báo cáo hóa học:" SPECT/CT-plethysmography – non-invasive quantitation of bone and soft tissue blood flow" ppt
báo cáo hóa học:" In vitro generation of cytotoxic and regulatory T cells by fusions of human dendritic cells and hepatocellular carcinoma cells" docx
... coordination, and preparation of this manuscript. SK, MM, AT, EN, and, YN prepared reagents and PBMCs. SH, HK, and YS prepared fusion cells and performed vac- cination of the patient. TO, KF, JG, and HT ... high levels of IFN-γ pro- duction and lysis of the CEA- and/ or WT1-positive targets restricted in HLA-A2 and/ or HLA-A24. Interestingly, fusions of immature DCs g...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors" ppt
... the blood half-lives of Gd-G7 and Gd-G8 dendrimers com- pared to those of the Gd-G5 and Gd-G6 dendrimers. The blood half-lives of Gd-G7 and Gd-G8 dendrimers were shorter than those of the Gd-G5 and ... gliomas and define the upper limit of pore size within the BTB of brain tumors and peripheral tumors. We determined the differences in the permeability of the BTB...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: " Assessing agonistic potential of a candidate therapeutic anti-IL21R antibody" pptx
... potential of Ab-01 was assessed by measuring expression levels of cytokine storm-associated and IL21 pathway genes in blood of cynomolgus monkeys before and after IV administration of Ab-01. Results: ... et al. Journal of Translational Medicine, in press), and report here on the levels of these biomarkers in blood from monkeys collected before and after high dose IV...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " A working model of stroke recovery from rehabilitation robotics practitioners" pptx
... Plains, NY, USA, 3 Department of Neurology, University of Maryland, School of Medicine, Baltimore, MD, USA and 4 Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, ... spontaneously and continues imperfectly, depends on a myriad of biological and social/ economic factors: age, gender, physical and mental health, size and location of les...
Ngày tải lên: 19/06/2014, 08:20
báo cáo hóa học:" Anti-angiogenic effect of high doses of ascorbic acid" pptx
... number of intact tubes and closed loops for control wells, wells with low concentra- tions of AA (1 0–5 0 mg/dl), and wells with high concen- trations of AA (10 0–3 00 mg/dl). Effect of high doses of ... high-concentrations of AA (post intravenous administration of 15 g, 30 g, and 60 g) and time of expo- sure were established. The infusion of 15 g of ascorbic a...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Enhanced serum concentrations of transforming growth factor-beta1 in simple fatty liver: is it really benign?" pot
... Normal values were in males 2 0–3 70 ng/mL and in females 1 0–1 50 ng/ mL. The inter-assay coefficients of variation were 4.2%, 5.1% and 6.6% at the concentrations of 37, 221 and 340 ng/mL, respectively, ... 3.21.4 3.41.5 Median Range Median Range Median Range BMI‡ 26 2 2–3 0 29 2 7–3 2 29 2 7–3 2 Fibrosis score 1 1–3 1 1–2 US steatosis Score 2 1–3 1 1–3 CHC, chr...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells" docx
... Institute (NCI), and the Radiology and Imaging Sciences Program (CC). We thank Guofeng Zhang of the Lab- oratory of Bioengineering and Physical Science (NIBIB) and Yide Mi of the Radiology and Imaging ... within blood and glioma tissue over time following intravenous Gd-dendrimer infusions at doses of 0.03 mmol Gd/kg bw and 0.09 mmol Gd/kg bwFigure 2 Gd concentratio...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Phase II trial of Modified Vaccinia Ankara (MVA) virus expressing 5T4 and high dose Interleukin-2 (IL-2) in patients with metastatic renal cell carcinoma" pot
... MVA-5T4 and IL-2. (B) Overall survival of stable (solid line) and progressive (dashed line) disease patients. Numbers of patients at risk at 8, 20 and 28 months are shown below the graph. Journal of ... surgical resection; 2 patients had complete regression of all metastatic disease (lungs and bone) at initial follow-up and underwent nephrec- tomy of primary tumors, 1 pa...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Highly efficient transduction of human plasmacytoid dendritic cells without phenotypic and functional maturation" docx
... (CD123) and the CD4 [18]. Moreover, as a hallmark of pDC, these cells are BDCA2 and BDCA4 (type II C lectin)-positive and CD11c- and CD1a-negative. Trypan blue exclusion and cell counting of LV and ... con- centration of 2–5 × 10 6 of cells per 20 0–5 00 μl of medium. After 3 hours at 37°C, cells were placed in com- plete medium and analysed by flow cytometry betwe...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Generation in vivo of peptide-specific cytotoxic T cells and presence of regulatory T cells during vaccination with hTERT (class I and II) peptide-pulsed DCs" pot
... DCTs and DCTIs have an optimal antigen uptake capacity and upregulation of CD86, CD40 and class I, but low levels of CD83, as is expected of non-terminally mature DCs. The phenotypic profile of ... ME: conception and logistics of the study. MMA, CV, SS, RAR, SC AJM: vac- cination of patients, acquisition of samples and genera- tion of data. MMA, AJM, NRH, JB, FF: pre...
Ngày tải lên: 18/06/2014, 15:20