báo cáo hóa học:" Cytotoxic T lymphocyte responses against melanocytes and melanoma" pptx

... by log steps to 10 -14 M. For each CTL clone, percent cytotoxicity was plotted against peptide concentration and the negative log of the concentration. The peptide concentration at which the curve ... by melanocytes. To uncouple vitiligo from melanoma destruction, it is important to understand if CTLs can respond against melanoma and melanocytes at different levels. Methods: To und...

Ngày tải lên: 20/06/2014, 04:20

... by log steps to 10 -14 M. For each CTL clone, percent cytotoxicity was plotted against peptide concentration and the negative log of the concentration. The peptide concentration at which the curve ... cytotoxicity (<20%) against melanoma or melanocytes, even though they had robust (95-100%) lysis against T2 pulsed with the relevant peptide. These data represent a modest but not s...

Ngày tải lên: 18/06/2014, 22:20

... method. Results Patient characteristics Patient characteristics are shown in Table 1 for the 22 patients treated with IFN-a 2b, the 22 patients not trea- ted with IFN-a 2b, and the 20 healthy subjects. O f the 22 ... with melanoma (22 patients treated in this study and the other 22 patients who were referred to our institution during the study); these data again suggest that Treg values a...

Ngày tải lên: 18/06/2014, 16:20

... of the NP and a compact structure. The zeta potential values alternating from negative to positive val- ues proved that the NP covering is efficient and, moreover, the final nanostructures obtained ... degradation ratio, m 0 is the original weight after equilibration time of swelling in PBS, and m t is the weight at time t. Cytotoxicity of nanostructures was determined by MTT cell prol...

Ngày tải lên: 22/06/2014, 01:20

... scale, together with the T- function. A threshold rule is then ap- plied. The method was tested with both real and simulated ECG signals. Results demonstrate a significantly better noise reduction ... improve the original two-dimensional phase-space portrait. Results on the MIT-BIH arrhythmia and long-term ST databases indicate excellent sensitivity and predictivity. The next two papers...

Ngày tải lên: 22/06/2014, 19:20

... other words, it is the duty of a UWB transmitter to detect a possi- ble victim device and cease tra nsmissions that might disturb such a device. Until 2010, the band between 4.1 and 4.8 GHz is exempt from ... shows that both radio systems are severely de- graded by interference from the other systems. It is also shown that the interference is asymmetric due to the het- erogeneity of the t...

Ngày tải lên: 22/06/2014, 22:20

... investigators who made the suc- cessful proposal to NSF to form the Institute for Pure and Applied Mathematics at UCLA, with a vision to promote collaborations be- tween the mathematical sciences with ... Professor at the Mathemat- ics Department, Hong Kong Baptist Univer- sity, and is an Honorary Professor in the De- partment of Mathematics, and an Adjunct Research Fellow in the E-Busi...

Ngày tải lên: 22/06/2014, 23:20

... Mami- Chouaib F: Cytotoxic T lymphocytes directed against a tumor-specific mutated antigen display similar HLA tetramer binding but distinct functional avidity and tissue distribution. Proc Natl Acad ... this public motif demonstrates that the dis- crepancy between the anti-viral and anti-melanoma Ag responses is only apparent and supports our hypothesis that the lack of common...

Ngày tải lên: 18/06/2014, 15:20

... http://www.translational-medicine.com/content/7/1/89 © 2009 Kmieciak et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0 ), ... determined in freshly isolated CD4+ T cells (day 0) and after a 3-day stimu- lation with anti-CD3/CD28 Abs (C). Freshly isolated a...

Ngày tải lên: 18/06/2014, 15:20

... Cells), PHA (Phytohemagglutinin), Tc (Cytotoxic T cell), Th1 (Type 1 T Helper cell), Th2 (Type 2 T Helper cell 2), THA (Total Hip Arthroplasty), TJA (Total Joint Arthroplasty), TNF- alpha (Tumor Necrosis ... that Th1 type reactivity may dominate lymphocyte reactivity responses to metals in patients with TJRs. This finding helps to identify the cellular pathways in metal-induced rea...

Ngày tải lên: 20/06/2014, 01:20