báo cáo hóa học: " Comfort in big numbers: Does over-estimation of doping prevalence in others indicate self-involvement?" doc

Báo cáo hóa học: " HBVRegDB: Annotation, comparison, detection and visualization of regulatory elements in hepatitis B virus sequences" potx

Báo cáo hóa học: " HBVRegDB: Annotation, comparison, detection and visualization of regulatory elements in hepatitis B virus sequences" potx

... The functions of Enh1 and EnhII were demonstrated for the HBV ayw subtype [4]. Protein bind- ing sites. DNA binding sites within the central core domain of Enh I. Binding sites of C/EBP, p53, ... base per year [8]. This results in a quasi-species infecting a single individual and may result in some DNA sequences from an individual not being rep- resentative of the 'fittest&ap...

Ngày tải lên: 20/06/2014, 01:20

10 461 0
báo cáo hóa học:" Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke" pdf

báo cáo hóa học:" Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke" pdf

... neuroserpin decrease. All determinations were carried out in a laboratory blind to the clinical outcome and neuroimaging findings. Endpoints The primary endpoint was the decrease of neuroserpin levels ... obtained after investigating neuroserpin effects using an in vitro model of brain ischemia [40]. The information reported here regarding b iomarkers might be relevant to evaluate the...

Ngày tải lên: 20/06/2014, 03:20

7 404 0
báo cáo hóa học: " Comfort in big numbers: Does over-estimation of doping prevalence in others indicate self-involvement?" doc

báo cáo hóa học: " Comfort in big numbers: Does over-estimation of doping prevalence in others indicate self-involvement?" doc

... purposes) Journal of Occupational Medicine and Toxicology Open Access Research Comfort in big numbers: Does over-estimation of doping prevalence in others indicate self-involvement? Andrea Petróczi* 1,2 , ... thus providing preliminary evidence in support of the FCE concept in relation to doping. Implications of the hypothesis: The presence of the FCE i...

Ngày tải lên: 20/06/2014, 00:20

8 264 0
báo cáo hóa học: " Increased circulating leukocyte numbers and altered macrophage phenotype correlate with the altered immune response to brain injury in metallothionein (MT) -I/II null mutant mice" doc

báo cáo hóa học: " Increased circulating leukocyte numbers and altered macrophage phenotype correlate with the altered immune response to brain injury in metallothionein (MT) -I/II null mutant mice" doc

... response present in MT-I/II -/- mice occurs in later stages of brain injury. The significant findings of increased T cell i nfiltrate into the injury site, increased levels of IL-2, prolonged ... compare the number of T cells infiltrating the injury site in wild type and MT-I/II -/- mice. Analysis of the numbers of leukocytes in circulatio n in the days follow- ing brain...

Ngày tải lên: 19/06/2014, 22:20

11 460 0
báo cáo hóa học:" Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells" pot

báo cáo hóa học:" Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells" pot

... scored on a four level scale (0 = no staining, 1 = weak staining, 2 = moderate staining, 3 = intense staining) by a GU patholo- gist. Results Expression Profiling of Ovarian Cancer Patients We sought ... Aurora-A staining of TMA core of benign ovarian tissue (20×). (G) Aurora-A staining of TMA core of ovar- ian carcinoma with adjuvant chemotherapy (20×). Journal of Translational M...

Ngày tải lên: 18/06/2014, 15:20

13 475 0
báo cáo hóa học:" Human fallopian tube: a new source of multipotent adult mesenchymal stem cells discarded in surgical procedures" potx

báo cáo hóa học:" Human fallopian tube: a new source of multipotent adult mesenchymal stem cells discarded in surgical procedures" potx

... washed twice in phosphate saline buffer (PBS, Gibco, Invitrogen, Carlsbad, CA), finely minced with a scalpel, put inside a 15 or 50 mL falcon, and incubated in 5 ml of pure TripLE Express, (Invitrogen, ... possibility of using stem cells for regenerative medi- cine has opened a new field of investigation to find the best sources for obtaining multipotent stem cells, in par- ticula...

Ngày tải lên: 18/06/2014, 15:20

10 456 0
báo cáo hóa học:" KSP inhibitor ARRY-520 as a substitute for Paclitaxel in Type I ovarian cancer cells" potx

báo cáo hóa học:" KSP inhibitor ARRY-520 as a substitute for Paclitaxel in Type I ovarian cancer cells" potx

... activity of a kinesin inhibitor. Cancer Res 2004, 64:3276-3280. 26. Tao W, South VJ, Diehl RE, Davide JP, Sepp-Lorenzino L, Fraley ME, Arrington KL, Lobell RB: An inhibitor of the kinesin spindle ... and induce the secretion of pro-inflammatory cytokines and chemokines in Type I EOC cells [4,5]. Thus, our next objective was to determine the effect of ARRY-520 on NF-κB and cytokine p...

Ngày tải lên: 18/06/2014, 15:20

9 538 0
báo cáo hóa học:" Phase I/II open-label study of the biologic effects of the interleukin-2 immunocytokine EMD 273063 (hu14.18-IL2) in patients with metastatic malignant melanoma" docx

báo cáo hóa học:" Phase I/II open-label study of the biologic effects of the interleukin-2 immunocytokine EMD 273063 (hu14.18-IL2) in patients with metastatic malignant melanoma" docx

... approaches for introducing IL2 into the tumor environment include injection of the cytokine intratumorally [17] and administering intratu- moral injections of adenovirus encoding IL2 [18]. In the later ... post-dosing change in NK infiltration as detected by CD16 and CD56 IHC staining. This observa- tion is in contrast with findings in the peripheral blood that show no change in...

Ngày tải lên: 18/06/2014, 15:20

11 674 0
báo cáo hóa học:" A practical approach for the validation of sterility, endotoxin and potency testing of bone marrow mononucleated cells used in cardiac regeneration in compliance with good manufacturing practice" docx

báo cáo hóa học:" A practical approach for the validation of sterility, endotoxin and potency testing of bone marrow mononucleated cells used in cardiac regeneration in compliance with good manufacturing practice" docx

... are reported in Figure 3. Discussion Cellular therapy is an emerging field in medicine; all the stem cell medicinal products must be in compliance with principles and guidelines of good manufacturing ... substrate by an enzyme produced in the reaction of the lysate in the presence of endotoxin. The system con- sists of LAL reagents and endotoxin controls in the form of a...

Ngày tải lên: 18/06/2014, 15:20

9 775 0
Báo cáo hóa học: " S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis)" potx

Báo cáo hóa học: " S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis)" potx

... time of dosing to last observa- tion), and AUCinf Obs (area under the curve from time of dosing to infinity) were calculated using WinNonLin version 5.0 (Pharsight). Results Effect of S110 in Human ... doses of drug or co-administration of the cytidine deaminase inhibitor tetrahydouridine (THU; 8, 9). Even though S110 is resistant to cytidine deaminase, the rapid conversion of S...

Ngày tải lên: 18/06/2014, 16:20

8 443 0
w