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Báo cáo hóa học: " Discovery of significant variants containing large deletions in the 5''''''''UTR of human hepatitis C virus (HCV)" pot

Báo cáo Y học: Two 1 : 1 binding modes for distamycin in the minor groove of d(GGCCAATTGG) docx

Báo cáo Y học: Two 1 : 1 binding modes for distamycin in the minor groove of d(GGCCAATTGG) docx

... prepared usingBOBSCRIPT[34].Ó FEBS 2002 Two 1 : 1 binding modes for distamycin (Eur. J. Biochem. 269) 2875 Two 1 : 1 binding modes for distamycin in the minor groove of d(GGCCAATTGG) Koen Uytterhoeven 1 , ... current crystal structures describe the interaction of distamycin in the minor groove of the central CAATTGsequence in a 1 : 1 binding mode. The present tight crystalpacking due to the triplet formation ... side-by-side binding of two distamycin molecules in the minor groove of d(CGCAATTGCG) [6]. More structuralinformation about this 2 : 1 binding mode was firstprovided by the crystal structure of...
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Báo cáo hóa học: " Adenoviruses with an avb integrin targeting moiety in the fiber shaft or the HI-loop increase tumor specificity without compromising antitumor efficacy in magnetic resonance imaging of colorectal cancer metastases" pdf

... Adenoviruses with an avb integrin targeting moiety in the fiber shaft or the HI-loop increase tumor specificity without compromising antitumor efficacy in magnetic resonance imaging of colorectal ... death in any of the cell lines. Antitumor efficacy of RGD modified viruses in the spleen-to-liver colorectal cancer modelColo rectal cancer cells (HCT116) were injected into the splee n of NMRI ... RGDmodification in the capsidSince avb integrin targeted vectors showed an increasedtransduction efficacy in colorectal cancer cells in vitro, the biodistribution of RGD modified viruses in vivo wastested...
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báo cáo hóa học: " Inflammatory cytokine levels correlate with amyloid load in transgenic mouse models of Alzheimer''''s disease" potx

... administration of ibuprofen can reduceplaque pathology and brain Aβ levels in these animal models of AD [8,9].There are numerous reports of increased levels of cytokines in the brains of Alzheimer's ... Acosta-Martinez JP, Ortiz GG: Kinetics of the neuroinflammation-oxi-Additional File 1Correlation table of levels of different β -amyloid species with cytokines in transgenic mouse models of Alzheimer's ... were Cytokine production by brain slices from transgenic mouse models of AD at 15 months of ageFigure 1 Cytokine production by brain slices from transgenic mouse models of AD at 15 months of age....
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Báo cáo hóa học: "Sweat rate and sodium loss during work in the heat" ppt

... collecting devices were removed and placed in individual sealed plastic bags. The subjects werethen instructed to shower without wetting their hair,abstain from drinking, eating, or urinating, and ... ensurethey were completely dry before re-dressing into the clothes in which they were originally weighed. After re-weighing, the sweat rate (mL. min-1) was calculated from the weight loss of the ... greater sweat rate (water loss) in summer than in winter as shown in Fig 2. The mean water loss in the summer was 7.8 mL.min-1(0.47 L.h-1) compared with 6.9 mL.min-1 (0.41 L.h-1) in winter (Table...
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báo cáo hóa học: " Musculoskeletal disorders early diagnosis: A retrospective study in the occupational medicine setting" docx

... 6:1http://www.occup-med.com/content/6/1/1Page 3 of 6CAS E REP O R T Open Access Musculoskeletal disorders early diagnosis: A retrospective study in the occupational medicine settingJohn Kulin1*†, MaryRose Reaston2†AbstractElectrodiagnostic ... of Labor and Occupational Safetyand Health Administration (OSHA) define a musculoske-letal disorder (MSD) as an injury of the muscles, nerves,tendons, ligaments, joints, cartilage and spinal ... sensorsplaced on the skin surface while simultaneously assessing functional capacity at rest and during full range ofmotion. The evaluation is non-invasive and non-loading and provides measurements in...
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Báo cáo hóa học: " A novel adenovirus vector for easy cloning in the E3 region downstream of the CMV promoter" pot

... JournalOpen AccessShort report A novel adenovirus vector for easy cloning in the E3 region downstream of the CMV promoterLaurent Mailly1,2, Charlotte Boulade-Ladame1, Georges Orfanoudakis1 ... shuttle plasmid containing a promoter for the expression of the transgene. After selection of recombinants, the plasmid DNA of each clone has to betransferred into an other bacterial strain (i.e. ... recombinant adenoviral vectors. HumGene Ther 1999, 10(12):2013-2017.7. Mizuguchi H, Kay MA, Hayakawa T: In vitro ligation-based cloning of foreign DNAs into the E3 and E1 deletion regions for...
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Báo cáo hóa học:

Báo cáo hóa học: " Discovery of significant variants containing large deletions in the 5''''UTR of human hepatitis C virus (HCV)" pot

... 3BioMed CentralPage 1 of 5(page number not for citation purposes)Virology JournalOpen AccessResearch Discovery of significant variants containing large deletions in the 5'UTR of human hepatitis ... lacking 116 bp. Most of the IRES,including loops IIIa, IIIb, and IIIc, was missing (Figure 2). The consensus sequence of the 313 plasma HCV that con-tained the deletions was the same as the consensussequence ... patient 313 contains the extra C, which could cause the HCV RNA polymerase to accidentally create the deleted versions of the 5'UTR. However, of our isolates containing the extra C& apos;s,...
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báo cáo hóa học:" HIV prevention is not enough: child survival in the context of prevention of mother to child HIV transmission" potx

... denominators matter In the absence of any interventions, about a third of infants born to HIV- infected mothers acquire HIV infec-tion. About 20% of infants born to HIV- infected mothersacquire HIV ... SocietyOpen AccessCommentary HIV prevention is not enough: child survival in the context of prevention of mother to child HIV transmissionLouise Kuhn*1, Moses Sinkala2, DonMThea3, Chipepo Kankasa4 ... randomized to breastfeed. But abstinence from breastfeeding was able to reduce HIV transmission. Sadly, adding together thesecompeting risks, there is no net benefit in terms of HIV- free survival of...
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báo cáo hóa học:" An HIV epidemic is ready to emerge in the Philippines Review" ppt

... the spread, understanding key epidemic driversand planning the control of HIV in the Philippines. Thereare currently four types of surveillance systems in place in the Philippines: 1. The HIV/ AIDS ... suggests that there may be an emerging HIV epidemic among Filipino MSM. The emergence of an increasing HIV epidemic in the Philippines is evident from trends in monthly reportedFarr and Wilson ... groupstend to have greater sexual activity. The fact that the aver-age age is decreasing is a strong indicator that HIV inci-dence could increase substantially in the future in the Philippines. This...
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Báo cáo hóa học: "A new low-complexity angular spread estimator in the presence of line-of-sight with angular distribution selection" pptx

... as: Bousnina et al.: A new low-complexity angular spread estimator in the presence of line -of- sight with angular distribution selection. EURASIP Journal on Advances in Signal Processing2011 ... distribution: Ri,k≈11+2π2σ2θikd2ikλ2cos2θikexp−j2πdikλsin θik.(7) In this study, we are inte rested in estimating the mean AoA and the AS. In other terms, we determine the mean and the standard deviation of the angular ditribution of the ... 0.05.(31) The selected angular distribution, ˆγf, is the one asso-ciated with the minimum of the sum (24) (using the standard deviations of the AS estimates of di stant ele-ments). The final mean...
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Báo cáo hóa học: " Research Article A Hilbert-Type Integral Inequality in the Whole Plane with the Homogeneous Kernel of Degree −2 Dongmei Xin and Bicheng Yang" pdf

... real and complex analysis and estimating the weight functions, we build a new Hilbert-type integral inequality in the whole plane with the homogeneous kernel of degree −2 involving some parameters ... analysis, the main objective of this paper is to give a new Hilbert-type integral inequality in the whole plane with the homogeneous kernel of degree −2 involving some parameters and a bestconstant factor. ... π∞−∞e−xf2xdx∞−∞e−xg2x1/2,1.2where the constant factor π is the best possible. Zeng and Xie 11 also give a new inequality in the whole plane. By applying the method of 10, 11 and using the way of real and complex analysis,the...
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Báo cáo hóa học: " Research Article Edge Adaptive Color Demosaicking Based on the Spatial Correlation of the Bayer Color Difference" pptx

... 5.2. Spatial Correlation on theBayerColorDifferencePlaneIn the proposed method, the region type and the edge direction are determined directly on the Bayer CFA samples based on the correlation of ... (Non). Therefore, the final types of the edge direction are EDT={Hor, Ver, Non}.In the proposed edge direction estimation, the diagonaldirectional edge is considered as the combination of the horizontal ... difference of the Bayer samplesprovides key to directly estimate the edge direction on the Bayer pattern. In the conventional SSC -based methods, the smoothness of the Bayer color difference along an edge...
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Báo cáo hóa học: " Research Article Online Speech/Music Segmentation Based on the Variance Mean of Filter Bank Energy" pdf

... novel feature for online speech/music segmentation based on the variance mean of filter bank energy(VMFBE). The idea that encouraged the feature’s construction is energy variation in a narrow frequency ... CorporationEURASIP Journal on Advances in Signal ProcessingVolume 2009, Article ID 628570, 13 pagesdoi:10.1155/2009/628570 Research Article Online Speech/Music Segmentation Based on the Variance Mean ... Framework The performance of the speech/music segmentation andclassification was evaluated on the databases, as described inSections 4.1 and 4.2.5.1. Basic Structure of the Speech/Music Segmentation...
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Báo cáo hóa học: " Research Article Asymptotic Bounds for Frequency Estimation in the Presence of Multiplicative Noise" doc

... j.(32) The form in (31) is useful to calculate the exact CRB in the presence of AR colored noise. Substituting (31) into (3),and performing the matrix expansion, the FIM entries in the presence of ... small. The effect is more prominent with the increase in the data length. In the following, we will regu-larize this infor mation singularity using the CMT. The basicidea of CMT is to multiply the ... maintaining regular conditions.4. BOUNDS FOR FREQUENCY ESTIMATION EVALUATED IN THE FREQUENCY DOMAIN The time domain CRB evaluation discussed in the previoussection requires matrix inversion. In...
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Báo cáo y học: "Functional constraint and small insertions and deletions in the ENCODE regions of the human genome" ppsx

... discrete regions that encompass 30 mega-bases, or about 1% of the human genome, with 14 of these regions (about 15 megabases) selected manually and the remainder randomly [11]. Small indels in the ENCODE regions ... in the human genome. A minority of insertions and deletions may also have plausibly played a major role in spe-ciation events, including human- chimpanzee phenotypic dif-ferences [9,10]. An investigation ... features and evolutionary constrained sequence?Here we describe the distribution of small indels (rangingfrom 1 to 20 base pairs [bp]) in the manually and randomlyselected ENCODE regions, their...
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