Báo cáo hóa học: " Deletion of human metapneumovirus M2-2 increases mutation frequency and attenuates growth in hamsters" potx

... uridine monophosphokinase. Mol. Gen. Genet. 205, 74–81. Ó FEBS 2003 Substrate specificity of human and Dictyostelium UMP-CMP kinase (Eur. J. Biochem. 270) 1789 Reaction of human UMP-CMP kinase with natural and analog ... cellular kinases of nucleoside analogs used in antiviral therapies. The reactivity of human UMP-CMP kinase towards natural substrates...

Ngày tải lên: 08/03/2014, 02:20

... flow cytometry- based pharmacodynamic assays. Here we report the validation of a flow cytometry- based chemokine internalization assay for use in evaluating the effect of a receptor antagonist in ... foundation in which to base the validation of a flow cytometry pharmacodynamic assay and applying the "appropriate" par...

Ngày tải lên: 18/06/2014, 15:20

... human DCs by antineoplastic chemotherapeutic agents in low noncytotoxic concentra-tionsFigure 1 Chemomodulation of phenotype of human DCs by antineoplastic chemotherapeutic agents in low noncyto- toxic ... followed by syngeneic dendritic cell injection in the mouse: findings and implications for human treatment. Urology 2007, 70(6 Suppl):36-41. 31. Sh...

Ngày tải lên: 18/06/2014, 15:20

... Incubation with CP-870, 893 activated B cells, including both memory and naïve B cells, as demonstrated by upregulation of < /b> CD86, CD70, CD40, and MHC class I and II. CP-870, 893 - activated B cells ... including both memory and naïve B cells as defined by the presence or absence of < /b> CD27 expression. We studied the effect of < /b> CP-870, 893...

Ngày tải lên: 18/06/2014, 15:20

... Sigalotti et al., Epigenetics of human cutaneous mela- noma: setting the stage for new therapeutic strategies Journal of Transla- tional Medicine 2010, 8:56 Sigalotti et al. Journal of Translational ... medium, provided the original work is properly cited. Review Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic stra...

Ngày tải lên: 18/06/2014, 16:20

... 2005, and October until November 2005. Measures The Inventory for Assessing the Quality of Life (ILC) This measure was developed in Germany by Mattejat and colleagues as a short and practical assessment ... 14:1573-1584. 7. Chen X, Sekine M, Hamanishi S, Wang H, Gaina A, Yamagami T, Kag- amomori S: Lifestyle and health-related quality of life in Japa- nese school...

Ngày tải lên: 18/06/2014, 22:20

... balance maintenance and arm transport. All participants practiced ten 90-s gaming trials during a single session, followed by a retention test. Arm-postural coordination was analysed using principal ... feasibility of using the custom-made 3D game for retraining of arm-postural coordination disrupted as a result of TBI. Keywords: virtual reality, motor rehabilitation, po...

Ngày tải lên: 19/06/2014, 08:20

... http://www.jneuroengrehab.com/content/6/1/10 Page 15 of 18 (page number not for citation p urposes) Journal of NeuroEngineering and Rehabilitation Review Mechanisms of human cerebellar dysmetria: experimental evidence and current conceptual ... commands, sensorimotor synchronization, maintenance of sensorimotor associations and tuning of the magnitudes of mus...

Ngày tải lên: 19/06/2014, 08:20

... to investigate the effects of intensive arm training on motor performance in four chronic stroke patients using the robot ARMin II. Methods: ARMin II is an exoskeleton robot with six degrees of ... clearly indicate that intensive arm therapy with the robot ARMin II can significantly improve motor function of the paretic arm in some st...

Ngày tải lên: 19/06/2014, 08:20

... unreported genetic instability was observed, resulting in a higher fre- quency of point mutations and random insertions of U nucleotides in poly-U tracts of the rhMPV/ M2-2 genomic RNA. Results Expression of M2-2 ... insertions and point mutations in rhMPV/ M2-2 compared to rhMPVFigure 3 Chromatogram and frequency of A insertions and point mutations in rhMPV/ M...

Ngày tải lên: 20/06/2014, 01:20

... levels of inhibition of viral growth in Hematoxylin/eosin (A-B and G) and fluorescent staining (C-F, H) of EpiGingival tissuesFigure 4 Hematoxylin/eosin (A-B and G) and fluorescent staining (C-F, ... are available for studying HCMV infection. Results: In this report, we studied the infection of HCMV in a cultured gingival tissue model (EpiGingival, MatTek Co.) and invest...

Ngày tải lên: 20/06/2014, 02:20

... Central Page 1 of 6 (page number not for citation purposes) Virology Journal Open Access Research Inhibition of human immunodeficiency virus type-1 (HIV-1) glycoprotein-mediated cell-cell fusion by immunor ... Percent- age fusion was divided into three classes: 56–00% of the surface covered by syncytial = fusion; partial inhibition of fusion: < 10%...

Ngày tải lên: 20/06/2014, 04:20

... purposes) Virology Journal Open Access Research Typing of human rotaviruses: Nucleotide mismatches between the VP7 gene and primer are associated with genotyping failure Mustafizur Rahman* 1,2 , Rasheda ... UV-light. Nucleotide mismatches in the primersFigure 2 Nucleotide mismatches in the primers. The target sequence is the VP7 gene of G1...

Ngày tải lên: 20/06/2014, 04:20

... role in tumor growth and in the induction of T cell dysfunction. Therefore, we studied in murine renal cell carcinoma (RCC) cell lines, the effect of arginase II on tumor cell proliferation and L-arginine ... changes in arginase inhibition, L-arginine depletion and L-ornithine production when nor-NOHA was added to cultures with CL-2 and Renca c...

Ngày tải lên: 10/08/2014, 22:20