Báo cáo hóa học: " Genetic incorporation of the protein transduction domain of Tat into Ad5 fiber enhances gene transfer efficacy" ppt

... Access Research Genetic incorporation of the protein transduction domain of Tat into Ad5 fiber enhances gene transfer efficacy Tie Han †1 , Yizhe Tang †1 , Hideyo Ugai 1 , Leslie E Perry 1 , Gene P Siegal 2,4 , ... improve the gene transfer effi- cacy of Ad 5 vectors by genetic modification of the fiber knob domain with a PTD tat motif. Our...

Ngày tải lên: 20/06/2014, 01:20

... 11 (page number not for citation purposes) Virology Journal Open Access Research Genetic incorporation of the protein transduction domain of Tat into Ad5 fiber enhances gene transfer efficacy Tie ... re-targeting Ad5 vector via the PTD tat motif would improve the efficacy of Ad5- mediated gene delivery. Results: In this study, we genetically incorpo...

Ngày tải lên: 18/06/2014, 18:20

... that these two transmembrane domains are essential for the expression of 3a on the cell surface. It is possible that the aberrant nature of the oligo(T) tract in the 3a gene is akin to that of the ... that they point towards the existence of quasispecies within a given population of SARS-CoVs. As deduced from their study of sequence variation of the spike gene...

Ngày tải lên: 20/06/2014, 04:20

... value of m, denoted , maximizes the power of the adaptive Neyman statistic [70]. The maxi- mum statistic value is written as, where Var(E 2 ), is the variance of the square of the ele- ments of ... procedure is the iterative minimization of the sum -of- squared criterion J, where N is the number of sample curves, T is the time interval of relevance, w i (·)...

Ngày tải lên: 19/06/2014, 10:20

... eligible for the protocol. The majority of these patients were presenting on the 1st or 2nd day of fever (Figure 2). Of the 113 AUFI patients who presented within the first 2 days of fever, 57.5% ... defervesced out of 113 patients) pre- senting on the 1st or 2nd day of fever. Antimicrobi al therapy was prescribed to 35 of the 113 AUFI patients who initially presen...

Ngày tải lên: 21/06/2014, 00:20

... properties of the stacks, which could reduce the reliability of the MOS devices due to the weaker dielectric strength of the grain boundaries. Finally, the influence of the environment conditions on the ... correspond to the BD spots. The table in the figure shows the maximum current and area of the BD spots generated on each sample. Note that, for the am...

Ngày tải lên: 21/06/2014, 06:20

... |z|≤1} denote the fields of complex, real numbers, the set of natural numbers, the unit circle, the open unit disc, and the closed unit disc, respectively. The symbol F denotes a field that can be either ... let GA denote the set of all invertible elements of A. We define the spectrum of an element f of A to be the set {λ ∈ F : λ1 − f/∈ GA} and denote it by σ f...

Ngày tải lên: 21/06/2014, 07:20

... B which is not a diametral point of B. The following is a version of Kirk’s seminal theorem (cf. [4, Theorem 4.1]) which does not require the convexity of the domain. Now, for any x ∈ Y we get r(c, ... property (A). Theorem 4.8 completes the proof.  The following is an extension of Kirk’s theorem [4, Theorem 4.1] for isome- tries. Theorem 4.10. Let Y be a nonempty and wea...

Ngày tải lên: 21/06/2014, 17:20

... ,gk T . Then we can see that the critical point of J 1 is just the solution to the following system of linear algebraic equations: Mu − G  0. 4.50 By using the theory of linear algebra, we have the ... Clearly, u is a critical point of J. This completes the proof of Theorem 4.1. Theorem 4.2. Suppose that fn, z satisfies the assumptions P 1 , P 2 , and P 3...

Ngày tải lên: 21/06/2014, 20:20

... is of service to the above approaches in enhancing the veridity of the readings of the fused volumetric similarity operators. Another future direction of this work is in the integration of the ... evaluation of the patch operator using the first two frames of the “Venus” middlebury sequence. In the left figure, an image of the binocular pair is shown with...

Ngày tải lên: 21/06/2014, 22:20