báo cáo hóa học:" Genetic lesions within the 3a gene of SARS-CoV" pdf

... that these two transmembrane domains are essential for the expression of 3a on the cell surface. It is possible that the aberrant nature of the oligo(T) tract in the 3a gene is akin to that of the ... smaller 3a gene products. We have shown that at least one of these truncated forms of 3a, named as 3amut1, can be detected in the lysate of infected cells [6...

Ngày tải lên: 20/06/2014, 04:20

... BioMed Central Page 1 of 4 (page number not for citation purposes) Virology Journal Open Access Short report Genetic lesions within the 3a gene of SARS-CoV Timothy HP Tan* 1 , Timothy ... properties) of 3a may be involved in modulating the trafficking properties of the spike protein [14]. Our results showed that the viruses in some of the patients appear to enc...

Ngày tải lên: 19/06/2014, 08:20

... representative of the diversity of P1 with a diver- gence up to 17.8% were selected. These isolates are repre- sentative of the diversity of the other parts of the genome as phylogenetic reconstruction ... purposes) Taken together our results at the virion scale demonstrate that the accumulation and genetic diversity of the P1 sup- pressor protein were not correlat...

Ngày tải lên: 20/06/2014, 01:20

... SSAT. The apparent synergism between the polymorphism of the ODC gene and the use of aspirin was proposed to be a combined result of an inhibition of polyamine biosynthesis and an activation of their ... biosynthesis, as DFMO retards the growth of the pancreas [101], but does not inhibit the secretory function of the exocrine part of the organ [102]. The...

Ngày tải lên: 30/03/2014, 13:20

... cell cross-priming through the expression of HLA/peptide complexes [6]. Based on these and following observations about the role of exosomes in antigen presentation, the exacerbated production of these vesicles ... Finally in 1996 these micropar- ticles were recognized for their central role in antigen pres- entation with the work of Graça Raposo and Hans Geuze of Utrecht Un...

Ngày tải lên: 18/06/2014, 15:20

... pathological fracture in the course of the disease. Plain radiograph of the left shoulder at the first presentationFigure 1 Plain radiograph of the left shoulder at the first pres- entation. The radiograph ... registrar who attributed the pain, swelling and the fracture of the clavicle to the mechanism of injury and advised follow-up in one month's time....

Ngày tải lên: 20/06/2014, 01:20

... poliovirus be considered, whether these be in the form of the development of new vaccines and/or anti-viral drugs. In this endeavor it is important that aspects of the pathogenesis of this virus, such ... of the questions currently under investigation in the Wimmer laboratory. The biochemical synthesis of poliovirus Despite the undeniable success of the Global Po...

Ngày tải lên: 20/06/2014, 01:20

... reported that the accumulation of point mutations in VP4 and VP7 genes of rotavirus strains was the main cause of the failure of the G or P-typing. Failures in the correct genotyping of G1, G2, ... typed if the Das's RT-PCR strategy were used. This analysis shows that the failure on the detection of the G1 strains could be due to the diversification of r...

Ngày tải lên: 20/06/2014, 01:20

... virologySARS-CoVVaccines Abstract In the aftermath of the SARS epidemic, there has been significant progress in understanding the molecular and cell biology of SARS-CoV. Some of the milestones are the availability of viral ... advances made in the identification and characterization of SARS-CoV genomes as well as describing the etiology of the virus and clinical fe...

Ngày tải lên: 20/06/2014, 04:20

... Fringe 2 NGO office 7200 rent or office repairs Other 3 NGO other office costs/supplies 7100 bank charges Other 3 NGO other office costs/supplies 7300 communications Other 3 NGO other office costs/supplies ... categories The purpose of Step 2 is to reorganize the information contained in the financial report into logical groups of expenses for key categories of “inputs” used...

Ngày tải lên: 20/06/2014, 08:20