báo cáo hóa học:" SULFs in human neoplasia: implication as progression and prognosis factors" potx

... classes and predicts metastatic death. Cancer Res 2004, 64:7205-7209. doi:10.1186/1479-5876-9-72 Cite this article as: Bret et al.: SULFs in human neoplasia: implication as progression and prognosis ... SULF1 as an inhibitor of motility, invasion and angiogenesis and as a protein linked to drug-induced apoptosis. Hepatocyte growth factor (HGF)-mediated motility a...

Ngày tải lên: 18/06/2014, 19:20

... various aspects of motor and non-motor learning. Motor learning can be defined as modifications in motor performance with practice, as an increase in the repertoire of motor behaviour or as a new behaviour ... wrist-holding task has been demonstrated [108]. Once the task was learned, complex spike firing returned to baseline. According to Kitazawa and colleagues, complex spikes...

Ngày tải lên: 19/06/2014, 08:20

... that continuously changing the workload patterns was inter- esting. The overall results showed that an individualized exercise routine was ensured with the wearable unit in the Internet-based cycle ... Machine-Based Exercise Individualized exercise routines are effective for coping with gradual variations in the physical work capacity and for sustaining the motivation to exercise [1]....

Ngày tải lên: 19/06/2014, 10:20

... SEM) vinblastine (50) 3.2 ± 0.9 vinblastine (10) 1.1 ± 1.3 vinblastine (1) 0.9 ± 0.3 vinblastine(0.1) -0.6 ± 0.3 vincristine (50) 6.5 ± 2.1 vincristine (10) 3.3 ± 1.9 vincristine (1) 0.5 ± 0.6 vincristine ... with 3 H-thymi- dine for 4 h prior to harvesting and counting in a liquid scintillation counter. The drugs were used in the following concentrations: vinblastine and vincristi...

Ngày tải lên: 18/06/2014, 15:20

... Hematopoietic stem cells are being increasingly recognized as having diverse non-hematopoietic functions including produc- tion of angiogenic cytokines [48], and acting as an “innate” immune cell capable ... decrease s in circulating EPC, possibly as a result of chronic inflammatory mediators associated with these conditions [57,58]. In contrast, acute injury such as myocardial...

Ngày tải lên: 18/06/2014, 16:20

... In brief, human embryonic brain tissues were dissected into small blocks, incubated in phosphate-buffered saline (PBS) containing 0.25% trypsin and 40 µg/ml DNase and then dissociated into single ... entry of Ca 2+ was reduced to base- line values by SKF96365. Amplitude of Ca 2+ influx through SOC was measured as the difference between baseline and plateau levels and in fi...

Ngày tải lên: 19/06/2014, 22:20

... PD098059, the selective inhibitor of mitogen-activated protein kinase kinase 1 (MEK-1), was sufficient to abrogate COX-2 pro- moter activation, to increase COX-2 protein expression and to increase PGE 2 production ... kinase 1/2 (ERK1/2); Interleukin-1β (IL-1β); Mitogen-activated protein kinase (MAPK); Enzyme immunoabsorbent assay (EIA); Retinoic acid receptor (RAR); Retinoid X receptor (R...

Ngày tải lên: 19/06/2014, 22:20

... response, in patients undergoing vaccination with class I peptides only),, in vitro cytotoxicity against both peptides was markedly increased, when compared with baseline levels prior to vaccination. ... as shown in a previously published in vitro study [36]. In contrast, in our present in vivo study, both DCTs and DCTIs were comparable in inducing pep- tide-specific T cel...

Ngày tải lên: 18/06/2014, 15:20

... after TUNEL and Caspase-3 staining. Combination therapy with the sigma-2 ligand SV119 and the conventional chemotherapies gemcitabine and paclitaxel was evaluated in an allogenic animal model of pancreas ... that selected sigma-2 ligands are capable of inducing apoptosis in a multitude of human and murine cancer cells lines and in animal models of cancer including pancreas c...

Ngày tải lên: 18/06/2014, 15:20

... design, and was involved in drafting the manuscript. VT carried out the initial conception and design of the study, supervised and assisted in laboratory techniques, and was involved in drafting the ... supervision and was involved in drafting the manuscript. GM pro- vided samples, supervised in study design, and was involved in drafting the manuscript. TZ provided sam...

Ngày tải lên: 18/06/2014, 15:20