Báo cáo hóa học: " Characterization of vaccinia virus A12L protein proteolysis and its participation in virus assembly" ppt

... and pulse chase of A12L proteinFigure 3 Kinetic analysis and pulse chase of A12L protein. A. To determine kinetic analysis of proteolytic processing of A12L, BSC-40 cells were infected with VV ... purposes) Proteolysis of A12LFigure 5 Proteolysis of A12L. In order to characterize the proteolytic processing of A12L, we examined the utilization of each AG/X s...

Ngày tải lên: 18/06/2014, 18:20

... any of statins in MS therapeutics. In a study of 30 MS patient s, statin t reatm ent resulted inasignificantdecreaseinthenumberandvolumeof CEL on serial monthly MRI [39]. A post hoc analysis of the ... enlarging T2-hyperintense lesions over 2 years [40]. The STAYCIS trial to assess sta- tin treatment in slowing the conversion of CIS did not meet its primary endpoint [41]. The...

Ngày tải lên: 19/06/2014, 22:20

... participated in the design of the study and car- ried out the experiment; PD participated in the coordination of the study; SM conceived of the study, and participated in its design and coordination. All ... upper limb kinetic and kinematic behaviors were analyzed in young and elderly subjects performing pointing movements while interacting with a velocity dependent...

Ngày tải lên: 19/06/2014, 08:20

... evaluated. Twenty five l of erythrocyte sample was added to each of a series of 2.5 ml saline solutions containing 0.0 to 0.8 g% of NaCl. After gen- tle mixing and standing for 15 min at room tempera- ture, ... loading of pravastatin into erythrocytes was directly proportional with increase of drug concentration in the incubation medium, in the 2-10 mg/ml concen- trati...

Ngày tải lên: 25/10/2012, 11:10

... gigas [5]. Interestingly, this protein, named C. gigas chitinase-like protein 1 (Cg- Clp1) was found to be involved in the control of growth and remodelling processes in a manner similar to its YKL-40 ... together chitinases and proteins devoid of catalytic activity due to the substitution of a critical amino acid in the cata- lytic centre. This latter singular class of...

Ngày tải lên: 19/02/2014, 00:20

... sequence, both in the amino terminus. TS, composed of residues T169–T186, resides in the carboxy-extension and is augmented in threonine and serine. Deletion of R had more in uence than removal of G on ... proposal, the protein pro- tects citrate synthase against heat-induced aggregation and inactivation of its enzymatic activity and shields insulin from dithiothrei...

Ngày tải lên: 30/03/2014, 20:20

... whole proteins or virus- like particles; recombinant viruses/bacteria/DNA encoding tumor Ag genes; or cells expressing tumor Ags. So far, tumor Ag vaccination in clin- ical trials has had disappointing ... design of assays to reflect and validate in vivo tumor killing mechanisms is challenging. The in vitro assay may be used for the initial screen, and multiple tumor cells, doses...

Ngày tải lên: 18/06/2014, 15:20

... shown that selected sigma-2 ligands are capable of inducing apoptosis in a multitude of human and murine cancer cells lines and in animal models of cancer including pancreas cancer [12,13,15]. The ... representing standard error of the mean. The sigma-2 ligand, SV119, combined with gemcitabine sup-presses tumor growth and increases survival in model pan-creatic adenocarcin...

Ngày tải lên: 18/06/2014, 15:20

... [2,5,7]. The RNA binding motif protein 3, RBM3, is a glycine rich protein containing a RNA-recognition motif (RRM) through which it binds to both to DNA and RNA [8]. Proteins containing specific RRMs ... implicated in cisplatin resistance, i.e. decreased drug uptake, insufficient DNA-binding of the drug, increased DNA-repair of cisplatin adducts and fail- ure of induction of...

Ngày tải lên: 18/06/2014, 16:20

... continuous variables age, years since living in Germany, and years of schooling, analysis of variance (ANOVA) showed that life style was significantly influ- enced by years of schooling in both ... Voss U, Kolling T, Heidenreich T: Role of Monitoring and Blunt- ing Coping Styles in Primary Insomnia. Psychosom Med 2006, 68:110-115. 12. Miller S: Monitoring and blunting: val...

Ngày tải lên: 18/06/2014, 19:20