... 8:113 http://www.jneuroinflammation.com/content/8/1/113 Page 8 of 12 repeat and Ig domain-containing, Nogo receptor-interact- ing protein) [12]. However, due to the findings of NgR1 expression without LINGO-1 ... nsducing subunits of the NgR1 complex remain to be identified. Binding of the NgR1 inhibitory complex by MAIFs leads to activation of intracellular RhoA, thereby resulting...
Ngày tải lên: 19/06/2014, 22:20
... of pathologies. The study findings revealed significant age-related differ- ences in all seven functional mobility tests examined. These findings confirm those of previous studies and indi- cate that when ... at least once/week 378 55.3 Use of walking aid 115 16.8 ≥ 1 fall in the past year 294 43.0 Moderate or marked fear of falling 189 27.9 Journal of NeuroEngineering and Rehab...
Ngày tải lên: 19/06/2014, 08:20
Báo cáo hóa học: " Role of protease-activated receptor-2 on cell death and DNA fragmentation in Helicobacter pylori-infected gastric epithelial cells" ppt
... expression using PAR-2 AS ODN in AGS cells. Additionally, inhibition of PAR-2 activity using trypsin inhibitor increased cell death and DNA fragmentation in H. pylori-infected AGS cells. These results ... suppresses H. pylori- induced activation of MAPK in gastric epithelial cells To determine the role of PAR-2 on the activation of MAPK, the activation of three major MAP...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học:" Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson''''s disease" doc
... SH-SY5Y cells from injury in the presence of neurotoxinsFigure 1 RPE-CM protect SH-SY5Y cells from injury in the presence of neurotoxins. (A) SH-SY5Y cells cultured without rotenone (Control), cells ... significantly improve AIR in 6-OHDA-lesioned rats To demonstrate the RPE cells survival in the host striatum, we performed HE staining and cytokeratin immunostain- ing....
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học: " Human brain endothelial cells endeavor to immunoregulate CD8 T cells via PD-1 ligand expression in multiple sclerosis" pdf
... BBB impairment facilitates the infiltration of peripheral immune cells into the CNS [1]. Infiltrating cells detected within MS lesions include macrophages and T cells. Although CD4 T cells have been established ... [15,21], suggesting distinct regulation of PD- L1 and PD-L2 by endothelial cells in different species and in different organs. Massive infiltration of immune c...
Ngày tải lên: 19/06/2014, 22:20
Tài liệu Báo cáo khoa học: Role for nectin-1 in herpes simplex virus 1 entry and spread in human retinal pigment epithelial cells docx
... changes in the cytoskeleton that may occur during the initial 6 h window of infection. We infected RPE cells with K26GFP [27], and stained cells for F-actin, using phalloidin at 30 min and 6 h postinfection, ... play a role in viral spread by mediating cell-to-cell fusion [32,33], we also decided to examine the role of nectin-1 in the fusion of RPE cells with viral glyco...
Ngày tải lên: 18/02/2014, 14:20
báo cáo hóa học:"Necessary and sufficient condition for the smoothness of intersection local time of subfractional Brownian motions" docx
... proof of Theorem 2. 4. Smoothness of the intersection local time In this section, we consider the smoothness of the intersection local time. Our main object is to explain and prove the following ... spherical coordinates as following s = r cos ϕ 1 , t = r sin ϕ 1 cos ϕ 2 , u = r sin ϕ 1 sin ϕ 2 cos ϕ 3 , v = r sin ϕ 1 sin ϕ 2 sin ϕ 3 . (3.10) 6 E ε ) exists in L...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Human embryonic stem cells hemangioblast express HLA-antigens" pot
... (γ) globin genes and not the adult-type β-globin (Figure 2H). Kinetics of hemangioblast formation in EB culture and characterization of blast cellsFigure 1 Kinetics of hemangioblast formation in EB ... (Sigma) containing BMP-4 and VEGF (50 ng/ml of each) (Invitrogen, CA, US). After 48 hours of incubation, half of the culture media was replaced with the Stemline II media contai...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Circulating endothelial progenitor cells: a new approach to anti-aging medicine?" docx
... first report of a combination of naturally occur- ring molecules from food products altering the levels of circulating EPCs in humans. As seen in Figure 1, an increase in cells expressing VEGFR2 and ... fibrosis [76,77], and inhibit post cardiac infarct remodeling [78]. One caveat of these studies is that definition of EPC was variable, or in some cases a confounding effec...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: "Anti-viral state segregates two molecular phenotypes of pancreatic adenocarcinoma: potential relevance for adenoviral gene therapy" pdf
... phenotype in vivo that could be segre- gated according to the coordinate expression of an inflammatory signature including cytokines, chemokines and angiogenic factors [16,31]. The expression of these Figure ... cultured cell lines; 3) the two phe- notypes reflect a true “ anti-v iral” state capable of inhibiting replication of at least two families of viruses (adeno viruses and...
Ngày tải lên: 18/06/2014, 16:20