báo cáo hóa học:" Post-traumatic flexion contractures of the elbow: Operative treatment via the limited lateral approach" doc
báo cáo hóa học:" Highly efficient transduction of human plasmacytoid dendritic cells without phenotypic and functional maturation" docx
... pseudo- type at MOI of 18 to transduce the pDC cell line, and eval- uated the expression of GFP under the control of different promoters such as the ubiquitous PGK promoter, the hematopoietic cell-specific ... to evaluate the immunogenicity of the vector preparations and the specificity and safety of promoters used in gene therapy protocols. Competing interests The...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: " Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood" pptx
... epithelial cells [16-18]. The activities of IL21 have been shown to be highly dependent on the lineage of the target cell, the activation state of the target cell and the presence of other co-stimulators ... biomarker movement dur- ing the treatment period, but it would not show direct linkage between the movement of the biomarker and the engagement of the...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học:" Anti-angiogenic effect of high doses of ascorbic acid" pptx
... metabolism of cells or number of cells. The level of metabolic activity was decreased on 20% for concentra- tions of AA 100–300 mg/dl, but there was no loss of the cells' viability. These experiments ... invasive [45]. As the result, angiogenesis is dependent of the level of nitric oxide, which has an effect on the migration and specific motivity of the endoth...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" In vitro generation of cytotoxic and regulatory T cells by fusions of human dendritic cells and hepatocellular carcinoma cells" docx
... demonstrating the induction of antigen-specific CTL and the generation of Treg by fusions of DCs and HCC cells. The local tumor-related factors may favor the generation of Treg through the inhibition of ... unfused mixture of both DCs and the HCC cells failed to detach the HCC cells (Fig- ure 3A). To assess whether the exposure of HCCsp affects the stim- ulatin...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Whole blood assessment of antigen specific cellular immune response by real time quantitative PCR: a versatile monitoring and discovery tool" potx
... cells. In line with these data, the extent of the increased expression of these genes was strictly dependent on the number of spiked gp100 280–288 specific CTL. Most importantly, these results indicate ... groups of vaccinated individuals. On the other hand, the power of this method as discovery tool should also be underlined. Our data document for the first time that i...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells" pptx
... accumulation in these cells, through the uptake of oxLDL/LDL, is believed to be of fundamental importance to the etiology and pathogenesis of atherogenesis and atherosclerosis and other chronic inflammatory ... with the RNA Nano-chip (Agilent), using the RIN (RNA Integrity Number) algorithm [30] provided with the instrument software. For these samples, the mean RIN ranged fr...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Enhanced serum concentrations of transforming growth factor-beta1 in simple fatty liver: is it really benign?" pot
... draft- ing the manuscript. GT conceived of the research, was the main investigator and the coordinator of the study, made the statistics and drafted the manuscript. All authors read and approved the ... this entity are the same ones that determine the more severe form. The key process in the progression of NAFLD from the very beginning to the end is fibrosis....
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells" docx
... experiments, analyzed the data, and assisted with the preparation of the manuscript. HW synthesized and performed the prelimi- nary characterization of the functionalized dendrimers. KRB assisted with the confocal ... less defective BBTB of the smallest gliomas within the size range of brain tumors in our study (Figure 3B). In the case of the largest RG-2 gliomas...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Phase II trial of Modified Vaccinia Ankara (MVA) virus expressing 5T4 and high dose Interleukin-2 (IL-2) in patients with metastatic renal cell carcinoma" pot
... Biomed- ica. The funding sources had no role in the study design, collection, analysis, or interpretation of the data, or in the writing of the report. They also had no access to the raw Table ... survival (OS) was calculated by the method of Kaplan-Meier, log rank test. OS was calculated from the first date of treatment to date of death, or last known date alive....
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Generation in vivo of peptide-specific cytotoxic T cells and presence of regulatory T cells during vaccination with hTERT (class I and II) peptide-pulsed DCs" pot
... commence. The frequency of these events are well within the probability of documented occurrence (about 10%)[91,92]. The third aim of our study was to document the presence of T regs and their relationship ... individual patients, rather than patient groups. Maintaining the levels of TAAg-specific CD8+ T cells in the circulation is the summation of the capacity to...
Ngày tải lên: 18/06/2014, 15:20