Báo cáo hóa học: " Functional relevance of nonsynonymous mutations in the HIV-1 tat gene within an epidemiologically-linked transmission cohort" pot

... Access Short report Functional relevance of nonsynonymous mutations in the HIV-1 tat gene within an epidemiologically-linked transmission cohort Haran Sivakumaran 1,2 , Bin Wang 3 , M John Gill 4 , ... little in known about selection of mutations in the HIV-1 regulatory genes. One of the major regulatory genes of HIV-1 is tat, which encodes th...

Ngày tải lên: 20/06/2014, 01:20

... selection of multiple nonsynonymous mutations in tat in a unique epidemiologically-linked cohort following transmission of HIV-1. Comparisons of the relative transactivation abil- ities of the Tat ... and R52 participates in the binding of Tat to TAR and is involved in the nuclear local- isation of Tat [18,19]. The strong or total suppression of...

Ngày tải lên: 18/06/2014, 18:20

... (MAX) and absolute minimum (MIN) of the curve of joint movement. Beside this, the mean values of MAX and MIN were considered. For ankle joint, in addition to ROM on sagittal plane, peak of plantarflexion, peak ... direction and is defined as the angle formed with the line of progression and the segment connecting the marker on the V metatar- sal joint and the marke...

Ngày tải lên: 19/06/2014, 10:20

... acquisition of data, analysis and interpretation of data, and drafted the man- uscript. MDM contributed to the study design, acquisition of data, analysis and interpretation of data, and revision of the ... undergo regularly training (and assessment) in order to maintain these standards. Background The mining industry has one of the highest occupational rates of seri...

Ngày tải lên: 20/06/2014, 00:20

... help t o determine the nature and direction of the ongoing strategy in the fight against doping in ten- nis: 1) the overall incidence of doping offences is low; 2) the abuse of EPO and growth hormone ... rmance - enhancing and damaging to health [5]. The Tennis Anti-Doping Program h as been conduct- ing ’out -of- competition’ testing since its creation in 1993. The r...

Ngày tải lên: 20/06/2014, 00:20

... manuscript. YNL is the co-supervisor who participated in the data analysis and drafting of the manuscript. XDS contributed in the planning of the experimental program and in discussing of carbon sphere ... growth in size of the cross-linked furanic species eventually results in the precipitation of the molecular clusters out of the solution into the...

Ngày tải lên: 20/06/2014, 23:20

... reported an improvement when using a hierarchical organization of the detection pro- cess. One of the most important decisions when using this kind of architecture lies in the orderings of the detection ... Gopalkrishnan, Speaker, environment and channel change detection and clustering via the Bayesian information criterion, in Proceedings of DARPA Broadcast News Tra...

Ngày tải lên: 21/06/2014, 02:20

... water-soluble organic substances and insoluble carbonaceous solids. The soluble organic substances ha ve been the focus of early research, and understanding of the chemical reaction process and the products ... section of the sample, capturing both populations of the large and small spheres. Micrograph (f) shows the details of the interior of the carbonaceous sph...

Ngày tải lên: 21/06/2014, 17:20

... following superinfection with all of the other viruses, including the ICP4-deficient mutant d120, despite the fact that ICP4 is stringently required for expres- sion of VP16 and other HSV E and L genes ... activates transcription of the IE genes. Four of the IE proteins (ICP0, ICP4, ICP22 and ICP27) then serve to drive further progression into the lytic program. Three of...

Ngày tải lên: 20/06/2014, 04:20