... expressed both by melanocytes and melanoma cells. Among the melanoma-associated Ags identified so far, Melan -A has received particular attention because of its immune dom- inance in HLA -A2 + patients. A large ... clearer. Conclusion The finding of a conserved amino acid motif in the CDR3, together with the selective use of certain TRBJ and TRBV segments, indicates...
Ngày tải lên: 18/06/2014, 15:20
... effector to target cell ratio of 10:1, 30:1, 50:1 and 100:1. The cells were pelleted and after a 5 hour incubation period the supernatant was ana- lyzed in a gamma counter. Spontaneous and total ... with the candi- date pentadecapeptides. The in vitro sensitized cells were tested for cytotoxicity against HLA-matched HCMV- infected targets. The cytotoxicity assay was...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Identification of a biomarker panel using a multiplex proximity ligation assay improves accuracy of pancreatic cancer diagnosis" doc
... independently testing the validity of the model. At no time during our analysis of the data was there any overlap in training and test sets for any of the 10 independent test runs, nor was there any overlap in ... diagnostic accuracy compared to CA19-9 alone, our study was limited to patients with locally advanced pan- creatic cancer. Although extrapolation of these da...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học: " Identification of symptom domains in ulcerative colitis that occur frequently during flares and are responsive to changes in disease activity" ppt
... 5 Visual analogue scale ratings of symptoms that are absent during remission. A box plot of the VAS ratings of symp- toms that are absent during remission. All of the symptoms evaluated had VAS ratings ... found Visual analogue scale ratings of symptoms present during a flareFigure 3 Visual analogue scale ratings of symptoms present during a flare. A box plot of the...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học:" PAR1 is selectively over expressed in high grade breast cancer patients: a cohort study" docx
... of the data. EPA has been involved in PAR1 detection (WB, IF and IHC), and has been participated actively in the analysis and interpretation of the data. TAV has been involved in the analysis of ... only trace amounts of PAR1 and low levels of PAR2 and PAR4. These data are consistent with findings showing that high levels of PAR1 mRNA are found in infiltrating duct...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: "Retention of progenitor cell phenotype in otospheres from guinea pig and mouse cochlea" ppt
... potential to form spheres in the organ of Corti of 21-day-old mice, corresponding to nine days after the maturation of the auditory pathway [13]. As P3 guinea pigs should have had auditory maturation ... functional analysis of precursor, support and hair cells. Arq Int Otorrinolaringol 2007, 11:433-437. 16. Albuquerque AA, Rossato M, Oliveira JA, Hyppolito MA: Understandi...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: " Valuation of transfusion-free living in MDS: results of health utility interviews with patients" ppt
... validated by a hematologist. Face -to- face interviews used the feeling thermometer Visual Analogue Scale (VAS) and the Time Trade-Off (TTO) method to value the health states on a 0 (dead) to 1 (perfect ... all other aspects of health were nor- mal. They were then asked to place the health states at any point on the scale to correspond to their preferences for thes...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " Prevalence of multiple chronic conditions in the United States'''' Medicare population" pot
... population. Conclusion The CCW data files have tremendous value for ongoing evaluation of disease management programs and initia- tives. The longitudinal data and beneficiary linkage within the CCW are features of ... conducted using a Medicare FFS popula- tion. Administrative data were used to infer disease status. FFS claims were analyzed to determine whether there was an in...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " Estimation of minimally important differences in EQ-5D utility and VAS scores in cancer" pot
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: "Estimation of minimally important differences in EQ-5D utility and VAS scores in cancer" pot
... distribu- tion-based or anchor-based [6]. Anchor-based approaches compare changes seen in an individual's HRQL to an external criterion, such as a clinical measure or using a patient rated global change ... close to 6 in previous studies: 6–7 in hepatobiliary carcinoma [13], and 5–6 in breast cancer [10]. Final results were summarized as a range of MID esti- mates and...
Ngày tải lên: 18/06/2014, 22:20