... used as an irrelevant negative control.Statistical analysesStatistical analyses were performed using a one-wayANOVA parametric test and Bonferroni/Newman-Keulsanalysis of variance using the ... 347:1523-1527.23. Adams M, Borysiewicz L, Fiander A, Man S, Jasani B, Navabi H, Lipetz C, Evans AS, Mason M: Clinical studies of human papilloma vaccines in pre-invasive and invasive cancer. Vaccine 2001, ... p53 and p105Rb, leading to transfor-mation and carcinogenesis [2], facilitate cell immortalisa-tion in primary human keratinocytes [3], increasegenomic instability [4], and maintain the transformedphenotype...