... only in the spatial- temporal parameters of gait but also in the joint motion. Accordingly, the findings obtained from the kinematic analysis of gait performed here should help to define the treatment ... authors of this paper have any conflict of interest in relation to any sources of any kind pertinent to this study. No commercial party having a direct financial in...
Ngày tải lên: 19/06/2014, 08:20
... was recorded. The time of the first positively moving zero- crossing marks the beginning and the next positively mov- ing zero-crossing marks the end of the given cycle. The inverse of the cycle ... conductance of an individual channel, increas- ing the number of channels, or increasing the probability that a channel is open. Any combination of these changes wo...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" GJB2 mutation spectrum in 2063 Chinese patients with nonsyndromic hearing impairment" pptx
... found in two Hui patients. The common Cau- casian mutation, c.35delG was mainly detected in the minorities of Xinjiang, and accounted for almost half of the GJB2 mutant alleles in minorities of Xinjiang ... for minorities in Xinjiang, testing of Caucasian c.35delG mutation should be included. In patients with Maan ethnic background, sequencing of the GJB2 coding...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Aberrant expression and potency as a cancer immunotherapy target of alpha-methylacyl-coenzyme A racemase in prostate cancer" pptx
... sequence of this protein and analyzed to determine their binding affinities to HLA-A24. By stimulating patient's PBMCs with the peptides, specific CTLs were successfully induced in 6 of 11 patients. ... carrying the HLA-A24 binding motif (Figure 3A). Next, we assessed their binding affinities to HLA-A24 molecules by a bind- ing assay using TAP-deficient T2 cells transfected wit...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Survivin gene levels in the peripheral blood of patients with gastric cancer independently predict survival" doc
... tested four biomarkers, two of the presence, ad two of the aggressiveness of the tumor, and one of these, the Survivin, add independent prognos- tic power to the TMN staging system. This might ... patients' OS. The hazard ratio (HR) associated with Survivin levels indicates the increase in risk of death for 100 fold increase in Survivin expression (Table 3...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: " Three agonist antibodies in combination with high-dose IL-2 eradicate orthotopic kidney cancer in mice" pptx
... activity resulting from inclusion of IL-2 in therapy, we determined the relative proportions of activated T cells in tumor-draining lymph nodes. This was achieved by determining the ability of T cells, ... efficacy observed in subcutaneous models following immuno- therapy may not extend to tumors in other locations. The investigation of rationally designed combination im...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Non-monotonic changes in clonogenic cell survival induced by disulphonated aluminum phthalocyanine photodynamic treatment in a human glioma cell line" pot
... state and also involved in the production of singlet oxygen [43]. High intracellular concentrations of the sensitizer may also result in an inner filtering of light contributing to the reduced photodynamic ... kinetics of AlPcS 2 following incubation of cells with AlPcS 2 in HBSS for different time intervals showed rapid and linear increase in the accumulation of...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Effective knowledge management in translational medicine" doc
... groups and focusing also on the management and mining of the data emanating from integrative settings crossing the drug discovery and development stages. One of the deli- verables of this enhanc ... validation of the primary findings or to novel discoveries such as in the case of meta-analysis of multiple datasets. The burden of deconvoluting the phenotypes fro...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " First-line chemoimmunotherapy in metastatic breast carcinoma: combination of paclitaxel and IMP321 (LAG-3Ig) enhances immune responses and antitumor activity" pptx
... B). The monocyte gain of function calculated as the mean of the percentage increases of each of the eight activation markers in Figure 3A is plotted as a function of the p ercentages of change in ... a gain of function. In the 1.25 mg-group, 28% of patients expressed a gain of function at D170 compared to D1 while 83% of patients in the 6.25 mg group...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Endotoxin and CD14 in the progression of biliary atresia" ppt
... from the circulation within a few minutes of intravenous injection, and the majority of LPS is traced to the liver [6,7]. In addition to clearing LPS, the liver also responds to the presence of ... damaging endotoxemia occur frequently in patients with BA. The aim of this study was to investigate endotoxin levels in patients with BA and the relation of these leve...
Ngày tải lên: 18/06/2014, 16:20