... LPS /Aβ- induced inflammatory processes by blocking the expression of proinflammatory cytokine, iNOS, COX-2 and MnSOD genes, and by inhibition of ROS generation and depletion of glutathione in astroglial ... AICARattenuation of LPS- or cytokine /Aβ- induced expression of inflammatory mediators (e.g. iNOS, COX-2 and cytokines) by inhibiting the activation of transcriptionfactors (NFκB and C/EBP) required for induction ... purposes)AICAR inhibits LPS- and Aβ- (25–35) induced expression of iNOS, COX-2, and MnSOD in astrocyte-enriched glial cellsFigure 4AICAR inhibits LPS- and Aβ- (25–35) induced expression of iNOS, COX-2, and...