báo cáo hóa học:" Electroporation increases antitumoral efficacy of the bcl-2 antisense G3139 and chemotherapy in a human melanoma xenograft" ppt

... antisense oligodeoxynucleotides against bcl-2 (G3139) as well as the efficacy of combination chemotherapy in human melanoma xenografts. Methods: Melanoma- bearing nude mice were treated i.v. with G3139 and/ or cisplatin (DDP) ... mediated antisense potentiation. The objective of this study was to evaluate whether electroporation could increase the efficacy o...

Ngày tải lên: 20/06/2014, 04:20

... mediated antisense potentiation. The objective of this study was to evaluate whether electroporation could increase the efficacy of the bcl-2 ASO G3139 on mice bearing human melanoma in com- bination ... -GTGAACTGGGGGAGG ATTGT-3’ and reverse 5’-GGAGAAATCAAACAGAGGCC-3’ ; GAPDH forward 5’-CCAAGGTCATCCATGACAAC-3’ and reverse 5’ -TTACTCCTTGGAGGCCATGT-3’ . Reactions w...

Ngày tải lên: 18/06/2014, 22:20

... of onset was unclear in the remaining 89 cases. In addition, 79 cases (22 prelingual cases and 57 postlingual cases) had clear histories of administration of aminoglycoside, with an average age ... for deafness in the Chinese population. A prelim- inary investigation of the mutation spectrum and prevalence of GJB2 and SLC2 6A4 between typical areas from northern...

Ngày tải lên: 18/06/2014, 15:20

... capable of initiating immune responses against the melanoma. Thus the further development of this agent to be used as an immunogenic antigen in vaccine related therapies against melanoma is warranted. Abbreviations ALT: ... Tochigi, Japan), and Ms Setsuko Nakayama, Ms Asuka Asami and Ms Ruriko Miyake for their expert technical assistance (Department of Surgery and Bioengi...

Ngày tải lên: 18/06/2014, 16:20

... Miyashita M, Agdamag DM, Sasagawa T, Matsushita L, Salud LM, Salud CO, Saikawa K, Leano PS, Pagcaliwagan T, Acuna J, Ishizaki A, Kageyama S, Ichimura H: High-risk HPV types in lesions of the uterine ... prophylactic human papillomavirus L1 virus-like-particle vaccine on risk of cervical intraepithelial neoplasia grade 2, grade 3, and adenocarcinoma in situ: a combined analysi...

Ngày tải lên: 18/06/2014, 16:20

... VLG participated in linguistic validation process and interpretation of data. OF was responsible for the logistics and conduct of the study. All authors participated read and approved the final manuscript. Competing ... hypothesis of the area having a value of 0.5 in the population (and thus indicating the absence of inter-group discrimination) can be reje...

Ngày tải lên: 18/06/2014, 19:20

... recognizing the neural interaction of arm and hand and the importance of training using functionally complex movements, we asked the question whether training the arm and hand in an integr ated manner ... Piano trainer kinematic analyses. a. Daily averages during Virtual Piano training for finger fractionation defined as the difference between the angle of the MCP...

Ngày tải lên: 19/06/2014, 08:20

... showed increased capacity in the clearance of both A and α-synuclein without increasing microglial para- crine neurotoxicity strongly emphasizes the role of EP2 in neurodegeneration in both AD and ... sub- types of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol 1997, 122(2):217-224. 30. Tani K, Naganawa A, Ishida A, Egashira...

Ngày tải lên: 19/06/2014, 22:20

... LFPI-induced brain injury evoked an inflammatory reaction in the injured brain and attracted a population of activated microglia resulting in further damage of the brain. The fact that CCL20 expression ... Lunemann et. al. [25] have shown that following the formation of a brain lesion, microglia invade the damaged brain tissue after maturing and becoming activated...

Ngày tải lên: 19/06/2014, 22:20

... appeared tight it was z-lengthened rather than sacrificed. Cases of intrinsic contracture also had any intra-articular lesion addressed. Any implanted metal- work that was easily accessible and ... photograph showing the anterior capsule of the elbow through the lateral approachFigure 1 A clinical photograph showing the anterior capsule of the elbow through the lateral a...

Ngày tải lên: 20/06/2014, 01:20