báo cáo hóa học: " HIV-1 and IL-1b regulate astrocytic CD38 through mitogen-activated protein kinases and nuclear factor-B signaling mechanisms" ppt

báo cáo hóa học: " HIV-1 and IL-1b regulate astrocytic CD38 through mitogen-activated protein kinases and nuclear factor-B signaling mechanisms" ppt

báo cáo hóa học: " HIV-1 and IL-1b regulate astrocytic CD38 through mitogen-activated protein kinases and nuclear factor-B signaling mechanisms" ppt

... and beyond. J Neurovirol 2004, 10(Suppl 1):97-101. doi:10.1186/1742-2094-8-145 Cite this article as: Mamik et al.: HIV-1 and IL-1b regulate astrocytic CD38 through mitogen-activated protein kinases ... proinflammatory cytokine IL-1b upregulates Fas ligand in astrocytes, which induces apoptosis in neurons [45,53], and that IL-1b- mediated production of CCL2 and CX...
Ngày tải lên : 19/06/2014, 22:20
  • 13
  • 251
  • 0
Báo cáo hóa học: " Research Article A Study of Residue Correlation within Protein Sequences and Its Application to Sequence Classification" pptx

Báo cáo hóa học: " Research Article A Study of Residue Correlation within Protein Sequences and Its Application to Sequence Classification" pptx

... (hydrophilic/hydrophobic) interac- tions. Protein sequences contain sufficient information to construct secondary and tertiary protein struc tures. Most methods for predicting protein structure rely on primary ... correlation of amino acids within and across protein sequences [1–3]. Despite all this, in terms of character strings, proteins can be regarded as slightly edited random s...
Ngày tải lên : 22/06/2014, 19:20
  • 9
  • 374
  • 0
báo cáo hóa học:" Highly efficient transduction of human plasmacytoid dendritic cells without phenotypic and functional maturation" docx

báo cáo hóa học:" Highly efficient transduction of human plasmacytoid dendritic cells without phenotypic and functional maturation" docx

... (CD123) and the CD4 [18]. Moreover, as a hallmark of pDC, these cells are BDCA2 and BDCA4 (type II C lectin)-positive and CD11c- and CD1a-negative. Trypan blue exclusion and cell counting of LV and ... (pRRL-SIN -PPT- hPGK-GFP-WPRE, pRRL- SIN -PPT- hEF1-GFP-WPRE, pRRL-SIN -PPT- C512-GFP- WPRE, or pRRL-SIN -PPT- desmin-GFP-WPRE or pRRL- SIN -PPT- C512-MART1-WPRE the packaging const...
Ngày tải lên : 18/06/2014, 15:20
  • 12
  • 374
  • 0
báo cáo hóa học:" Regression of orthotopic neuroblastoma in mice by targeting the endothelial and tumor cell compartments" pdf

báo cáo hóa học:" Regression of orthotopic neuroblastoma in mice by targeting the endothelial and tumor cell compartments" pdf

... the left adrenal gland in SCID mice through a flank incision. Nine weeks later, a new laparotomy was performed to confirm tumor establishment and to estimate tumor volume. Animals were randomized to ... treatment outcome. CgA is an acidic, monomeric protein and is co-stored and co-released with catecholamines from secretory granules in neural, endocrine, and neuroendocrine cells [...
Ngày tải lên : 18/06/2014, 15:20
  • 11
  • 593
  • 0
báo cáo hóa học:" Short term effects of milrinone on biomarkers of necrosis, apoptosis, and inflammation in patients with severe heart failure" pot

báo cáo hóa học:" Short term effects of milrinone on biomarkers of necrosis, apoptosis, and inflammation in patients with severe heart failure" pot

... soluble Fas, and soluble Fas-ligand (all p < 0.05) indicative of reduced inflammatory and apoptotic signaling compared to baseline. Conclusion: In conclusion, among patients with severe HF and low ... manufacturer protocol and using standard curves and software. The kits for NTproBNP (fmol/ml) were purchased from ALPCO Diagnostics, Salem, New Hampshire; for IL-6 (pg/ml) and T...
Ngày tải lên : 18/06/2014, 15:20
  • 6
  • 465
  • 0
Báo cáo hóa học: " Adipose-derived mesenchymal stem cells markedly attenuate brain infarct size and improve neurological function in rats" pptx

Báo cáo hóa học: " Adipose-derived mesenchymal stem cells markedly attenuate brain infarct size and improve neurological function in rats" pptx

... CM-Dil and DAPI, and CM-Dil and vWF (Figure 11) To determine whether transplanted ADMSCs were really homing to the BIA, double stain of CM-Dil and DAPI was done. As expected, the CM-Dil and DAPI-pos- itively ... have read and approved the final manuscript. CMY and SL designed the experiment, drafted and performed animal experiments. YCL, CHY, and YHK were responsible for th...
Ngày tải lên : 18/06/2014, 16:20
  • 16
  • 488
  • 0
Báo cáo hóa học: " First-line chemoimmunotherapy in metastatic breast carcinoma: combination of paclitaxel and IMP321 (LAG-3Ig) enhances immune responses and antitumor activity" pptx

Báo cáo hóa học: " First-line chemoimmunotherapy in metastatic breast carcinoma: combination of paclitaxel and IMP321 (LAG-3Ig) enhances immune responses and antitumor activity" pptx

... guidelines, and all applicable local laws and regulations. The study protocol and amendments were approved by an institutional review board and an independent ethics committee. Study design and treatments In ... performed the statistical analysis. MG and FT conceived the study, and participated in its design and coordination and helped draft the manuscript. All authors read...
Ngày tải lên : 18/06/2014, 16:20
  • 11
  • 472
  • 0
Báo cáo hóa học: " Three-day dendritic cells for vaccine development: Antigen uptake, processing and presentation" pot

Báo cáo hóa học: " Three-day dendritic cells for vaccine development: Antigen uptake, processing and presentation" pot

... to Figure 1 Morphology and FITC-dextran uptake of 3d mDC and 7d mDC. The size and the morphology of immature and mature 3d DC and 7d DC were analyzed by (A) flow cytometry and (B) light microscopy. ... contributions MB designed and performed the experiments and drafted the manuscript. SS and SW contributed to the initial developme nt of 3d DC and provided scientific and...
Ngày tải lên : 18/06/2014, 16:20
  • 13
  • 412
  • 0
Báo cáo hóa học: "Retention of progenitor cell phenotype in otospheres from guinea pig and mouse cochlea" ppt

Báo cáo hóa học: "Retention of progenitor cell phenotype in otospheres from guinea pig and mouse cochlea" ppt

... postnatal mouse cochlea and vestibular sys- tem[12,13], and adult human and guinea pig spiral ganglion[27]; (2) spheres were shown to be clonal and capable of self renewal[12,13]; and (3) spheres were ... supporting cells[32-37]. Nestin is an intermediate filament protein expressed by stem and progenitor cells early in development, and throughout the ea rly postnatal period in...
Ngày tải lên : 18/06/2014, 16:20
  • 10
  • 476
  • 1
Báo cáo hóa học: " High expression of transcriptional coactivator p300 correlates with aggressive features and poor prognosis of hepatocellular carcinoma" doc

Báo cáo hóa học: " High expression of transcriptional coactivator p300 correlates with aggressive features and poor prognosis of hepatocellular carcinoma" doc

... 11 tissues (Figure 2A). Up-regulated expression of p300 protein was observed in 6/8 (75.0%) HCCs, and in each of the four cases with up-regulated p300 protein, up- regulated p300 mRNA was observed ... malignant feature and/ or worse prognosis of this tumor. Previous study also suggested that putative p300 and CREB complex might up -regulate the H3 and H4 acetyl ation levels, and...
Ngày tải lên : 18/06/2014, 16:20
  • 11
  • 425
  • 0