báo cáo hóa học:" Regulation of FeLV-945 by c-Myb binding and CBP recruitment to the LTR" doc

... conservation in the FeLV-945 LTR. c-Myb binding and CBP recruitment to the LTR positively regulated virus production, and thus may be responsible for the replicative advantage conferred by the 21-bp ... analysis of FeLV-945 replication indicated a regulatory role for c-Myb binding and recruitment of CBP to the 21-bp triplication. K-562 cells were...

Ngày tải lên: 20/06/2014, 04:20

... recruitment to the FeLV-945 LTR might interfere with CBP availability and thereby alter the regu- lation of CBP- responsive genes. Such alteration might then contribute to altered hematopoiesis and consequent hematologic ... in the presence of BioMed Central Page 1 of 10 (page number not for citation purposes) Virology Journal Open Access Research Regulation of...

Ngày tải lên: 18/06/2014, 22:20

... rehabil- itation. The long experience of these nurses leads both to a higher exposure to violence, and therefore to higher rates of post traumatic problems, and to a "natural brief- ing" of the staff, ... in the central and northern parts of Norway with about 1.1 million inhabitants. The unit consists of 4 wards with a total number of 21 beds. One...

Ngày tải lên: 18/06/2014, 18:20

... are needed to obtain the solution of the optimiza- tion problem. In order to limit the number of iterations the MNI has to be defined. The larger the value of the MNI, the more accurate the solution ... entropy The IE is an indicator of the image focus as well as the IC. In this case the smaller the entropy, the better the image focus [6]. In Table...

Ngày tải lên: 22/06/2014, 23:20

... budding, and Tsg101 appears to facili- tate this budding by linking the p6 late domain to the Vps pathway [22,23]. The PPXY motif has been shown to be the core sequence involved in binding to the ... [12]. To examine the involvement of Vps4A and Vps4B in the egress of HTLV-1 Gag-induced VLP, we analyzed the effects of overexpres- sion of DN mutants o...

Ngày tải lên: 20/06/2014, 01:20

... cleavage seen in our experiments. The observed translocation of ADAM9 and ADAM10 to the cyto- plasmic membrane further supports the idea of APP cleavage at the membrane by these secretases. Our experiments ... (Figs S5 and S6A) and protein levels of BACE1 (Figs S5 and S6C) were accompanied by its impaired trafficking and late translocation to the cellular memb...

Ngày tải lên: 16/03/2014, 01:20

... attempted to identify the apoptotic fac- tor(s) that were regulated by DNp63a in response to TNF-a. TNF-a is known to trigger apoptosis by diverse mechanisms, including caspase activation and the mitochondrial ... TAp63 ⁄ TAp73, and the silencing of DNp63a allows for the induction of the proapoptotic genes Bax, Noxa, and Puma [33]. Therefore, we employed real tim...

Ngày tải lên: 16/03/2014, 06:20

... esta- blishment of spermatogenesis and development of the adult pattern of testicular function. Our data indicated that the regulation of HSPG mRNA expression is HSPG-specific and depends on the Sertoli ... stimulated them by +35 and +55%, respectively (Tables 2 and 3). DISCUSSION This report shows, for the first time, the FSH regulation of HSPG mRNA expression...

Ngày tải lên: 17/03/2014, 23:20

... authors read and approved the final version of the manuscript. Disclaimer The findings and views in this report are those of the authors and do not necessarily reflect the views of the funding ... pain-relievers by persons with CFS compared to those in the ISF and the Well groups is not surprising because joint and muscle aches belong to the symptom com...

Ngày tải lên: 18/06/2014, 19:20