... with a torque sensor measuring the total tor- que provided by both legs at the crank, but this signal does not allow to dist inguish the contribution provided by each leg during pedaling. To overcome ... gait, but still exhibited gait asymmetry due to an overuse of the healthy limb. In our experimental approach we tried to keep to the key ingredients for motor functional recovery pr...
Ngày tải lên: 19/06/2014, 08:20
... the tumor Elevated cytokines and growth factors in GBM-M2 cellsFigure 2 Elevated cytokines and growth factors in GBM-M2 cells. Identification of cytokines and growth factors in com- mon in the ... ability to acquire a proliferative pheno- type again to become a metastatic colony [40]. The changes in cytokine and growth factor expression that occur after ELM GBM-M2 selection are similar...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" A systematic approach to biomarker discovery; Preamble to "the iSBTc-FDA taskforce on immunotherapy biomarkers"" docx
... according to the variance expected in the study population and its responsiveness to therapy and/or susceptibility to toxic side effects (i.e. the expected frequency of responders to a given ... clinical strategies to increase the yield of informa- tion relevant to the mechanism of immune-mediated, tissue-specific rejection to develop clinically useful mark- ers and assays. To...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" A novel role of HLA class I in the pathology of medulloblastoma" docx
... Invasiveness in medul- loblastoma is mediated by several receptor activation pathways, such as platelet derived growth factor receptor and epidermal growth factor receptor [36]. Common components ... and invasion of medulloblastoma cells by concurrently inhibiting activation of platelet-derived growth factor receptor and transactivation of epidermal growth factor receptor. Mol Cancer Ther 200...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" A practical approach for the validation of sterility, endotoxin and potency testing of bone marrow mononucleated cells used in cardiac regeneration in compliance with good manufacturing practice" docx
... protocols, include several populations of stem cells able to restore vascularization or to transdif- ferentiate into functional cardiac cells: hematopoietic stem cells (HSC) which give rise to ... for endotoxin detection at the endo- toxin limit. To determine if any interfering characteristics exist, each LAL assay must have a positive product control (PPC) to ensure that endotoxin...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" A comparison of classification methods for predicting Chronic Fatigue Syndrome based on genetic data" potx
... 5-hydroxytryptamine receptor 2A (HTR2A), monoamine oxidase A (MAOA), monoamine oxidase B (MAOB), nuclear receptor sub- family 3; group C, member 1 glucocorticoid receptor (NR3C1), proopiomelanocortin (POMC) and tryptophan hydroxylase ... the glu- cocorticoid receptor in neural cells [37], and increases in glucocorticoid receptor expression in human skeletal muscle cells have been suggested t...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" A MIF haplotype is associated with the outcome of patients with severe sepsis: a case control study" pdf
... Mutation screening of the macrophage migration inhibitory factor gene: positive association of a functional polymorphism of macrophage migration inhibitory factor with juvenile idio- pathic arthritis. Arthritis ... Lopez-Nevot MA, Pinero A, de la Concha EG, Nieto A, Urcelay E, Martin J: Association of the macrophage migration inhibitory factor gene polymorphisms with inflammatory bowel diseas...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: " A quantitative real time PCR method to analyze T cell receptor Vb subgroup expansion by staphylococcal superantigens" doc
... al enterotoxins (SEs), SE-like (SEl) toxins and toxic shock syndrome toxin-1 (TSST-1), produced by Staphylococcus aureus, are prototypic microbial superantigens (SAgs). Members of this toxin subgroup * ... Bohach 1* Abstract Background: Staphylococcal enterotoxins (SEs), SE-like (SEl) toxins, and toxic shock syndrome toxin-1 (TSST-1), produced by Staphylococcus aureus, belong to the subgrou...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " A pilot clinical trial testing mutant von HippelLindau peptide as a novel immune therapy in metastatic Renal Cell Carcinoma" doc
... guanine to thymine that led to a substitution in serine to isoleucine at position 111. Patient 4 had a mutation at nucleotide number 343 resulting in a change from cytosine to guanine which led to ... response to the corresponding peptide had a significant elevation in T regulatory cells in the post vaccination samples. Safety and toxicity The vaccine was well tolera ted. No grade...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: "A randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ECOG 3899" pot
... to have prior treatment with bilateral orchiect- omy or other primary hormonal therapy with evidence of treatment failure (patients who had not undergone bilateral orchiectomy were required to ... disease related symp- toms with treatment associated symptoms. Thus, evalua- tion of patients’ symptoms and QOL was an important endpoint in the study [15]. Methods Patients To be eligible...
Ngày tải lên: 18/06/2014, 16:20