... patient sample. While the overall number of cells that stained positive for Aurora-A were higher in the carcinomas due to increased epithelial content, the inten- sity of the staining was equivalent ... Aurora-A staining of TMA core of benign ovarian tissue (20×). (G) Aurora-A staining of TMA core of ovar- ian carcinoma with adjuvant chemotherapy (20×). Journal of Tran...
Ngày tải lên: 18/06/2014, 15:20
... cells, while the intensity of staining was not considered. To determine the combined influence of LEF-1 and TCF4 on tumorigenesis, a LEF-1/TCF4 score was generated. Therefore, negative staining of LEF-1 ... rvival. These surprising findings suggest that TCF4 might be the main binding partner for b-catenin during development and progression of colorectal cancer whereas an enhance...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: " How does asthma influence the daily life of children? Results of focus group interviews" pot
... drawing about something they felt was related to their asthma. The moderator used the draw- ings for the facilitation of the discussion during the first session [18,19]. In the second session, the ... dis- cussed, the moderator started with the nominal group technique (NGT) in the third session [20]. Instead of the traditional voting procedure used in the NGT...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " Body mass index and health related quality of life in elementary school children: a pilot study" pdf
... where the inter- action of the physical, social, mental and emotional deter- minants of health are of interest. Health indices are useful in health policy and economic evaluation, because a sin- gle ... description of the survey is reported elsewhere [7]. In the spring of 2004, our investigation surveyed par- ents of children enrolled in an elementary school, kinde...
Ngày tải lên: 18/06/2014, 19:20
Báo cáo hóa học: " Innovative gait robot for the repetitive practice of floor walking and stair climbing up and down in stroke patients" pdf
... climbing up and down in line with the task- specific repetitive approach. However the inherent physi- cal effort of the therapists limit the intended intensity, a further burden is the risk of ... fixed to the back end of the linear guide. The for- ward and backward excursion of the principal sledge ensured the control of the step length. The mechanic desig...
Ngày tải lên: 19/06/2014, 08:20
báo cáo hóa học: " Simvastatin inhibits interferon-γ-induced MHC class II up-regulation in cultured astrocytes" potx
... assess- ing simvastatin in patients with relapsing remitting MS revealed a significant reduction in gadolinium-enhancing lesions on magnetic resonance imaging of the brain, which is indicative of ... test the effects of statins in MS are ongoing. Statins reduce the migration of leukocytes into the central nervous system (CNS), induce a Th2 phenotype in T-cells, and dec...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo hóa học: " Bioinformatic analysis suggests that the Orbivirus VP6 cistron encodes an overlapping gene" potx
... codons in each of the 48 sequences in each of the three forward reading frames. Note the conserved absence of stop codons in the +0 frame (i.e. the VP6 CDS) and in the +1 frame in the ORFX region. ... (ends) of the window. See [16] for further details of the MLOGD software. In (5)–(6) the null model, in each window, is that the sequence is non-c...
Ngày tải lên: 20/06/2014, 01:20
Báo cáo hóa học: " Viable chimaeric viruses confirm the biological importance of sequence specific maize streak virus movement protein and coat protein interactions" pdf
... were exchanged, no intra-ORF or intra-protein inter- actions were disrupted in the chimaeras. Determinants of chlorotic severity In view of the number of known – as well as the many likely but ... an isolate of the MSV-A strain, which is the predominant MSV strain infecting maize in Africa [25,26]. MSV-Set, on the other hand, is one of only two characterized repres...
Ngày tải lên: 20/06/2014, 01:20
Báo cáo hóa học: " Caveolin-1 interacts with the Gag precursor of murine leukaemia virus and modulates virus production" docx
... designed to investigate the biological significance of the Cav-1-Gag interaction. We reasoned that overexpression of fusion proteins con- taining the CBD of MA could block the interaction of Gag with ... co-localize predominantly in punctate patterns at the PM and to lower extent in perinuclear regions of the cell. Sequence comparisons uncovered a Cav-1 binding domai...
Ngày tải lên: 20/06/2014, 01:20
báo cáo hóa học:" A predicted protein, KIAA0247, is a cell cycle modulator in colorectal cancer cells under 5-FU treatment" doc
... G2/ M c heckpoint and in decreasing the number of cells in G2/M. At the same time, reduced levels of cyclins woul d negatively control the cell cycle checkpoints. The combination of cell cycle ... stages of CRC carcinogenesis [37]. There- fore, early during CRC carcinogenesis, an effect ive cyto- toxic effect induced by 5-FU in the KIAA0247- expressing cells could be c...
Ngày tải lên: 20/06/2014, 03:20