báo cáo hóa học:" Inhibition of phosphorylated c-Met in rhabdomyosarcoma cell lines by a small molecule inhibitor SU11274" pdf

... of phosphorylated c-Met in rhabdomyosarcoma cell lines by a small molecule inhibitor SU11274. Journal of Translational Medicine 2011 9:64. Submit your next manuscript to BioMed Central and take ... Access Inhibition of phosphorylated c-Met in rhabdomyosarcoma cell lines by a small molecule inhibitor SU11274 Jinxuan Hou 1,2 , Jixin Dong 3 , L...

Ngày tải lên: 20/06/2014, 03:20

... Access Inhibition of phosphorylated c-Met in rhabdomyosarcoma cell lines by a small molecule inhibitor SU11274 Jinxuan Hou 1,2 , Jixin Dong 3 , Lijun Sun 4 , Liying Geng 3 , Jing Wang 3 , Jialin ... G, Rahman A, Chen G, Staten A, Griebel D, Pazdur R: Approval summary: imatinib mesylate in the treatment of metastatic and/or unresectable malignant gastrointestina...

Ngày tải lên: 18/06/2014, 19:20

... editorial assistance. This work was supported in part by the Canadian Institutes for Health Research Grant MOP-15017 and by a National Cancer Institute of Canada Terry Fox New Frontiers Grant. Jacques ... the various vectors, retroviral production and titer assays, transduc- tion and subsequent analysis of target cells, transcrip- tional assays, data acquisition and analysis, an...

Ngày tải lên: 20/06/2014, 01:20

... 8 and 22 h), and the HA production in the culture medium was quantitated by a sandwich binding protein assay using a very specific HABP (Fig. 3). By 8 h of culturing, a small amount of HA released into ... (Millipore Japan, Tokyo, Japan), and stained with anti-spHAS antibody according to the method of Towbin et al.[35]using3,3¢-diaminobenzidine tetrahydrochloride (Dojindo L...

Ngày tải lên: 08/03/2014, 09:20

... for ovarian cancer. The results showed high killing potential in ovarian cancer cell lines and a signifi- cant tumor growth inhibition in animals, indicating that the DTA-H19 construct has a high ... therapeutic potential and is a very promising candidate for ovarian cancer ther- apy in humans. Materials and methods Cell culture The human ovarian carcinoma cell lines (...

Ngày tải lên: 18/06/2014, 15:20

... urothelial cancers in the bladder are transitional cell carcinomas (TCC). Other important histologic types include squamous cell carcinoma and adenocarcinoma [1]. At presentation, tumors are usually ... inhibition a ctivity of H19-DTA-P4-DTA in human bladder carcinoma cell lines: Tumor growth inhibition activity of the H19-DTA, P4-DTA and H19-DTA-P4-DTA vectors in T24P...

Ngày tải lên: 18/06/2014, 16:20

... an increase in VF size of 5 – 7°. Reading training had a similar effect: In 34% of hemianopic patients who participated in read- ing training, an average VF enlargement of 5.4° was obtained after ... including an area of intact (dotted) and anopic (light shading) vision. The "treatment area" (dark shading) is a rectangular area in which LEDs are stimulated in...

Ngày tải lên: 19/06/2014, 10:20

... construction and analysis of rating scales. Background Patient-reported rating scales are gaining increasing importance in determining patient status and effective- ness of therapies. In such scales, ... collection, data analyses and inter- pretation, and drafting of the manuscript. HR participated in designing the study, data collection, data analyses and interpretation. JR parti...

Ngày tải lên: 20/06/2014, 16:20

... cathepsin B inhibition The cysteine protease inhibitory capacity in cell lysates was determined by measuring the inhibition of papain as well as cathepsin B. To measure the capacity of the cell lysate ... N39K–cystatin C, lacks inhibitory activity against the C13 family cyste- ine protease, legumain, because of removal of the key amino acid in the legumain-binding site...

Ngày tải lên: 16/03/2014, 06:20

... Kataoka K, Schubert P: Differential regulation of microglial activation by propentofylline via cAMP signaling. Brain Res 1998, 812:97-104. 51. Caggiano AO, Kraig RP: Prostaglandin E2 and 4-aminopyridine prevent ... activation of other kinases Inhibitory Effects of NE are mediated by β-ARs and replicated by cAMPFigure 4 Inhibitory Effects of NE are mediated by β-ARs and replica...

Ngày tải lên: 19/06/2014, 22:20