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báo cáo hóa học:" SULFs in human neoplasia: implication as progression and prognosis factors" potx

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Báo cáo sinh học: "SULFs in human neoplasia: implication as progression and prognosis factors" potx

... classes and predicts metastaticdeath. Cancer Res 2004, 64:7205-7209.doi:10.1186/1479-5876-9-72Cite this article as: Bret et al.: SULFs in human neoplasia: implication as progression and prognosis ... SULF1 as an inhibitor of motility, invasion and angiogenesis and as a protein linked to drug-induced apoptosis.Hepatocyte growth factor (HGF)-mediated motility and invasion were attenuated in SCCHN ... Open Access SULFs in human neoplasia: implication as progression and prognosis factorsCaroline Bret1,2,3, Jérôme Moreaux1, Jean-François Schved2,3, Dirk Hose4,5 and Bernard Klein1,3*AbstractBackground:...
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báo cáo hóa học: " Mechanisms of human cerebellar dysmetria: experimental evidence and current conceptual bases" potx

... various aspects of motor and non-motor learning. Motor learning can be defined as modifications in motor performance with practice, as anincrease in the repertoire of motor behaviour or as a newbehaviour ... wrist-holding task has beendemonstrated [108]. Once the task was learned, complexspike firing returned to baseline. According to Kitazawa and colleagues, complex spikes occurring early during areaching ... isdependent on the integrity of cerebellar networks.Findings in human are in good agreement with findings in animal studies [110]. Small lesions in the interpositusnucleus induce a permanent...
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báo cáo hóa học: "Personal customizing exercise with a wearable measurement and control unit" potx

... thatcontinuously changing the workload patterns was inter-esting. The overall results showed that an individualizedexercise routine was ensured with the wearable unit in theInternet-based cycle ... Machine-Based ExerciseIndividualized exercise routines are effective for copingwith gradual variations in the physical work capacity and for sustaining the motivation to exercise [1]. In machine-based ... with measurement and control functions is animportant step towards establishing a convenient and continuously supported wellnessenvironment.Introduction In rehabilitation engineering and health...
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báo cáo hóa học:" Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations" pdf

... SEM)vinblastine (50) 3.2 ± 0.9vinblastine (10) 1.1 ± 1.3vinblastine (1) 0.9 ± 0.3vinblastine(0.1) -0.6 ± 0.3vincristine (50) 6.5 ± 2.1vincristine (10) 3.3 ± 1.9vincristine (1) 0.5 ± 0.6vincristine ... with 3H-thymi-dine for 4 h prior to harvesting and counting in a liquid scintillation counter. The drugs were used in the following concentrations: vinblastine and vincristine, 1 nM; paclitaxel, ... vinblastine,the plasma concentrations measured were above the pre-clinically validated target concentration of 1 pM, as wasestimated based on the effect of vinblastine on angiogen-esis in...
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Báo cáo hóa học: " Nutraceutical augmentation of circulating endothelial progenitor cells and hematopoietic stem cells in human subjects" potx

... Hematopoieticstem cells are being increasingly recognized as havingdiverse non-hematopoietic functions including produc-tion of angiogenic cytokines [48], and acting as an“innate” immune cell capable ... decrease s in circulating EPC, possibly as a result of chronic inflammatory mediators associatedwith these conditions [57,58]. In contrast, acute injurysuch as myocardial infarction [59,60] and ... effectsreported. Supplementation was associated with a peakincrease of approximately 53% in the number of CD34expressing cells and and a 90% increase in CD133 cells in circulation. Furthermore,...
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báo cáo hóa học: " Platelet-activating factor enhancement of calcium influx and interleukin-6 expression, but not production, in human microglia" pptx

... In brief, human embryonicbrain tissues were dissected into small blocks, incubated in phosphate-buffered saline (PBS) containing 0.25%trypsin and 40 µg/ml DNase and then dissociated intosingle ... entry of Ca2+ was reduced to base-line values by SKF96365. Amplitude of Ca2+ influxthrough SOC was measured as the difference betweenbaseline and plateau levels and in five independent exper-iments ... has provided a detailed overview of ATP as an inducer of IL-6 expression and production in MG-5microglial cell line [12]. ATP and the purinergic agonistBzATP were both effective in increasing...
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báo cáo hóa học: " All-trans retinoic acid induces COX-2 and prostaglandin E2 synthesis in SH-SY5Y human neuroblastoma cells: involvement of retinoic acid receptors and extracellular-regulated kinase 1/2" potx

... PD098059,the selective inhibitor of mitogen-activated protein kinasekinase 1 (MEK-1), was sufficient to abrogate COX-2 pro-moter activation, to increase COX-2 protein expression and to increase PGE2 production ... kinase 1/2 (ERK1/2); Interleukin-1β(IL-1β); Mitogen-activated protein kinase (MAPK);Enzyme immunoabsorbent assay (EIA); Retinoic acidreceptor (RAR); Retinoid X receptor (RXR); MAP kinasekinase ... was followed by increased productionof PGE2. Basal release of PGE2 over 24 h was substantiallyincreased after incubation with 10 μM ATRA (Figure 1e).The increase in PGE2 production was...
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báo cáo hóa học:" Generation in vivo of peptide-specific cytotoxic T cells and presence of regulatory T cells during vaccination with hTERT (class I and II) peptide-pulsed DCs" pot

... response, in patients undergoing vaccination with class I peptidesonly),, in vitro cytotoxicity against both peptides wasmarkedly increased, when compared with baseline levelsprior to vaccination. ... as shown in a previously published in vitro study [36]. In contrast, in our present in vivo study,both DCTs and DCTIs were comparable in inducing pep-tide-specific T cell responses, following ... involving stage IV cutane-ous T cell lymphoma and Non-Hodgkin's lymphomapatients, has demonstrated intravenous denileukin difti-tox inducing disease regression (partial and complete in 20–30%...
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báo cáo hóa học:" Sigma-2 receptor ligands potentiate conventional chemotherapies and improve survival in models of pancreatic adenocarcinoma" ppt

... afterTUNEL and Caspase-3 staining. Combination therapy with the sigma-2 ligand SV119 and theconventional chemotherapies gemcitabine and paclitaxel was evaluated in an allogenic animal modelof pancreas ... that selected sigma-2ligands are capable of inducing apoptosis in a multitudeof human and murine cancer cells lines and in animalmodels of cancer including pancreas cancer [12,13,15].The ... adenocarcinoma cell lines compared to normal cell linesWe have previously reported that murine (Panc-02) and human (AsPC-1, CFPAC-1, and Panc-1) pancreatic aden-ocarcinoma cell lines display increased...
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báo cáo hóa học:" Alterations in vitamin D status and anti-microbial peptide levels in patients in the intensive care unit with sepsis" pot

... design, and was involved in draftingthe manuscript. VT carried out the initial conception and design of the study, supervised and assisted in laboratorytechniques, and was involved in drafting the ... supervision and was involved in drafting the manuscript. GM pro-vided samples, supervised in study design, and wasinvolved in drafting the manuscript. TZ provided samples,supervised in study design, and ... todecreased vitamin D binding protein synthesis, increasedclearance and/ or increased catabolism is unknown. Vita-min D may have an important role in regulation of theimmune system through induction...
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