Báo cáo hóa học: " Mapping of immunogenic and protein-interacting regions at the surface of the seven-bladed β-propeller domain of the HIV-1 cellular interactor EED" pptx

... contributions JJMH participated in the design of the study, performed the statistical analysis and prepared the manuscript. ESvH carried out the immunohistochemical analyis and quanti- fication of the immunohistochemical ... immunohistochemical data. RV has been involved in the collection of the human post mortem brain material. TA, WS, PE and AJMR participated in...

Ngày tải lên: 19/06/2014, 22:20

... sulfate ; Grid Screen Sodium Chloride Surface representation of the β-propeller domain of EED and protein-interacting regionsFigure 3 Surface representation of the β-propeller domain of EED and protein-interacting ... protein. Mapping of the HIV-1 MA and IN binding sites on the 3D-model of EED core predicted that EED-bound MA and IN ligands woul...

Ngày tải lên: 20/06/2014, 01:20

... study, the mapping technique implicitly assumes that the EQ-5D covers all important aspects of the latent health construct that the ISI is intended to measure. Hence, the strength of the mapping ... a mapping relationship between insomnia-related measures and the EQ-5D. We aimed to estimate the associations between the EQ-5D health state utilities and insom...

Ngày tải lên: 20/06/2014, 15:20

... [14]. The dataset was then divided in two by taking a random sample of 60% of the data and separating that data from the remaining 40% to provide an estima- tion dataset and a validation dataset, ... 1993 and 2001. Results There were 2855 records in the estimation dataset and 1887 in the validation dataset. The estimation and valida- tion datasets had similar distrib...

Ngày tải lên: 20/06/2014, 16:20

... treatment was normalized with that of the untreated cells. Following the sequential treatment of PGSE and TNF-α, we found that 102 upregulated genes and 64 downregu- lated genes were repeatedly ... repeated twice. The ratio of the plant material to the menstruum was 1:10. The resultant extract was concentrated by evaporation and then dried by lyophilization to obtain P...

Ngày tải lên: 18/06/2014, 15:20

... pro- liferation and migration. Phosphorylation of ezrin induces its translocation from the cytoplasm to the plasma membranes of microvillus and confer s the ability of binding to plasma membrane and ... invasion ability of MiaPaCa-2 cells Cell motility ability was examined by dete rmining of the migration rate through a polyethylene filter in the absence of Matrige...

Ngày tải lên: 18/06/2014, 16:20

... each of these treatment groups received an additional daily administration of RU486 IP for 1 week. At the end of treatment, TSLN were isolated and analyzed by flow cytometry for their content of ... proinflammatory tumor killing agents by enhancement of the immune response and alteration of the TSLN microenvironment. Background Prostate canc er is one of the leadin...

Ngày tải lên: 18/06/2014, 16:20

... prime-boost immunization regimens requires a deeper understanding of the mechanism of action of DNA vaccination. A key observation from many studies to date is that interchan- ging the order of vectors ... development for the treatment of diseases such as HIV, other microbes and cancer [11,22-37]. In addition, such protocols offer a more pract ical alternative for active imm...

Ngày tải lên: 18/06/2014, 16:20

... in the perspective they take towards the patient. Gundy and Aar- onson [23] investigated whether or not there are differ- ences in proxy-ratings if the proxy rates the patient taking the patient's ... underestimating patients' QOL. The current study aimed to investigate the relation between ratings of patients and their significant others on QOL assessed with th...

Ngày tải lên: 18/06/2014, 19:20

... 7,582) Lives with mother and father 59.9% Lives with mother and not father 25.7% Lives with father and not mother 7.8% Does not live with mother or father 6.7% Satisfied with quality of life (N=7,606) Strongly ... for the five life domains (rather than the use of single items for each of the life domains), resulted in greater sensitivity to detect these associations. In addi...

Ngày tải lên: 18/06/2014, 19:20