... prepared using BOBSCRIPT [34]. Ó FEBS 2002 Two 1 : 1 binding modes for distamycin (Eur. J. Biochem. 269) 2875 Two 1 : 1 binding modes for distamycin in the minor groove of d(GGCCAATTGG) Koen Uytterhoeven 1 , ... current crystal structures describe the interaction of distamycin in the minor groove of the central CAATTG sequenc...
Ngày tải lên: 24/03/2014, 04:21
... Adenoviruses with an a v b integrin targeting moiety in the fiber shaft or the HI-loop increase tumor specificity without compromising antitumor efficacy in magnetic resonance imaging of colorectal ... death in any of the cell lines. Antitumor efficacy of RGD modified viruses in the spleen- to-liver colorectal cancer mode...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: " Inflammatory cytokine levels correlate with amyloid load in transgenic mouse models of Alzheimer''''s disease" potx
... administration of ibuprofen can reduce plaque pathology and brain Aβ levels in these animal models of AD [8,9]. There are numerous reports of increased levels of cytokines in the brains of Alzheimer's ... Acosta- Martinez JP, Ortiz GG: Kinetics of the neuroinflammation-oxi- Additional File 1 Correlation table of levels of different β -amyloid species with...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo hóa học: "Sweat rate and sodium loss during work in the heat" ppt
... collecting devices were removed and placed in individual sealed plastic bags. The subjects were then instructed to shower without wetting their hair, abstain from drinking, eating, or urinating, and ... ensure they were completely dry before re-dressing into the clothes in which they were originally weighed. After re- weighing, the sweat rate (mL. min -1 ) was calculated from...
Ngày tải lên: 20/06/2014, 00:20
báo cáo hóa học: " Musculoskeletal disorders early diagnosis: A retrospective study in the occupational medicine setting" docx
... 6:1 http://www.occup-med.com/content/6/1/1 Page 3 of 6 CAS E REP O R T Open Access Musculoskeletal disorders early diagnosis: A retrospective study in the occupational medicine setting John Kulin 1*† , MaryRose Reaston 2† Abstract Electrodiagnostic ... of Labor and Occupational Safety and Health Administration (OSHA) define a musculoske- letal disorder (MSD) as an in...
Ngày tải lên: 20/06/2014, 00:20
Báo cáo hóa học: " A novel adenovirus vector for easy cloning in the E3 region downstream of the CMV promoter" pot
... Journal Open Access Short report A novel adenovirus vector for easy cloning in the E3 region downstream of the CMV promoter Laurent Mailly 1,2 , Charlotte Boulade-Ladame 1 , Georges Orfanoudakis 1 ... shuttle plasmid containing a promoter for the expression of the transgene. After selection of recombinants, the plasmid DNA of each clone has to be...
Ngày tải lên: 20/06/2014, 01:20
Báo cáo hóa học: " Discovery of significant variants containing large deletions in the 5''''UTR of human hepatitis C virus (HCV)" pot
... 3 BioMed Central Page 1 of 5 (page number not for citation purposes) Virology Journal Open Access Research Discovery of significant variants containing large deletions in the 5'UTR of human hepatitis ... lacking 116 bp. Most of the IRES, including loops IIIa, IIIb, and IIIc, was missing (Figure 2). The consensus sequence of the 313 plasma HCV that con...
Ngày tải lên: 20/06/2014, 02:20
báo cáo hóa học:" HIV prevention is not enough: child survival in the context of prevention of mother to child HIV transmission" potx
... denominators matter In the absence of any interventions, about a third of infants born to HIV- infected mothers acquire HIV infec- tion. About 20% of infants born to HIV- infected mothers acquire HIV ... Society Open Access Commentary HIV prevention is not enough: child survival in the context of prevention of mother to child HIV transmis...
Ngày tải lên: 20/06/2014, 08:20
báo cáo hóa học:" An HIV epidemic is ready to emerge in the Philippines Review" ppt
... the spread, understanding key epidemic drivers and planning the control of HIV in the Philippines. There are currently four types of surveillance systems in place in the Philippines: 1. The HIV/ AIDS ... suggests that there may be an emerging HIV epidemic among Filipino MSM. The emergence of an increasing HIV epidemic in the Philippines is evident...
Ngày tải lên: 20/06/2014, 08:20
Báo cáo hóa học: "A new low-complexity angular spread estimator in the presence of line-of-sight with angular distribution selection" pptx
... as: Bousnina et al.: A new low-complexity angular spread estimator in the presence of line -of- sight with angular distribution selection. EURASIP Journal on Advances in Signal Processing 2011 ... distribution: R i,k ≈ 1 1+2π 2 σ 2 θ ik d 2 ik λ 2 cos 2 θ ik exp −j2π d ik λ sin θ ik . (7) In this study, we are inte rested in estimating the mean AoA and t...
Ngày tải lên: 20/06/2014, 22:20
Báo cáo hóa học: " Research Article A Hilbert-Type Integral Inequality in the Whole Plane with the Homogeneous Kernel of Degree −2 Dongmei Xin and Bicheng Yang" pdf
... real and complex analysis and estimating the weight functions, we build a new Hilbert-type integral inequality in the whole plane with the homogeneous kernel of degree −2 involving some parameters ... analysis, the main objective of this paper is to give a new Hilbert-type integral inequality in the whole plane with the homogeneou...
Ngày tải lên: 21/06/2014, 05:20
Báo cáo hóa học: " Research Article Edge Adaptive Color Demosaicking Based on the Spatial Correlation of the Bayer Color Difference" pptx
... 5. 2. Spatial Correlation on theBayerColorDifferencePlane In the proposed method, the region type and the edge direction are determined directly on the Bayer CFA samples based on the correlation of ... (Non). Therefore, the final types of the edge direction are EDT ={Hor, Ver, Non}. In the proposed edge direction estimation, the diagonal directional...
Ngày tải lên: 21/06/2014, 08:20
Báo cáo hóa học: " Research Article Online Speech/Music Segmentation Based on the Variance Mean of Filter Bank Energy" pdf
... novel feature for online speech/music segmentation based on the variance mean of filter bank energy (VMFBE). The idea that encouraged the feature’s construction is energy variation in a narrow frequency ... Corporation EURASIP Journal on Advances in Signal Processing Volume 2009, Article ID 628570, 13 pages doi:10.1155/2009/628570 Research Article Online Spee...
Ngày tải lên: 21/06/2014, 19:20
Báo cáo hóa học: " Research Article Asymptotic Bounds for Frequency Estimation in the Presence of Multiplicative Noise" doc
... j. (32) The form in (31) is useful to calculate the exact CRB in the presence of AR colored noise. Substituting (31) into (3), and performing the matrix expansion, the FIM entries in the presence of ... small. The effect is more prominent with the increase in the data length. In the following, we will regu- larize this infor mation singularity using the...
Ngày tải lên: 22/06/2014, 23:20
Báo cáo y học: "Functional constraint and small insertions and deletions in the ENCODE regions of the human genome" ppsx
... discrete regions that encompass 30 mega- bases, or about 1% of the human genome, with 14 of these regions (about 15 megabases) selected manually and the remainder randomly [11]. Small indels in the ENCODE regions ... in the human genome. A minority of insertions and deletions may also have plausibly played a major role in spe- ciation events, includin...
Ngày tải lên: 14/08/2014, 08:20