Báo cáo hóa học: " Thiol-reactive reagents inhibits intracellular trafficking of human papillomavirus type 16 pseudovirions by binding to cysteine residues of major capsid protein L1" pdf
Báo cáo hóa học: " Thiol-reactive reagents inhibits intracellular trafficking of human papillomavirus type 16 pseudovirions by binding to cysteine residues of major capsid protein L1" pdf
... JournalOpen AccessResearch Thiol-reactive reagents inhibits intracellular trafficking of human papillomavirus type 16 pseudovirions by binding to cysteine residues of major capsid protein L1Yoshiyuki ... infectivity of HPV16 PVs (16Pvs) by bind-ing to the L1 cysteine residues. ResultsInfectivity of the 16PVs that have bound to thiol-reactive reagents The 16PVs was found to lose their infectivity ... cysteine residues of 16PVBPEOIA, capable of making a complex with streptavidin,was found to bind to the free thiol of the cysteine residues of L1 of 16PV, which was produced by packaging of areporter...
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Báo cáo sinh học: " Thiol-reactive reagents inhibits intracellular trafficking of human papillomavirus type 16 pseudovirions by binding to cysteine residues of major capsid protein L" pot
... inhibits intracellular trafficking of human papillomavirus type 16 pseudovirions by binding to cysteine residues of major capsid protein L1Yoshiyuki Ishii1, Kazunari Kondo1, Tamae Matsumoto1, ... infectivity of HPV16 PVs (16Pvs) by bind-ing to the L1 cysteine residues. ResultsInfectivity of the 16PVs that have bound to thiol-reactive reagents The 16PVs was found to lose their infectivity ... with anti-HPV16L1 antibody.A16PV + DTNB16PV-L116PV + NEM16PV-BC2h 8h 20h16PV16PV+DTNB20h16PV16PV+NEMTrypsin- +++++ - +++++Incubation (h)0024820002482016PV 16PV+DTNB132K90K55K45K34K25KL1L112...
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báo cáo hóa học: " Ginkgolide B inhibits the neurotoxicity of prions or amyloid-β1-42" pdf
... con-taining amino acid residues 82 to 146 of the human PrP protein (HuPrP82-146), platelet activating factor (PAF),cellular prion protein (PrPC), disease-associated isoform of the prion protein (PrPd), ... SH-SY5Y cells against the toxicity of PAF or arachidonic acidThe toxicity of PrP peptides requires the activation of phospholipase A2 and the subsequent release of neurotox-ins such as arachidonic ... removed by shak-ing (260 r.p.m for 30 minutes). The survival of neuronswas then determined by treating cultures with WST-1.PeptidesPeptides containing amino acid residues 82 to 146 of thehuman...
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báo cáo hóa học: " Quinolinic acid selectively induces apoptosis of human astrocytes: potential role in AIDS dementia complex" ppt
... receptor activa-tion [37,38]. We previously demonstrated that HIV-1proteins Nef and Tat lead to production of high levels of QUIN by human macrophages [14]; that inhibition of QUIN production by ... long-termconsequences of intracranial injections of the excitotoxin,quinolinic acid, as evidenced by GFA immunohistochemistry of astrocytes. Brain Res 1986, 371:267-277.29. Dihne M, Block F, Korr H, Topper ... rechecked by the experimenter and cells classifiedaccording to the following scheme: DAPI staining for totalNumeration of apoptotic astrocytes using immunocytochemistryFigure 2Numeration of apoptotic...
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Báo cáo hóa học: " The simultaneous presence and expression of human hepatitis C virus (HCV), human herpesvirus-6 (HHV-6), and human immunodeficiency virus-1 (HIV-1) in a single human T-cell" pptx
... laboratories. As part of the determinations of host ranges of these viruses, studieswere designed to demonstrate the infection of a single cell by these viruses and to study theconsequences of ... variabledue to a number of factors that affect replication. This hasrelevance to viral protein production that may induce orproduce pathology. How the viruses interact will be thesubject of later ... laboratories at the California Institute of Molecular Medicine (CIMM), Ventura, CA. Freshly iso-lated viruses were used for this study. Stocks of these iso-lates were stored in aliquots of 1...
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báo cáo hóa học:" Genome structure and transcriptional regulation of human coronavirus NL63" ppt
... transcription. The level of transcription of a particulargene has been reported to be inversely related to the dis-tance of a particular TRS to the 3' end of the genome [16- 19].In this study, ... viruses. An outbreak of severeacute respiratory syndrome (SARS) in the spring of 2003led to the rapid identification of SARS-CoV [1,2], which isconsidered to be a distinct member of the group 2 ... the nucleotide count led us to compare thecodon usage of HCoV-NL63 with that of human mRNA(Table 1). The codon usage of HCoV-NL63 differs mark-edly from that of human mRNAs. Third-base choices...
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báo cáo hóa học:" Strategically examining the full-genome of dengue virus type 3 in clinical isolates reveals its mutation spectra" doc
... regions of DENV-3 atthe following nucleotide (nt) positions: 1 to 1199, 540 to 1712, 1259 to 2521, 2171 to 3435, 3142 to 4697, 4124 to 5708, 5443 to 7497, 7246 to 8770, 8501 to 10335, 9991 to 10709. ... proportion of mutations relative to the consensus nucleotide or amino acid sequence for each patient and calculated by dividing the number of mutations relative to consensus by the total number of nucleotides ... derived from mosquito inoculation by C6/36-passaged one virus of patient ID#1H.Table 3: Mean p-distance and ratio of dN to dS per site of amino acid among different domains of the E protein in DENV-3...
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Báo cáo hóa học: " Measuring and analyzing tissue specificity of human genes and protein complexes" potx
... microarrays and consists of a total of 16, 989distinct protein- coding genes.The Exon Array probesets were mapped to Ensemblgenes according to the genomic coordinates of the pro-besets as given ... datawere used to investigate the presence of proteins, protein interactions and protein complexes in different tissues.Our comparison shows that the detection of tissue-specific genes and proteins ... data to investigate the tissue specificity of human gene expression and its biological impact on protein expression and protein interaction networks [1,2]. TheGene Atlas data consists of comprehensive...
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báo cáo hóa học:" The structural and optical properties of GaSb/InGaAs type-II quantum dots grown on InP (100) substrate" docx
... STEM images of GaSb/In0.53Ga0.47As QDs and histogram of the height of GaSb/In0.53Ga0.47As QDs.(a) The AFM image of GaSb/In0.53Ga0.47As QDs, (b) histogram of the height of GaSb/In0.53Ga0.47As ... formation of the InGaAsSb wet-ting layer resulted in the accumulation of individual atomson the surface to form a mound-like structure, due to theintermixing of As and Sb during the growth of GaSb ... height of the quantum dots is mainlyconcentrated to approximately 6 nm. Due to the wellknown ‘tip eff ect’ of AFM, the results of AFM measure-ments cannot describe the precise lateral size of...
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Báo cáo hóa học: " The structural and optical properties of GaSb/InGaAs type-II quantum dots grown on InP (100) substrate" ppt
... el of theInGaAs layer may possibly be higher than the bottom of the conduction band of GaSb QDs. In such circumstance,the light emission intensity of the GaSb QD could bestronger than the type ... advantage of thes e features to accomplish a charge-discharge process of QDs and then to modulate the elec-tric property of a two-dimensional electron gas [2DEG] inQD-FET. In this kind of QD-FET ... transition due to the strongerspatial confine ment of carriers in the QD and the nature of the direct transition type I transition. It may be the rea-son that the PL intensity of the direct...
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