefirst12recruitedtodemonstratepositivetumor ... significantregression of cutaneous lesions (concomitant changes inpigmentation and nodularity) with continued dosing.Resection of two nodules at weeks 24 and 36 showed noevidence of viable melanoma;...
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báo cáo hóa học:" Salter-Harris II injury of the proximal tibial epiphysis with both vascular compromise and compartment syndrome: a case report" docx
... degrees of flexion) and open reduction and internal fixation of displaced type III, IV and V. Someauthors regret not fixing type I and II fractures, withsubsequent loss of reduction and unsatisfactory ... months post-operative radiographs.Journal of Orthopaedic Surgery and Research 2009, 4:23 http://www.josr-online.com/content/4/1/23Page 2 of 5(page number n ot for citation purposes)A common ... here:http://www.biomedcentral.com/info/publishing_adv.aspBioMedcentralJournal of Orthopaedic Surgery and Research 2009, 4:23 http://www.josr-online.com/content/4/1/23Page 5 of 5(page number n ot for citation purposes)Authors' contributionsAG was...
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báo cáo hóa học: "The New Jersey Institute of Technology Robot-Assisted Virtual Rehabilitation (NJIT-RAVR) system for children with cerebral palsy: a feasibility study " docx
... attention in 2 of the 4 sessions with this simu-lation and fatigue in 3 of the 4 sessions. S2 demonstrateddecreased attention during three of his 4 sessions and fatigue during 4 of his sessions ... simulation with no attention lapses, nodemonstrations of fatigue and unanimous agreement thatthe simulation was fun and an option for future sessions.The other simulations did not display a consistentresponse ... Journal of NeuroEngineering and Rehabilitation 2009, 6:40 http://www.jneuroengrehab.com/content/6/1/40Page 3 of 10(page number not for citation purposes)the possibility of forearm rotation and...
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báo cáo hóa học: " Work-related musculoskeletal disorders in the automotive industry due to repetitive work implications for rehabilitation" docx
... examination of affected joint and other selected jo ints consisted of range of mot ion tests and resisted motion maneuvers (table 1). Range of motiondata were recorded as described by Rompe and Erlenkäm-per ... adduction of the fingers (with resistance)Extension and adduction of the thumb (with resistance)Cervical SpineRotation in normal position (neutral)Rotation in ante-/retroflexionSide-flexionExtension/FlexionNeck-compression/neck-tractionShoulderElevation ... work - implications for rehabilitation. Journal of Occupational Medicine and Toxicology 2010 5:6.Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online...
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báo cáo hóa học:"The cost and impact of male circumcision on HIV/AIDS in Botswana" potx
... cost of ART is based on a unit cost of P3599 in2010 and P4135 in 2015 for first-line antiretrovirals(ARVs) with an additional $133 for second-line ARVs[18].In addition, we assume continuation ... reduce the number of new HIVinfections in men, the number of new HIV infections inNumber of male circumcisions performed by scenarioFigure 1Number of male circumcisions performed by sce-nario.New ... development and planning for scaling up services to provide male cir-cumcision. It allows analysts and decision makers tounderstand the costs and impacts of policy options, and isa part of a larger...
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Báo cáo hóa học: " Research Article Multiple Solutions of p-Laplacian with Neumann and Robin Boundary Conditions for Both Resonance and Oscillation Problem" pdf
... C. Li, “The existence of infinitely many solutions of a class of nonlinear elliptic equations withNeumann boundary condition for both resonance and oscillation problems,” Nonlinear Analysis:Theory, ... ArticleMultiple Solutions of p-Laplacian withNeumann and Robin Boundary Conditions for Both Resonance and Oscillation ProblemJing Zhang and Xiaoping XueDepartment of Mathematics, Harbin Institute of Technology, ... points of J.Now, we construct the sub-sup solutions of p2. It is easy to see that M1is a constantsup-solution of p2 and −M2is a constant subsolution. Moreover, we consider εϕ1for...
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Báo cáo hóa học: " Research Article Neural Mechanisms of Motion Detection, Integration, and Segregation: From Biology to Artificial Image Processing Systems" docx
... solution of the aperture problem, a hysteresis effectin the temporal update of the motion representation givencontradicting evidence for motion direction, and the motioninterpretation for configurations ... feedbackconnections, the RF field size ratio between V1 and MT, and, as a prediction of our model, the spatial extension of the region of ambiguous motion. The time course of MTcell populations was ... based on the populationlevel of neuronal activity and gradual activation dynamics.Section 3 is built upon the general modelling framework and describes the neural model of motion estimation....
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