Báo cáo hóa học: " Differential control of CXCR4 and CD4 downregulation by HIV-1 Gag" docx

... receptor downregulation. Results: Here we show that downregulation of the HIV-1 co-receptor, CXCR4, by its ligand SDF- 1, is ESCRT-I dependent. Expression of HIV-1 Gag attenuated downregulation of CXCR4, ... this study, we show that HIV-1 Gag, as well as TSG101, differentially affect the kinetics of downregulation of the HIV-1 co-receptors CXCR4 and CD4. SDF...

Ngày tải lên: 20/06/2014, 01:20

... KCs to change expression patterns of the other KC differentia- tion markers by reducing expression of basal keratins K14 and increasing expression of keratins K1 and K10 (data not shown). These ... KCs Effects of post-transfection treatment of methylcellulose on expression of PV L1 genes in mouse primary KCsFigure 2 Effects of post-transfection treatment of methylcellulo...

Ngày tải lên: 20/06/2014, 01:20

... acquisition of data for NIHSS and mBI, and database management. TGF, JCS, DFM, CC, ISN participated in the acquisition of data for NIHSS and mBI. PAPJ participated in the acquisition of data for NIHSS and ... defined by the presence of a focal neurological deficit of acute onset lasting over 24 hours, confirmed by neuroimaging (computed tomography of magnetic resonance...

Ngày tải lên: 20/06/2014, 15:20

... determination of the given methylation status of the UCHL1 promoter may contribute to the understanding of the role of a differen- tial UCHL1 expression during tumorigenesis and progres- sion of human ... during the differentiation of renal tubules representing the origin of clear cell renal cell carcinoma (RCC) and in the regula- tion of the cell cycle of parietal epith...

Ngày tải lên: 18/06/2014, 15:20

... concen- trations of PLX4032, DMSO vehicle control, or 1 μM of staurosporine as a positive control, for 120 hours. Cells were trypsinized and transferred to FACS tubes and stained with Annexin V-FITC and propidium ... line and the PLX4032-resistant M233 cell line were cultured in different concentrations of PLX4032 for 24 hours and lysates were analyzed by Western blot. b)...

Ngày tải lên: 18/06/2014, 16:20

... C1q with mRNAs extracted from slices (Figure 6a). CD40 , IL-8, and MCSF mRNAs are induced by A β 42 and differentially regulated by A β 10–20 and APV It is known that activated microglia cells ... proliferation and activation, has been shown to be expressed by neurons upon Aβ stimulation [41]. The expression of MCSF was induced in slice culture by Aβ treatment by Day 3 (...

Ngày tải lên: 19/06/2014, 22:20

... differentia- tion, and hypertrophy. One of the ways in which this reg- ulation occurs is through complex control of chondrocyte gene expression. Mechanical loading of cartilage is sensed by chondrocytes ... in a specific part of cartilage, e.g., the hypertrophic region and/ or the osteoar- thritic lesion. Elucidation of the differential expression of type X collagen regul...

Ngày tải lên: 20/06/2014, 00:20

... in Expression of TLR by HFF and Ectocervical tissueFigure 7 Expression of TLR by HFF and Ectocervical tissue. Expression of TLR2, TLR3, TLR4 and TLR9 in cells and tissue was assessed by reverse-transcription ... TLR3 and TLR4 ligands, but not TLR2 or TLR9 ligands, inhibited HCMV infection. Time dependence of TLR stimulation for HCMV inhibition and IL-8 production T...

Ngày tải lên: 20/06/2014, 01:20

... Angeletti* 2 Address: 1 Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok Thailand and 2 Nebraska Center for Virology, School of Biological Sciences, University of Nebraska-Lincoln, ... Merge V E6*I E6 E6MT A V E6*I E6 E6MT GFP Phase Merge B Co-localization of E6s and E6AP in 293T (A) and HaCaT (B)Figure 3 Co-localization of E6s and E6AP in 293...

Ngày tải lên: 20/06/2014, 04:20

... (BioRad) and analyzed by Quantity One software (Bio-Rad) according to manufacturer’s recommendation. The relative density of each ALDH1 band was expressed as a ratio of the density of ALDH1 band and ... facilitate understanding the role of ALDH1 in the ovary and ovarian tumors. Acknowledgements The authors acknowledge Drs. Jacob Rotmensch and Alfred Guirguis of the Departm...

Ngày tải lên: 20/06/2014, 07:20