Báo cáo hóa học: " Members of the Hyposoter didymator Ichnovirus repeat element gene family are differentially expressed in Spodoptera frugiperda" docx

... segment containing the corresponding gene (except for Hd ichnovirus) then the rep gene number. Arrow- heads indicate beginning and ending of the conserved repeated element motif as defined by Theilmann ... rep11 lacks the C-terminal part of the repeated element motif, compared to the other rep proteins. Whole rep protein sequences of several Ichnoviruses con- tainin...

Ngày tải lên: 20/06/2014, 01:20

... only in one HSV-1 positive patient the examination of the fundus of the eye revealed posterior uveitis and inflammatory changes of retinal ves- sels (vasculitis). On the other hand VZV intraocular ... assay in Greece. The assay's ability to detect herpesviruses in a wide range of specimen types in a single amplification enhances its util- ity in the clinical...

Ngày tải lên: 20/06/2014, 01:20

... difficult to generate large numbers of high avidity tumor-reactive CD8 + T cells in individual patients in time and maintain their survival in vivo. The solution is gene therapy, by engineering T cells ... patients with melanoma in combination with high dose IL-2 has been shown to achieve clinical responses in the range of 50%. However, minimal activity of IL-2 in th...

Ngày tải lên: 18/06/2014, 15:20

... and ointment vehicle. Clinical rating was performed twice a week during the treatment phase assessing the Total Clinical Score (TCS). The Total Clinical Score is defined as the sum of erythema (0-3), ... positively stained epidermal area, i.e. the area of positive CK10 or CK16 in relation to the total epidermal area. These measurements were per- formed with the Visiopharm...

Ngày tải lên: 18/06/2014, 15:20

... in culture; HMK, participated in writing of the manuscript; DN, excised tumors and provided the material for research; RH, in charge of analyzing tumor specimens and participated in writing the ... between the V600E and V600K mutations. Our preclinical data demonstrating s imilar kinase activity of the V600K and V600E mutations, together with clear evidence of clinic...

Ngày tải lên: 18/06/2014, 16:20

... significant increase of NGF, BDNF and NT-3 transcripts and NGF proteins in both the NSC cultures and the CSF of the rats. The immunochemical staining for MHC in brain sections and the enzyme-linked immunosorbent ... staining. Immunohistochemistry staining Immunohistochemical staining of nestin and BrdU were performed to assess the property of NSC in cultures and trac...

Ngày tải lên: 18/06/2014, 16:20

... important role in the stabilization of mRNA by reversibly binding to conserved sequence elements, most often AU-rich elements (AREs), in the untranslated regions (UTRs) of the mRNA resulting in either ... implicated in cisplatin resistance, i.e. decreased drug uptake, insufficient DNA-binding of the drug, increased DNA-repair of cisplatin adducts and fail- ure of ind...

Ngày tải lên: 18/06/2014, 16:20

... mutation in the GJB2 gene with either rece ssive or unclear pathogenicity, despite direct sequencing of the entire coding region of the gene [12-14]. The ratio of a 309-kb deletion involving the GJB6 ... or other noncoding regions of GJB2. To evaluate the impact of the IVS1+1G>A splice-site mutation and the b asal promoter region in the noncod- ingpartof...

Ngày tải lên: 18/06/2014, 16:20

... RGDechiHCit in the selective inhibition of endothelial a V b 3 integrin in vitro and in vivo. Such inhibition opens new fields of investigation on the mechanisms of angiogenesis, offering clinical ... proteins containing the RGD triad, many studies have demonstrated that the aminoa cids flanking the RGD sequence of high-affinity ligands appear to be critical in modul...

Ngày tải lên: 18/06/2014, 16:20

... including the RDQ, GIS and the Gastrointestinal Symptoms Rating Scale, may be one such instrument, providing more accurate and sensitive quantification of the symptoms and the impact of these in patients ... within the specified identification period were included in the study population and irrespective of the number of times they visited that practitioner. Also, t...

Ngày tải lên: 18/06/2014, 18:20