báo cáo hóa học:" Effect of oligonucleotide primers in determining viral variability within hosts" ppt

... at determining natural diversity in microbial communities [1] or at identifying members of multigene families [2] and it is of special rel- evance for studies of viral variability within hosts, ... 2, respectively) was amplified in six infected patients. In the other two patients, part of the NS5A region including the ISDR (interferon-sensitivity determining region) an...

Ngày tải lên: 20/06/2014, 04:20

... in describing viral genetic variability at the intrapatient level has not been fully assessed yet. Results: To investigate the role of oligonucleotide design in estimating viral variability within ... primer set in both regions. BioMed Central Page 1 of 8 (page number not for citation purposes) Virology Journal Open Access Methodology Effect of oligonucleotide pri...

Ngày tải lên: 18/06/2014, 22:20

... her clinical status deteriorated, with progressive development of quadriparesis, ataxia, fatigue and cogni- tive decline. In 1994, a trial of interferon β-1b was discon- tinued because of increased ... activation, reduce expression and production of inflammatory molecules including interleukin-1β, tumor necrosis factor-α and inducible nitric oxide synthase, increase astrocyte metab-...

Ngày tải lên: 19/06/2014, 22:20

... 24% in an experiment initiated in winter 2010, but there was no observed effect in a similar experiment initiated in winter 2011. Similarly, the impact of NM-105 was less pronounced in the winter ... lower than the variation in the number of offspring during the year, indicating that the fluctuation in the absolute number of juveniles cannot be explained by biologica...

Ngày tải lên: 21/06/2014, 17:20

... 24% in an experiment initiated in winter 2010, but there was no observed effect in a similar experiment initiated in winter 2011. Similarly, the impact of NM-105 was less pronounced in the winter ... lower than the variation in the number of offspring during the year, indicating that the fluctuation in the absolute number of juveniles cannot be explained by biologica...

Ngày tải lên: 21/06/2014, 19:20

... since a single exacer- bation has a sustained effect on health status [7]. Inhaled corticosteroids (ICS) reduced the frequency of acute exac- erbations and also reduced the rate of decline in ... 15 and 60 minutes after the inhalation of bronchodilators (80 μg of ipratropium bromide plus 400 μg of salbuta- mol), using a metered-dose inhaler with a spacer device (InspirEase ® ; S...

Ngày tải lên: 18/06/2014, 19:20

... during the first, most intensive, year of treatment. The decline in QoL for certain items during the second, less intensive year of treatment, might be related to an increasing cumulative dose of ... importance of continuing close monitoring and counselling of both child and family during the whole of treatment. In HR children, reported scores on cognitive functioning were con...

Ngày tải lên: 18/06/2014, 19:20

... contact, the pointing was considered as unsuccessful. To determine pointing accu- racy, the ratio of unsuccessful pointings (without target contact) to the total number of pointings was calculated for ... Surprisingly, the effect of the difficulty of the task (and hence of the target size) on the temporal gaze-hand coordination has not been directly investi- gated. It is certainly...

Ngày tải lên: 19/06/2014, 08:20

... simple distractors from the training environment during robot-assisted movement training of people with stroke. Failure to control for distracting influences may at a minimum increase variability of results, and ... reduction in patient effort may dimin- ish training effectiveness. Developing a better understanding of the brain mechanisms that control the slacking response is impor-...

Ngày tải lên: 19/06/2014, 08:20

... alterations in movement patterns following stroke, including: decreased velocity, alterations in the shape of the velocity curve, loss of smoothness and loss of inter-joint coordination [2,3]. These ... study we were also interested in investigating whether the effects of auditory feedback differed depend- ing on side of stroke lesion. In stroke patients, reaching for target...

Ngày tải lên: 19/06/2014, 08:20