Báo cáo hóa học: " Retrograde transport pathways utilised by viruses and protein toxins" potx

... 1a and L-type Calcium Channel. Br J Pharmacol 2011, PubMed PMID: 21585344. doi:10.1186/1742-2094-8-117 Cite this article as: Shukla and Sharma: Sinomenine inhibits microglial activation by Ab and ... Chhibber and Jeet Bahadur Singh for their help in the experiments, and Justin Shobe, Mike Sutton and Shara Stough for their thoughts on an earlier version of the manuscript. This wo...

Ngày tải lên: 19/06/2014, 22:20

... immunofluorescence and immunohistochemistry CAV1 and topoisomerase-alpha protein expression in tis- sue and cells was studied by Immunofluorescence and Immunohistochemistry. As shown in Figure 4B and Fig- ure ... binds to and inhibits the activity of several signaling proteins in vitro and in situ, including the EGF and Neu receptors, Src-family kinases (Src/Fyn), PKCs, eN...

Ngày tải lên: 18/06/2014, 15:20

... microtubules and intermediary fila- ments, as well as keratin 5 and 15. We also looked for genes involved in cell adhesion and migration and found integrin alpha 3, integrin beta 2 and intercellular ... FOX (fork- head box G1) and FYN (FYN oncogene related to SRC) and NRCAM (neuronal cell adhesion molecule). The expression data generated by the oligonucleotide array and RT-P...

Ngày tải lên: 18/06/2014, 15:20

... responsive to stimulation by CD66c, CD66de, and CD63 mAbs as evidenced by an increase in adhesion. Similarly, desensitization of neutrophils to stimulation by the CD66ae and CD66c mAbs selectively ... stimulation by the CD66ae mAb and the CD66c mAb, but not by CD66b, CD66de, or CD63 mAbs (Fig 1, panel C). Finally, desensitization to the CD66ae and CD66de mAbs left the cells...

Ngày tải lên: 18/06/2014, 15:20

... contributions FS, and AS have made substantial contribution in the acquisition and alignment of sequences, in the analysis and interpretation of data, and helped to draft the manu- script. LC, BP, PGN, and ... limitations imposed by the limited number of patients analyzed and by the fact that the mature TR rep- ertoire is influenced not only by the coding potential of TR VDJ...

Ngày tải lên: 18/06/2014, 15:20

... fluorophore in UV is present in both viruses and host bacterial protein. Indole group of tryp- tophan residues are major source of UV absorbance and emission in proteins. Tryptophan in pure water ... Assembly. Photochemistry and Photobiology 2004, 80(1):41-46. 4. Alexandra , et al.: Virus Particles and Receptor Interaction Monitored by Fluorescence Spectroscopy. Photochemistry a...

Ngày tải lên: 18/06/2014, 15:20

Ngày tải lên: 18/06/2014, 16:20

... the KCNRG lung protein, followed by the gastric ATPase, AQP-4, GAD65 neural autoanti- gens and finally the Ro52 protein (Figure 2). As evident from the heatmap, several of the ARDS and septic shock ... contributions PDB, NS, SG and AFS conceived of the study. GUM collected the patient plasma samples and provided the clinical characteristics. PDB, SG, KHC and BH analyzed the ser...

Ngày tải lên: 18/06/2014, 16:20

... factor-1 (IGF-1)-induced processing of amyloid-beta precursor protein (APP) and APP-like protein 2 is mediated by different metalloproteinases. J Biol Chem 2010, 285:10223-31. 32. Fan X, Liu Y, ... ECM and reduced cell adhesion. A number of studies have demonstrated that the metalloprotease domain of ADAM 10 can cleave and remodel ECM proteins such as type-IV collagen and CD44 [...

Ngày tải lên: 18/06/2014, 16:20

... Collection and assembly of data. AD Collection and assembly of data. AK Data analysis and interpretation, collection and assembly of data. CP Conception and design, data analysis and interpretation. ... Conception and design, provision of patients, data analysis and interpretation, manuscript writing. PA Conception and design, data analysis and interpretation, manuscript w...

Ngày tải lên: 18/06/2014, 16:20