báo cáo hóa học: " Interleukin-1alpha expression precedes IL-1beta after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues" pdf

... regulation of its release and sterile inflammatory responses [11]. Interleukin-1α expression precedes IL-1β after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral ... primary injury to brain cells is caused by the lack of blood supply and so can be considered sterile. Sterile inflammation is known as a...

Ngày tải lên: 19/06/2014, 22:20

... anti-inflammatory mediators are enhanced [13]. The role of TLR4 in ischemic brain tolerance Pre-exposur e of the brain to a shor t ischemic even t can result in subsequent resistan ce to severe ischemic injury [13], ... of 11 The role of TLR9 in ischemic brain tolerance Recently TLR9 was shown to induce tolerance to brain ischemia [50]. Systemic administratio...

Ngày tải lên: 19/06/2014, 22:20

... group of diseases in terms of their biology and the clinical course. The diag- nosis and classification of lung cancers are primarily based on the histological morphology and immunohisto- logical ... fibrotic focus is regarded as an indicator of tumor angiogenesis and independent predictor of early metastasis [35]. SCLCs show an up-regulation of 3 proto-oncogenes, which...

Ngày tải lên: 18/06/2014, 15:20

... setting to support the histological diagnosis of prostate cancer. Because it has characteristics of cancer-specific expression and fre- quent expression in various cancers, AMACR is an attrac- tive ... target of inhibitor of apoptosis protein family, Livin/ML-IAP in lung cancer. Clin Cancer Res 2005, 11:1000-1009. 16. Sato T, Sato N, Takahashi S, Koshiba H, Kikuchi K: Specif...

Ngày tải lên: 18/06/2014, 15:20

... of the histone acetyltransferase family of transcriptional coactivator, is found to play a variety of roles in the transcription process and catalyzes histone acetylation through its histone acetyltransferase ... correlates with nuclear alterations of tumor cells and contributes to the growth of prostate carcinoma and is a predictor of aggressive features of this c...

Ngày tải lên: 18/06/2014, 16:20

... a decrease in the expression of chemokines and adhesion molecules. Another possibility is the exhaustion of infil- trating leukocytes due to apoptosis. Many studies have demonstrated apoptosis of infiltrating ... induction of EAE and preparation of tissues (SE, DS, MN), in situ hybridization and immunohisto- chemistry (DS, SE, MN, AE-D), analysis of data (DS, SE, HL, A...

Ngày tải lên: 19/06/2014, 22:20

... (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs), and an increases of the expression of proinflam- matory cytokines IL-1β and TNF-α [14-16]. Thus, differen- tial gene expression ... implications for our understanding of mechanosensitivity of cartilage and mechanical regulation of chondrocyte gene expression. Published: 06 December 2006 Journal of O...

Ngày tải lên: 20/06/2014, 00:20

... resulted the KCs to change expression patterns of the other KC differentia- tion markers by reducing expression of basal keratins K14 and increasing expression of keratins K1 and K10 (data not ... KCs Effects of post-transfection treatment of methylcellulose on expression of PV L1 genes in mouse primary KCsFigure 2 Effects of post-transfection treatment of methyl...

Ngày tải lên: 20/06/2014, 01:20

... provides a potential tool to further dissect the molecular mecha- nisms of aphid transmission. Expression of hairpin RNAs driven by tissue-specific regulatory sequences could be employed to abort virus ... between the sense and the antisense orienta- tions of the PVY CP sequence. We took advantage of the positive selection conferred by this prokaryotic resistance gene to red...

Ngày tải lên: 20/06/2014, 01:20