báo cáo hóa học:" Intravenous ascorbic acid to prevent and treat cancer-associated sepsis?" docx

... 9:25 http://www.translational-medicine.com/content/9/1/25 Page 11 of 13 REVIEW Open Access Intravenous ascorbic acid to prevent and treat cancer-associated sepsis? Thomas E Ichim 1,2 , Boris Minev 3 , Todd Braciak 2,4 , Brandon Luna 2 , Ron Hunninghake 1 , ... activation and cytochrome c release. To extend their study into the clinical realm, th e investigators pro- specti...

Ngày tải lên: 20/06/2014, 03:20

... activation and cytochrome c release. To extend their study into the clinical realm, th e investigators pro- spectively r andomized 34 patients wit h NYHA class III and IV heart failure to receive ... 23:99-109. 76. Edgington TS, Mackman N, Fan ST, Ruf W: Cellular immune and cytokine pathways resulting in tissue factor expression and relevance to septic shock. Nouv Rev Fr Hematol...

Ngày tải lên: 18/06/2014, 19:20

... happen to us." When we go to the doctor and get an injection, if it is not sterilized then we can get it. We go to the barber and if an old blade is used and if there is blood on it and if ... facilitators to moderate the focus group. In this study, the focus group facilitators consisted of the first and fourth authors, and a team of indigenous data collectors. Althou...

Ngày tải lên: 20/06/2014, 08:20

... between α and β and, moreover, we can say that for r ∈ 0, 1 it suffices to take n ∈ N such that n  1 −1/k <rto have |ft, x|≤2/3n  2 for all t, x between the graphs of α and β and r ≤ ... ,x 0,n  ,and −→ f f 1 ,f 2 , ,f n  : I × R n → R n . Our goal is to extend Theorem 5.3 to this multidimensional setting, which, as usual, requires the right hand side −→ f to...

Ngày tải lên: 21/06/2014, 20:20

... according to the variance expected in the study population and its responsiveness to therapy and/ or susceptibility to toxic side effects (i.e. the expected frequency of responders to a given treatment ... cells, PBMCs) ii. Samples to address the altering phenotypes of immune cells in relation to the natural history of disease and/ or treatment (i.e. pre, during, and post-tr...

Ngày tải lên: 18/06/2014, 15:20

... Awards will serve to encourage other investigators devoted to improving the "bench -to- bedside" and "bed- side -to- bench" concepts of translational medicine and respective initiatives. ... a sound basis to address unan- swered issues in this emerging basic and clinical research area in animal models and man toward delineating, e.g., the relative effects of...

Ngày tải lên: 18/06/2014, 15:20

... the cytokine bead array [25], and Meso-scale discovery sign arrays[26], and based on these platforms commercially available panels arenowavailabletoquantifycytokines/chemokines/ growth factors ... methodologies to couple antibodies t o elemental iso- topes combined with the use of inductively coupled plasma mass spectrometry (ICP-MS) to detect and quantify the antibodies in atomized...

Ngày tải lên: 18/06/2014, 16:20

... and Ab- 02 to cynomolgus monkey IL-21R are similar to the respective values for human IL-21R. To support preclini- cal development of Ab-01 and Ab-02, pharmacokinetic (PK) profiles of Ab-01 and ... conducted to monitor the PD activity of Ab-01 and Ab-02 in cyno- molgus monkeys following IV administration, and to cor- relate PD activity with serum concentrations of these an...

Ngày tải lên: 18/06/2014, 16:20

... congratulations to Hye-Won Chung [3] and to Raffaele Badolato and their respective co-workers, the 3rd “Excellence in Translational Medicine” and 2nd “Bedside -to- Bench” Awards are now history. We are hopeful ... are hopeful these Awards will serve to encourage other investigators devo ted to im proving the “bench -to- bedside” and “bedside -to- bench” concepts of transla- t...

Ngày tải lên: 18/06/2014, 16:20