báo cáo hóa học: " Reduced inflammation accompanies diminished myelin damage and repair in the NG2 null mouse spinal cord" potx

... important in under- standing changes in demyelination and remyelination in the NG2 null mouse. Although it remains to be determined whether changes in cytokine expression in the NG2 null mouse are ... in wild type mice, with both myelin damage and repair being reduced in the NG2 null mouse. These studies identify NG2 as an important factor in...

Ngày tải lên: 19/06/2014, 22:20

... [31-33]. Furthermore, hepatic lipase and Star expression can be modulated by insulin [34,35] and lep- tin [34,36]. The hyperinsulinemia/insulin-resistance of the obese LY mice may contribute to the elevated ... hyperinsulinemia/insulin resist- ance [37]. Moreover, leptin bi-phasically modulates granulosa cell Star expression [36]. An interesting and unexpected finding was the re...

Ngày tải lên: 20/06/2014, 07:20

... fact checked the changes. SM fully reviewed and edited the next draft. JVL and MW addressed the reviewer’s comments. All authors read and approved the final manuscript. Competing interests The authors ... HIV- related travel restrictions. In these cases, we contacted focal points and NGOs, receiving replies from every country except Israel. The resulting information and...

Ngày tải lên: 20/06/2014, 08:20

... dysfunction and inflammation appear to alter BBB integrity [43,44]. Recent evidence indicates that the integrity of the BBB, especially leukocyte endothelial adhesion may also be involved in the ... mtDNA, TNF and VEGF), some of which increase the expression of vascular endothelial cell adhesion molecules (VCAMs) and permit exit of circulating lymphocytes in the bra...

Ngày tải lên: 19/06/2014, 22:20

... mechanism, in this regard, is the presence of scaffolding domain in caveolin- 1 that binds to and inhibits the activity of several signaling proteins in vitro and in situ, including the EGF and Neu receptors, ... purposes) advises on the work and helped with the interpretation of the data, WYF, AW, EW and DFS supervised all the work and wrote the paper toge...

Ngày tải lên: 18/06/2014, 15:20

... allow us to infer causality. Cautions should be exer- cised when interpreting and generalizing the current findings in other populations as the present sample con- sisted of mainly Chinese female ... manuscript; RF participated in editing the manuscript. All authors read and approved the final manuscript. Competing interests The authors declare that they have no competing in...

Ngày tải lên: 18/06/2014, 19:20

... training and testing the classifier using only the feature with the highest MI score, and then calculated the fitness. Then we added features one at a time (according to their MI scores) and ... subject, IC and NC epochs were randomized and divided into train- ing, validation and test sets. The training set was used to train the classifier, and the validation set w...

Ngày tải lên: 19/06/2014, 10:20

... IL-18 production in murine brains within 24 hours. In contrast, the intracerebral injection of murine Intracerebral IL-18 concentrations in mice, as determined by ELISA in murine brain homogenates ... expression and posttraumatic regulation in the injured brain [3,12,13]. However, the TNF-dependent regulation of IL- 18 in the injured brain has not yet been investigated....

Ngày tải lên: 19/06/2014, 22:20

... of monocytes and macrophages across the BBB to the sites of axonal injury in the brain [33,37]. Both in vitro and in vivo findings suggest that hypoxia/ischemia-induced infiltra- tion of monocytes and ... important role in the initiation and propagation of hypoxia/ischemia-induced inflammation by secreting inflammatory chemokines that attract neutrophils and monocy...

Ngày tải lên: 19/06/2014, 22:20

... responsible. The most recent of these occurred in June of 2005 in the state of Indiana. Other outbreaks in the Americas include Mexico in 1988 and more recently, in 2004, Uruguay and Cuba. As with other ... be replacing the original RHDV serotype in Europe [37] and an original RHDV strain from China in 1984 (WX84 China, Figures 2 and 4) does not carry the RHDVa...

Ngày tải lên: 20/06/2014, 01:20