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Báo cáo hóa học: " Inhibition of histone deacetylation in 293GPG packaging cell line improves the production of self-inactivating MLV-derived retroviral vectors" pdf

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Báo cáo hóa học: " Increased matrix metalloproteinase activation in esophageal squamous cell carcinoma" doc

... Medicine 2010, 8:91http://www.translational-medicine.com/content/8/1/91Page 5 of 7RESEARC H Open Access Increased matrix metalloproteinase activation in esophageal squamous cell carcinomaSumana ... markers in the clinic.Background Esophageal cancer is the sixth leading cause of cancerdeath in the world [1]. Eighty percent of esophageal can-cer cases occur in developing countries, and in theseareas ... theseareas about 90% are esophageal squamous cell carcino-mas (ESCC) [2]. In high-risk areas, such as Linxian,China, ESCC is the leading cause of cancer death withmortality rates in excess of 100/100,000...
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Báo cáo hóa học: "Inhibiting adenoid cystic carcinoma cells growth and metastasis by blocking the expression of ADAM 10 using RNA interference" pdf

... ADAM 10 expression in SACC-LM cells To investigate whether ADAM 10 expression was essen-tial for the metastatic capability of SACC-LM cells, stable ADAM 10 RNAi transfected cells (SACC- ADAM1 0-RNAi) ... supportingtheroleofADAM10incellgrowthinSACC-LMcells(Figure 5 C). In addition, the affect of gene silencing of ADAM 10 on the cell migration ability of SACC-LM cells was also investigated by transwell ... designed using the software siRNA Target Designer (Promega, Madison,WI, USA). The preparation of the RNAi vector expres-sing the human ADAM 10 short hairpin RNA (shRNA)was performed using the pSuper...
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báo cáo hóa học: " Inhibition of microglial inflammatory responses by norepinephrine: effects on nitric oxide and interleukin-1β production" pdf

... 1 of 15(page number not for citation purposes)Journal of NeuroinflammationOpen AccessResearch Inhibition of microglial inflammatory responses by norepinephrine: effects on nitric oxide and ... effects of NE on IL-1β were observed at concen-trations lower than that needed for maximal inhibition of NOS2 expression, and resulted in greater extent of inhibi-tion (over 80% inhibition of IL-1β ... An under-standing of the contrasting effects of PKA and AC inhibi-tors on nitrite production and NOS2 expression maytherefore help to explain reported divergent effects of cAMP on microglial...
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báo cáo hóa học: " 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) attenuates the expression of LPS- and Aβ peptide-induced inflammatory mediators in astroglia" pptx

... LPS /Aβ- induced inflammatory processes by blocking the expression of proinflammatory cytokine, iNOS, COX-2 and MnSOD genes, and by inhibition of ROS generation and depletion of glutathione in astroglial ... AICARattenuation of LPS- or cytokine /Aβ- induced expression of inflammatory mediators (e.g. iNOS, COX-2 and cytokines) by inhibiting the activation of transcriptionfactors (NFκB and C/EBP) required for induction ... purposes)AICAR inhibits LPS- and Aβ- (25–35) induced expression of iNOS, COX-2, and MnSOD in astrocyte-enriched glial cellsFigure 4AICAR inhibits LPS- and Aβ- (25–35) induced expression of iNOS, COX-2, and...
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báo cáo hóa học: " Inhibition of NF-κB activation by 5-lipoxygenase inhibitors protects brain against injury in a rat model of focal cerebral ischemia" docx

... AccessResearch Inhibition of NF-κB activation by 5-lipoxygenase inhibitors protects brain against injury in a rat model of focal cerebral ischemiaManu Jatana1, Shailendra Giri1, Mubeen A Ansari1, Chinnasamy ... Gilg AG, Sekhon C, Singh I, SinghAK: Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke. J Neurosci ... injury in rats via down-regulation of theinflammatory mediators NF-κB and iNOS. Thus, inhibit-ing the 5-LOX /NF-κB pathway holds therapeutic potentialto attenuate inflammation-mediated brain...
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báo cáo hóa học: " Inhibition of secreted phospholipase A2 by neuron survival and anti-inflammatory peptide CHEC-9" docx

... purposes)Journal of NeuroinflammationOpen AccessResearch Inhibition of secreted phospholipase A2 by neuron survival and anti-inflammatory peptide CHEC-9Timothy J Cunningham*, Jaquie Maciejewski and Lihua ... elevation of sPLA2s are associ-ated with most forms of inflammation [1-5]. The secreted isoforms are part of a growing family of PLA2 enzymeswhose activity leads to the production of several ... stress, and therefore are con-sistent with the peptide& apos;s performance in vivo.MethodsSources and preparation of sPLA2Purified secreted phospholipase A2 group I from thevenom of the Mozambique...
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báo cáo hóa học: " Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice" pot

... NeuroinflammationOpen AccessResearch Inhibition < /b> of < /b> the < /b> alternative < /b> complement < /b> activation < /b> pathway < /b> in < /b> traumatic < /b> brain < /b> injury < /b> by < /b> a < /b> monoclonal < /b> anti-factor < /b> B antibody: a < /b> randomized placebo-controlled study in < /b> miceIris ... expression.Conclusion: Inhibition < /b> of < /b> the < /b> alternative < /b> complement < /b> pathway < /b> by < /b> posttraumatic administration of< /b> a < /b> neutralizing anti-factor < /b> B antibody appears to represent a < /b> new promising avenue forpharmacological attenuation ... extrapolate thesefindings to a < /b> pharmacological model by < /b> targeted inhibi-tion of < /b> the < /b> alternative < /b> pathway < /b> [35]. We therefore used a< /b> newly available, highly specific and potent inhibitor of< /b> the < /b> alternative...
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báo cáo hóa học: " Toll-like receptor 2 -196 to -174 del polymorphism influences the susceptibility of Han Chinese people to Alzheimer’s disease" potx

... SHOR T REPOR T Open Access Toll-like receptor 2 -196 to -174 del polymorphism influences the susceptibility of Han Chinese people to Alzheimer’s diseaseJin-Tai Yu1 ,2 , Shan-Mao Mou1,3†, Li-Zhu ... data suggest that the -196 to -174 del/ del genotype of TLR2 may increase risk of LOAD in aNorthern Han Chinese population.Keywords: Alzheimer’s disease, toll-like receptor 2, polymorphism, association ... 150(37.5) 161(40 .2) 89 (22 .2) 0. 026 461(57.6) 339( 42. 4) 0.009Controls 400 1 72( 43.0) 168( 42. 0) 60(15.0) 5 12( 64.0) 28 8(36.0)ApoEε4(-)AD 26 0 94(36 .2) 104(40.0) 62( 23.8) 0. 027 29 2(56 .2) 22 8(43.8) 0.009Controls...
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Báo cáo hóa học:

Báo cáo hóa học: " Inhibition of histone deacetylation in 293GPG packaging cell line improves the production of self-inactivating MLV-derived retroviral vectors" pdf

... CentralPage 1 of 12(page number not for citation purposes)Virology JournalOpen AccessResearch Inhibition of histone deacetylation in 293GPG packaging cell line improves the production of self-inactivating ... loss of a small part of the R region in the LTR. Their results also suggested a negative interfer-ence of the tyrosinase enhancer on the viral enhancerwhen the latter was retained in the 3'LTR. ... involved in enhanced SINCMV titers. Our results show that treatment of the SINCMV retroviral producer cells with 3 µM TsAresulted in a significant increase in titer indicating that histone deacetylation...
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báo cáo hóa học:" Human cytomegalovirus uracil DNA glycosylase associates with ppUL44 and accelerates the accumulation of viral DNA" potx

... 1 of 14(page number not for citation purposes)Virology JournalOpen AccessResearch Human cytomegalovirus uracil DNA glycosylase associates with ppUL44 and accelerates the accumulation of viral ... part of the DNA replication machinery and that it significantly accelerates the synthesis of genomic DNA. This interpreta-tion of the data is consistent with the early expressionkinetics and the ... [29]. The fact thatpUL114 appears to associate with ppUL44 is intriguing,because of the central role that ppUL44 plays in the synthesis of viral DNA [9,20,21]. These data takentogether with the...
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báo cáo hóa học:

báo cáo hóa học:" Traumatic extremity arterial injury in children: Epidemiology, diagnostics, treatment and prognostic value of Mangled Extremity Severity Score" pdf

... properly cited.Research article Traumatic extremity arterial injury in children: Epidemiology, diagnostics, treatment and prognostic value of Mangled Extremity Severity ScorePhilipp Mommsen*1, ... injury. J Trauma 1997, 43:480-5.doi: 10.1186/1749-799X-5-25Cite this article as: Mommsen et al., Traumatic extremity arterial injury in children: Epidemiology, diagnostics, treatment and prognostic ... lesions of the upper extremity (p < 0.05). Accordingly, there wasno MESS ≥ 7 in patients with an injury of the upper extremity. The initial and definite limb salvage of theupper extremity...
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Báo cáo hóa học: " Research Article Object Tracking in Crowded Video Scenes Based on the Undecimated Wavelet Features and Texture Analysis" pptx

... shown in Figure 3(c).3.3. The temporal tracking The aim of temporal tracking is to locate the object of interest in the successive frames based on the information about the object at the reference ... distribution, and reproduction in any medium, provided the original work is properly cited.1. INTRODUCTION Object tracking is one of the challenging problems in im-age and video processing applications. ... tracking under occlusion can also be found in [19]. In recent years, feature -based techniques in the wavelet domain have gained more attention in object tracking [20–23]. In [20], an object in the current...
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Báo cáo khoa học: "Clostridium difficile-associated diarrhea in radiooncology: an underestimated problem for the feasibility of the radiooncological treatment" doc

... feasibility of the radiooncological therapy in terms of interruption orabandonment of the radiotherapy, change of therapyconcept and the effect on the feasibility of chemother-apy were evaluated.Induced ... at risk of developing CDAD. The aim of this analysis is to determine the incidence of CDAD in radiooncological patients and to find out whatrelevance CDAD has for the feasibility of the radiooncological ... describes an incidence of 0,1% for Europe and an incidence of 0,1%to 2% for the USA [3]. Heinlen et al. could found an incidence of 0,6% for the USA in the year 2003 [28].Especially the patients...
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Báo cáo y học: "Age-specific mortality patterns in Central Mozambique during and after the end of the Civil War" ppt

... AIDS mortality in Central Mozambique in mid-to-late 1990s. Finally, the influx of UN peacekeepers in 1993 with their perceived wealth and the creation of a large commercial sex industry in Beira, ... Child and Maternal Mortality during a period of conflict in Beira City, Mozambique. Int J Epi 1996, 25(2):349-356.13. Coninx R, Dupuy C: Effects of the civil war in Central Mozambique and evaluation ... not begin in Beira until 1996 [15]. During these 10 years of non-monitoring, HIV expandeddramatically in Central Mozambique. By 1996, 17% of the pregnant women in Beira were already infected...
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