Báo cáo hóa học: " Vaccinia virus A12L protein and its AG/A

Báo cáo sinh học: " Vaccinia virus A12L protein and its AG/A proteolysis play an important role in viral morphogenic transition potx

... the A12L protein during VV morphogenic transitions and regulation of A12L proteolysis. Conclusion By demonstrating that A12L protein and its cleavage at an N-terminal AG/A play an important role ... [7,8]. L4R, a DNA binding protein, plays an essential role in virus replication, being involved in an early stage of infection such as early tran- scri...

Ngày tải lên : 18/06/2014, 18:20

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Báo cáo khoa học: Nuclear aggregates of polyamines are supramolecular structures that play a crucial role in genomic DNA protection and conformation potx

... genomic DNA preincubated with three differ- ent concentrations (1, 50 and 150 l M) of spermine (lanes c, c¢ and c¢¢), spermidine (lanes d, d¢ and d¢¢) or putrescine (lanes e, e¢ and e¢¢) and then exposed ... NAP (s-NAP; lanes c and c¢), medium-size NAP (m-NAP; lanes d and d¢) or large- size NAP (l-NAP; lanes e and e¢) and exposed to DNase I. Controls were the whole genomic D...

Ngày tải lên : 23/03/2014, 15:20

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Báo cáo hóa học: " Fowlpox virus recombinants expressing HPV-16 E6 and E7 oncogenes for the therapy of cervical carcinoma elicit humoral and cell-mediated responses in rabbits" pot

... cell-cycle regulatory proteins p53 and p105Rb, leading to transfor- mation and carcinogenesis [2], facilitate cell immortalisa- tion in primary human keratinocytes [3], increase genomic instability [4], and maintain ... Westmoreland D, Evans AS, Adams M, Stacey SN, Boursnell ME, Rutherford E, Hickling JK, Inglis SC: A recombinant vaccinia virus encoding human papillomavirus typ...

Ngày tải lên : 18/06/2014, 16:20

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báo cáo hóa học: " Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein b" potx

... ratio between the intensity of the protein of interest band and the loading control protein band (b-actin). Quantitative real time PCR (qPCR) mRNA expression was determined in mouse mixed glial cells ... and participated in the statistical analysis. JSa conceived and coordinated the study and drafted the manuscript. All authors critically revised and approved the final manus...

Ngày tải lên : 19/06/2014, 22:20

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báo cáo hóa học:" Protective CD8+ T-cell responses to cytomegalovirus driven by rAAV/GFP/IE1 loading of dendritic cells" pdf

... study and revised and drafted the manuscript. IDD participated in the design of the study and revised and drafted the manuscript. WMK participated in study design and coordination and revised and ... recognizing the 72 kD immediate early protein and glycoprotein B expressed by recombinant vaccinia viruses. J Exp Med 1988, 168:919-931. 19. McLaughlin-Taylor E, Pande H...

Ngày tải lên : 18/06/2014, 15:20

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báo cáo hóa học:" Assessing the clinical utility of measuring Insulin-like Growth Factor Binding Proteins in tissues and sera of melanoma patients" potx

... this system include the ligands IGF1 and IGF2, their cell surface tyrosine kinase receptors IGF1R and IGF2R, and seven IGF binding proteins (IGFBP). IGF1R has been shown to play a role in a number ... Cohen P: Com- bination therapy of insulin-like growth factor binding protein-3 and retinoid X receptor ligands synergize on prostate cancer cell apoptosis in vitro and in v...

Ngày tải lên : 18/06/2014, 15:20

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báo cáo hóa học:" Announcing the Tumor Immunology and Biological Cancer Therapy section (edited by iSBTc) of the Journal of Translational Medicine" ppt

... iSBTc Executive Office, Chloé Surinak monitors and supports the subsection interactions with the iSBTc leadership, its membership and BioMed Central; Tara Withington as Executive Director of ... Nurse, Cancer Research UK Your research papers will be: available free of charge to the entire biomedical community peer reviewed and published immediately upon acceptance cited in PubMed...

Ngày tải lên : 18/06/2014, 15:20

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báo cáo hóa học:" yuDetecting the percent of peripheral blood mononuclear cells displaying p-STAT-3 in malignant glioma patients" pot

... many malignancies, the signal transducer and activator of transcription 3 (STAT-3) plays an integral role in modulating oncogenesis, inhibiting apoptosis, and suppressing immunity [1,2]. STAT-3 has been ... review board of M. D. Anderson Cancer Center, and informed consent was obtained. Since M. D. Anderson Cancer Journal of Translational Medicine 2009, 7:92 http://www.translation...

Ngày tải lên : 18/06/2014, 15:20

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Báo cáo hóa học: " Human cord blood progenitors with high aldehyde dehydrogenase activity improve vascular density in a model of acute myocardial infarction" ppt

... of 11 ALDH hi Lin - transplanted animals (Figure 2) and in four of six ALDH lo Lin - transplanted animals (data not shown). The human engraftment in the ALDH hi Lin - transplanted animals was generally ... ALDH lo Lin - ,andALDH hi Lin - )on the day following surgery (day 0) and again at one and four weeks post transplantation. All treatment groups had similar sized infarcts at the...

Ngày tải lên : 18/06/2014, 16:20

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Báo cáo hóa học: " Prognostic significance of Oct4 and Sox2 expression in hypopharyngeal squamous cell carcinoma''''" doc

... immunohistochemical staining work, NG, XSX and YL analyzed results. TK and WHH conceived of the study, participated in its design and coordination and helped to draft the manuscript. All authors read and approved ... cell carcinoma Nan Ge 1,2† , Huan-Xin Lin 1,2† , Xiang-Sheng Xiao 1,3† , Ling Guo 1,4 , Hui-Min Xu 1,2 , Xin Wang 1,2 , Ting Jin 1,2 , Xiu-Yu Cai 1,2 , Yi Liang 1 ,...

Ngày tải lên : 18/06/2014, 16:20

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Báo cáo hóa học: " Vaccinia virus A12L protein and its AG/A proteolysis play an important role in viral morphogenic transition" pdf

Báo cáo sinh học: " Vaccinia virus A12L protein and its AG/A proteolysis play an important role in viral morphogenic transition potx

Báo cáo khoa học: Nuclear aggregates of polyamines are supramolecular structures that play a crucial role in genomic DNA protection and conformation potx