báo cáo hóa học:" Characterization and targeting of phosphatidylinositol-3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in renal cell cancer" pot

... Elfiky et al.: Characterization and targeting of phosphatidylinositol-3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in renal cell cancer. Journal of Translational Medicine 2011 9:133. Submit ... Medicine 2011, 9:133 http://www.translational-medicine.com/content/9/1/133 Page 5 of 10 RESEARCH Open Access Characterization and targeting of...

Ngày tải lên: 20/06/2014, 04:20

... Elfiky et al.: Characterization and targeting of phosphatidylinositol-3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in renal cell cancer. Journal of Translational Medicine 2011 9:133. Submit ... of 10 RESEARCH Open Access Characterization and targeting of phosphatidylinositol-3 kinase (PI3K) and mammalian target of ra...

Ngày tải lên: 18/06/2014, 22:20

... gel, followed by stain- ing with Coomassie R-250 and de-staining until protein bands could be easily visualized. Protein bands of interest were excised in as small of piece of gel as possible. ... For infection of WR, BSC-40 cells were maintained in infection media (EMEM) supple- mented with 5% FCS, 2 mM glutamine, and 10 mM gen- tamicin sulfate and were infected at a multip...

Ngày tải lên: 20/06/2014, 01:20

... viruses. The LT 50 s determined for SpliNPV and AcMNPV using LC 50 of the virus against 2 nd instar larvae were 4.2 and 5.8 days, respectively. A DNA segment of 405 bp containing highly conserved ... screening insects or /and other arthro- pods, especially crustacean species, crabs and shrimps for baculovirus infections and may be important in control- ling (preventing/enhanci...

Ngày tải lên: 20/06/2014, 01:20

... mean of two independent experiments. Note that the binding of 618F, 653F and VK-8 to these three cell lines is comparable. Binding of murine Muc16 to the lectin ConAFigure 5 Binding of murine ... expression of intracellular Muc16 was detected by using the 618F antibody (grey line). Dark line shows iso- type control. (C) Expression of cell surface and intracellular Muc16...

Ngày tải lên: 20/06/2014, 07:20

... of China (Grant number of 60576023 and 60636010), the State Key Program for Basic Research of China (2004CB619004), the State Key Program for Science and Technology of China (2009ZX02101-4) and ... starting materials of Al 2 O 3 and TiO 2 in a mole ratio of 1.5:1. The mixed powder in this ratio was ball-milled for 24 h, and then sintered at 1,500 °C for 7 h to form a...

Ngày tải lên: 22/06/2014, 00:20

... of its constituent elements being abundant in nature and not posing any health and environmental hazards. Therefore, SnS has a big potential to be used as solar absorber in a thin film solar cell ... diameter of 50 nm and a length up to several tens of micrometers. The synthesized SnS nanowires exhibit strong absorption in visible and near-infrared spectral region and t...

Ngày tải lên: 22/06/2014, 01:20

... ligand, is lysosomotrophic [15]. We and others have recently shown that selected sigma-2 ligands are capable of inducing apoptosis in a multitude of human and murine cancer cells lines and in ... apoptosis in all pancreas cancer cells in vitro. SV119 induced tumor apoptosis in both cycling cells at all phases (G1 to G2M/S) and in quiescent, G0, cells (Figure 3). Depend...

Ngày tải lên: 18/06/2014, 15:20

... SH-SY5Y cells from injury in the presence of neurotoxinsFigure 1 RPE-CM protect SH-SY5Y cells from injury in the presence of neurotoxins. (A) SH-SY5Y cells cultured without rotenone (Control), cells ... tissues and significantly improve AIR in 6-OHDA-lesioned rats To demonstrate the RPE cells survival in the host striatum, we performed HE staining and cytokeratin immunostain-...

Ngày tải lên: 18/06/2014, 15:20

... immune responses in humans. Further improvements of the recombinants, using the E6 and E7 transgenes deleted of the p53 and p105Rb cellular binding domain, might fur- ther increase the safety of the vaccine. ... difficulty of growing the virus in tissue cultures. VLP-based vaccines targeting the major L1 viral capsid protein of high- and low-risk HPV- types [44] proved e...

Ngày tải lên: 18/06/2014, 16:20