báo cáo hóa học: " Conformational epitopes of myelin oligode

báo cáo hóa học: " Conformational epitopes of myelin oligodendrocyte glycoprotein are targets of potentially pathogenic antibody responses in multiple sclerosis" pot

... 8:161 http://www.jneuroinflammation.com/content/8/1/161 Page 7 of 9 RESEARCH Open Access Conformational epitopes of myelin oligodendrocyte glycoprotein are targets of potentially pathogenic antibody responses in multiple sclerosis Til ... C, Schubart AS, Linington C: Commentary: Sorting the wheat from the chaff: identifying demyelinating components of the my...

Ngày tải lên : 19/06/2014, 22:20

9 319 0

Báo cáo hóa học: " Herpes Simplex Virus Type 1 Us3 Gene Deletion Influences Toll-like Receptor Responses in Cultured Monocytic Cells" pdf

... TLR9-dependent and -independent pathways are involved in IFN-α production in HSV infection [17]. In interferon-producing cells (IPCs) the MyD88-dependent pathway in TLR9 sign- aling mediates the secretion of ... protein inducing IFN-β (TRIF) leading to IRF-3 or NF-κB activation [2]. The interaction of TRIF and non- canonical IκB kinases IKKε and TANK-binding kinase 1 (TBK1) le...

Ngày tải lên : 20/06/2014, 01:20

11 361 0

báo cáo hóa học:" Neopterin production and tryptophan degradation during 24-months therapy with interferon beta-1a in multiple sclerosis patients" pot

... Nevertheless, since no relations have been found between neopterin and clinical progression, there are issues regarding the use of neopterin as a measure of the clinical efficacy of IFNb. It is ... Silvia Marino 3 , Valentina Zipoli 4 , Marino Zorzon 8 and Enrico Millefiorini 11 Background: Increased synthesis of neopterin and degradation of tryptophan to kynurenine, measured as k...

Ngày tải lên : 20/06/2014, 03:20

9 330 0

báo cáo hóa học:" Gene expression profiling for molecular distinction and characterization of laser captured primary lung cancers" ppt

... removed from the training set. The other samples are reduced to those 50 genes with the highest signal-to-noise ratio, which are used as a training set in a training series. A training series generates ... spreading. The extracellular cell matrix receptors integrin alpha-3 and integrin beta-2 as well as the collagen binding protein-1 (SERPHINH1) were upregulated in AC. These genes hav...

Ngày tải lên : 18/06/2014, 15:20

17 662 0

báo cáo hóa học:" Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance" docx

... with a poor clinical outcome in CLL [2-8]. In the present review, the main factors playing a role in defining the biological features of CLL cells, hence eventu- ally influencing the clinical aggressiveness ... permits the develop- ment of a more specific antigen-binding site by maintain- ing the necessary supporting scaffold of BCR [6,72-76]. From a clinical point of view, in...

Ngày tải lên : 18/06/2014, 15:20

14 640 0

báo cáo hóa học:" A MIF haplotype is associated with the outcome of patients with severe sepsis: a case control study" pdf

... local wound infection rates reflected overall infection rates of this group of patients. The baseline char- acteristics of the both patient groups are outlined in Table 1. The mean age of healthy ... patients at risk of dying. List of Abbreviations AP-1: Activator protein-1; CI: Confidence interval; ICU: Intensive care unit; IL-6: Interleukin-6; MIF: Macrophage migration inhib...

Ngày tải lên : 18/06/2014, 15:20

8 554 0

Báo cáo hóa học: " Robust TLR4-induced gene expression patterns are not an accurate indicator of human immunity" ppt

... IRAK4-kinase-dead knock -in mic e also fail, in vitro and in vivo,toproduce inflammatory cytokines in response to LPS and are pro- tected against LPS-induced sepsis in vivo [1 9,22-24]. There is, however, a resounding ... demonstrated that innate defence regulator peptides, which s uppress pro-inflammatory cytokines but substantially maintain chemokine responses, are able to pro...

Ngày tải lên : 18/06/2014, 16:20

12 698 0

báo cáo hóa học: " Primary Sjögren''''s Syndrome: health experiences and predictors of health quality among patients in the United States" potx

... nature of the presenting symptoms or to poor physician awareness of PSS in general and confirms that, despite a growing quantity of research regarding the sever- ity of sicca symptoms and range of ... sicca. The domain scores, including somatic and mental fatigue domains, may be used independently or combined into a composite fatigue score (ProF), or further summarized to indices...

Ngày tải lên : 18/06/2014, 18:20

9 566 0

báo cáo hóa học: " Associations between Cardiorespiratory Fitness and Health-Related Quality of Life" pdf

... health-related quality of life. HRQOL is defined as the perception of overall satisfaction with life and involves the measurement of functional sta- tus in the domains of physical, cognitive, ... important in defining health benefits? Med Sci Sports Exerc 2001, 33:379-99. 7. Ware JE, Kosinski M, Keller SD: A 12-Item Short-Form Health Survey: construction of scales and preliminar...

Ngày tải lên : 18/06/2014, 18:20

5 398 0

báo cáo hóa học: " Relationship between the EQ-5D index and measures of clinical outcomes in selected studies of cardiovascular interventions" pot

... developed, they are often tested in clinical tri- als against current treatment options. Clinical trial-based evaluations of treatments in many fields, including cardiology, often include cost-effective- ness, ... considered clinically significant [26]. In this study we assessed the change in EQ-5D index for a ten year increase in age, males versus females, a one minute increase...

Ngày tải lên : 18/06/2014, 19:20

14 610 0