... 8; CDH13, cadherin 13; CDKN1B, cyclin-dependent kinase inhibitor 1B; CDKN1C, cyclin-dependent kinase inhibitor 1C; CDKN2A, cyclin-dependent kinase inhibitor 2A; COL1A2, alpha 2 type I collagen; ... their amino terminus (N), including methylation and acetylation, which determine chromatin structure, resulting in the modulation of accessibility of DNA for the transcriptional machinery. The ... possess both de novo and maintenance functions in vivo, and that they cooperate in establishing and maintaining DNA methylation patterns[11-14]. The methylation of promoter regions inhibitsgene expression...