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báo cáo hóa học: " Apolipoprotein E expression is elevated by interleukin 1 and other interleukin 1-induced factors" ppt

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báo cáo hóa học: " Apolipoprotein E expression is elevated by interleukin 1 and other interleukin 1-induced factors" ppt

... cytokines is elevated, the expression of IL -1- driven AD-related proteins such as ApoE would be elevated as well. Multiple MLKs—ERK, p38-MAPK, and JNK—were shown to be involved in elevated expression ... made available soon. Apolipoprotein E expression is elevated by interleukin 1 and other interleukin 1- induced factorsJournal of Neuroinflammation 2 011 , 8 :17 5 doi :10 .11 86 /17 42-2094-8 -17 5Ling Liu ... **p<0. 01. Apolipoprotein E expression is elevated by interleukin 1 and other interleukin 1- induced factors Ling Liu 1 ; Orwa Aboud 1 ; Richard A Jones 1 ; Robert E Mrak4; W Sue T Griffin 1- 3*;...
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Báo cáo hóa học: " Alterations in intracellular potassium concentration by HIV-1 and SIV Nef" pptx

... linked to each dyerenders the molecule uncharged and thereby able to per-meate living cell membranes. Once inside the cell, thelipophilic blocking groups are cleaved by endogenous cel-lular esterases, ... that exogenous Nef causes cell deathin yeast and bacterial cell due to permeabilization of thecell membranes [32].This effect of Nef proteins shown in this study requires thepresence of the ... supplemented with 10 % fetalbovine serum[6] (GIBCO, Long Island, NY), penicillin (10 0 U/ml) and streptomycin (10 0 µg/ml). Oocytes wereremoved from anesthetized Xenopus laevis, and preparedfor electrophysiological...
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báo cáo hóa học: " Apolipoprotein E-specific innate immune response in astrocytes from targeted replacement mice" pptx

... this rea-son, other apoE-isoform specific mechanisms likely existto explain the apparent influence of APOE alleles on sucha broad spectrum of neurologic diseases; indeed, severalhave been ... HIV-infected subjects with the E4 allele forAPOE have excess dementia and peripheral neuropathy. NatMed 19 98, 4 :11 82 -11 184.7. Nathoo N, Chetty R, van Dellen JR, Barnett GH: Genetic vulnera-bility ... modulate the risk of developing AD [12 ], the influence of inheriting different APOE allelesextends well beyond diseases thought to involve Aβ pep-tide-mediated neurotoxicity, as noted above. For...
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báo cáo hóa học: " Apolipoprotein E isoform-dependent dendritic recovery of hippocampal neurons following activation of innate immunity" pot

... demonstratedthat despite brain regional differences in apoE expression, there are no isoform-specific differences in levels of apoEin brain tissue from these TR APOE mice, even with ele-vated apoE2 ... μg of eachsample separated by gel electrophoresis, transferred and western blotted as previously described by us [43]. Signalwas developed by enhanced chemiluminescence (Amer-sham, Piscataway, ... dendritic degeneration in the absence of febrileresponse, discernable tissue damage, adaptive immunecell infiltrate, or detectable neuron loss [3]. We investi-gated changes in both proximal and distal...
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báo cáo hóa học:" Bcl-2 expression is altered with ovarian tumor progression: an immunohistochemical evaluation" pptx

... between tumor types and staining intensity ofepithelial and stromal staining between tissue types. TheCochran-Mantel-Haenszel test was used to test for inde-pendence between tissue type and ... lymphocyte nest size.The generalized linear model, along with pair-wise com-parison among tissue types was used to test for differencesin tissue type and the number of lymphocyte nestspresent.ResultsImmunohistochemical ... will be:available free of charge to the entire biomedical communitypeer reviewed and published immediately upon acceptancecited in PubMed and archived on PubMed Central yours — you keep the copyrightSubmit...
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báo cáo hóa học:" Nuclear survivin expression is a positive prognostic factor in taxane-platinum-treated ovarian cancer patients" pdf

... treated with eitherchemotherapeutic regimen has been presented inTable 2.There were no associations between the cytoplasmic and nuclear survivin expression, nor between survivinFigure 1 Various ... June 2 011 Accepted: 10 November 2 011 Published: 10 November 2 011 References 1. Ambrosini G, Adida C, Altieri DC: A novel anti-apoptosis gene, survivin,expressed in cancer and lymphoma. Nat Med ... backwardselection technique, where factors not significa nt at 0 .1 were removed stepwise from the model.The analyses were performed in the two groups ofpatients treated with different chemotherapeutic regi-mens,...
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báo cáo hóa học: " Peripheral reductive capacity is associated with cognitive performance and survival in Alzheimer''''s disease" potx

... artery disease and different atherogenic risk factors. J Intern Med 2004,256:308- 315 . 13 . Wenham PR, Price WH, Blandell G: Apolipoprotein E genotyping by one-stage PCR. Lancet 19 91, 337 :11 58 -11 59. 14 . ... cognitive scores and AOC levels of the participants. Asexpected, we found significant differences between con-trols and patients with respect to MMSE, LSS and the pres-ence of the APOE ε4 allele. ... scores (A) or on cognitive decline (B), defined as the difference between MMSE scores over a period of 2.0 (0.2) [median(IQR/2)] yearsFigure 3Dependence of serum AOC levels on MMSE scores (A)...
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báo cáo hóa học:" High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area" pdf

... the integrity of the genome [15 ,16 ]. The enzyme excision repair cross-complementa-tiongroup1(ERCC1)playsaratelimitingroleinthenucleotide excision repair pathway, and its expression has been ... withadvanced-stage gastric, ovarian, c olorectal, esophageal, and non-small-cell lung cancers [15 ,17 ,19 - 21] . However,there are only few studies to elucidate the relationshipbetween ERCC1 expression and ... found to be involvedin betel nut-related HNSCC [26,27]. However, the rela-tionship between betel nut and ERCC1 expressio n hasnot been reported before. In this study, we find tissuesamples from...
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báo cáo hóa học:" Liver mitochondrial dysfunction is reverted by insulin-like growth factor II (IGF-II) in aging rats" pot

... authors declare that they have no competing interests. These resultshave been registered as P2006 015 23.Received: 26 February 2 011 Accepted: 28 July 2 011 Published: 28 July 2 011 References 1. Hoffman ... 9 :12 3http://www.translational-medicine.com/content/9 /1/ 123© 2 011 Garcia-Fernandez et al; licensee BioMed Central Ltd. This is an Open Access article distributed un der the terms of the CreativeCommons Attribution License ... Understanding that aging is an unrecognized condi-tion of “IGF-I deficiency”, we have recently reportedthat IGF-I replacement therapy restores many age-related changes increasing testosterone...
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Báo cáo hóa học: " Quality of Life as reported by school children and their parents: a cross-sectional survey" docx

... QoL related to their asthmatic children,there were no major gender differences between mother and father ratings of QoL. However, mothers were moredisturbed at night, and felt more helpless and ... Ninety-eight students had to be excludedbecause they either lacked sufficient competence in theNorwegian language (refugees, n = 51) , and/ or becausethey had an academic developmental level ... between two groupmeans were analysed by independent t-test for continu-ous variables.Differences in disagreement between informants on theILC were analysed by the McNemar test. Effect sizes...
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