... phosphorylation of 14-3-3, a cytoplasmic anchor of Bax. Phosphorylation of 14-3-3 leads to dissociation of Bax from this protein and induces the mitochondrial dependent apoptotic pathwaythrough ... Sunayama J, Mori Y, Hattori S, Shimizu S, Tsujimoto Y, Yoshioka K,Masuyama N, Gotoh Y: JNK promotes Bax translocation to mitochondriathrough phosphorylation of 14-3-3 proteins. EMBO J 2004,23(8):1889-1899.49. ... proteins such as c-Abl. In response to DNAdamage, JNK induces phosphorylation of the 14-3-3 pro-tein and releases the binding of c-Abl from cytosol to thenucleus [49]. In the case of hematopoietic...